眠安宁颗粒联合右佐匹克隆治疗失眠症的疗效及对患者甲状腺激素T3、T4、TSH水平的影响
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摘要
目的探讨眠安宁颗粒联合右佐匹克隆治疗失眠症的效果及对患者甲状腺激素水平的影响。方法选取2015年12月至2017年12月因失眠症于本院就诊的84例患者纳入研究并采用随机数字表法分组。对照组42例用右佐匹克隆治疗,观察组42例联合眠安宁颗粒,4周后比较临床疗效。结果治疗后观察组睡眠质量指数(PSQI)低于对照组,差异有统计学意义(P<0.05);治疗后观察组T3、T4、TSH低于对照组(P<0.05);观察组总有效率95.24%(40/42),高于对照组的76.19%(32/42),差异具统计学意义(P<0.05)。结论眠安宁颗粒联合右佐匹克隆治疗失眠症效果显著,可有效降低T3、T4、TSH水平,值得推广。
Objective To investigate the effect of miananning capsule combined with eszopiclone on insomnia and its effect on thyroid hormone levels. Methods 84 patients who were admitted to our hospital from insomnia from December 2015 to December 2017 were enrolled in the study and randomized using a random number table. 42 patients in the control group were treated with dextrozopicl, and 42 patients in the observation group were treated with Hemiananning granules. The clinical efficacy was compared after 4 weeks. Results After treatment, the sleep quality index(PSQI) of the observation group was lower than that of the control group(P<0.05). After treatment, the T3, T4 and TSH of the observation group were lower than the control group(P<0.05). The efficiency was 95.24%(40/42), which was higher than that of the control group 76.19%(32/42),the difference was statistically significant(P<0.05). Conclusion Miananning capsule combined with eszopiclone is effective in the treatment of insomnia, which can effectively reduce the levels of T3, T4 and TSH. It is worthy of promotion.
Objective To investigate the effect of miananning capsule combined with eszopiclone on insomnia and its effect on thyroid hormone levels. Methods 84 patients who were admitted to our hospital from insomnia from December 2015 to December 2017 were enrolled in the study and randomized using a random number table. 42 patients in the control group were treated with dextrozopicl, and 42 patients in the observation group were treated with Hemiananning granules. The clinical efficacy was compared after 4 weeks. Results After treatment, the sleep quality index(PSQI) of the observation group was lower than that of the control group(P<0.05). After treatment, the T3, T4 and TSH of the observation group were lower than the control group(P<0.05). The efficiency was 95.24%(40/42), which was higher than that of the control group 76.19%(32/42),the difference was statistically significant(P<0.05). Conclusion Miananning capsule combined with eszopiclone is effective in the treatment of insomnia, which can effectively reduce the levels of T3, T4 and TSH. It is worthy of promotion.
引文
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[2]梁英,汪卫东,张鸿燕,等.舒眠胶囊与解郁安神胶囊治疗失眠症(肝郁伤神证)多中心随机双盲对照研究[J].中国新药杂志,2015,24(10):1155-1159.
[3]武田昌幸,李石良.失眠症[M].北京:中国中医药出版社,2002:127-131.
[4]张洁,鲁剑萍.中药足浴联合耳穴压豆对失眠患者的疗效观察[J].上海护理,2017,17(3):34-36.
[5]尹君,张韬,盖红梅,等.老年人失眠症原因及干预的研究进展[J].中国实用护理杂志,2014,30(1):178-179.
[6]Sivertsen B,Lallukka T,Salo P,et al.Insomnia as a risk factor for ill health:results from the large population-based prospective HUNT Study in Norway[J].J Sleep Res,2014,23(2):124-132.
[7]卢献彬,高吉昌,曹瑞芬,等.右佐匹克隆联合黛力新治疗AMI焦虑、抑郁伴失眠患者的临床分析[J].现代中西医结合杂志,2014,23(24):2682-2684.
[8]王玉玲,张红亮,郭志平,等.右佐匹克隆治疗老年原发性失眠症的疗效及安全性分析[J].中国临床保健杂志,2015,18(2):200-201.
[9]夏路风,李六水,张琪,等.舒眠胶囊与艾司唑仑治疗失眠症的临床疗效比较[J].安徽医药,2015,19(2):367-371.
[10]刘娅萍,柴春艳,王甜,等.舒眠胶囊联合右佐匹克隆治疗失眠症的临床研究[J].现代药物与临床,2017,32(17):2108-2111.