摘要
<正>慢性心力衰竭(慢性心衰)是心血管疾病的终末表现和最主要的死因,也是21世纪心血管领域的两大挑战之一。肾素-血管紧张素-醛固酮系统(reninangiotensin-aldosterone system,RAAS)和交感神经系统(sympathetic nervous system,SNS)在慢性心衰的发展中发挥重要作用。目前,RAAS阻断
引文
[1]Sobotka P,Mahfoud F,Schlaich M P,et al.Sympatho-renal axis in chronic disease[J].Clin Res Cardiol,2011,100(12):1049-1057.
[2]Paul K,Whelton M,Robert M,et al.Renal sympathetic denervation for treatment of patients with heart failure:summary of the available evidence[J].Am J Physiol Heart Circ Physiol,2017,11(1):12.
[3]Bohm M,Ewen S,Mahfoud F,et al.Renal denervation for chronic heart failure:background and pathophysiological rationale[J].Korean Circ J,2017,47(1):9-15.
[4]Bohm M,Linz D,Ukena C,et al.Renal denervation for the treatment of cardiovascular high risk-hypertension or beyond[J]?Circ Res,2014,115(3):400-409.
[5]Hong Z,Xuefei L,Neeru M,et al.Renal denervation improves cardiac function in rats with chronic heart failure:Effects on expression of adrenoceptors[J].Am J Physiol Heart Circ Physiol,2016,31(1):337-346.
[6]Patel K,Xu B,Liu X,et al.Renal denervation improves exaggerated sympathoexcitation in rats with Heart failure:a role for neuronal nitric oxide synthase in the paraventricular nucleus[J].Hypertension,2016,68(1):175-184.
[7]Hu W,Zhao Q Y,Yu S B,et al.Renal sympathetic denervation inhibits the development of left ventricular mechanical dyssynchrony during the progression of heart failure in dogs[J].Cardiovasc Ultrasound,2014,12:47.
[8]Zhao Q,Huang H,Wang X,et al.Changes of serum neurohormone after renal sympathetic denervation in dogs with pacinginduced heart failure[J].Int J Clin Exp Med,2014,7(11):4024-4030.
[9]Wang N,Zheng X,Qian J,et al.Renal sympathetic denervation alleviates myocardial fibrosis following isoproterenol-induced heart failure[J].Mol Med Rep,2017,16(4):5091-5098.
[10]Brandt M C,Mahfoud F,Reda S,et al.Renal sympathetic denervation reduces left ventricular hypertrophy and improves cardiac function in patients with resistant hypertension[J].J Am Coll Cardiol,2012,59(10):901-909.
[11]Chen P,Leng S,Luo Y,et al.Efficacy and safety of renal sympathetic denervation on dogs with pressure overload-induced Heart failure[J].Heart Lung Circ,2017,26(2):194-200.
[12]Hu J,Li Y,Cheng W,et al.A comparison of the efficacy of surgical renal denervation and pharmacologic therapies in post-myocardial infarction heart failure[J].PLoS One,2014,9(5):12-15.
[13]Yancy C W,Jessup M,Bozhurl B,et al.2013ACCF/AHAguideline for the management of heart failure:a report of the american college of cardiology foundation/American Heart Association Task Force on Practice Guidelines[J].J Am Coll Cardiol,2013,62(16):147-239.
[14]Davies J,Manisty C,Petraco R,et al.First-in-man safety evaluation of renal denervation for chronic systolic heart failure:primary outcome from REACH-Pilot study[J].Int JCardiol,2013,162(3):189-192.
[15]Fukuta H,Goto T,Wakami K,et al.Effects of catheterbased renal denervation on heart failure with reduced ejection fraction:a systematic review and meta-analysis[J].Heart Fail Rev,2017,11(9):12.
[16]Almeida M,Goncalves P,Branco P,et al.Impact of renal sympathetic denervation on left ventricular structure and Function at 1-year follow-up[J].PLoS One,2016,11(3):14-15.
[17]Hopper I,Gronda E,Hoppe U C,et al.Sympathetic response and outcomes following renal denervation in patients with chronic heart failure:12-month outcomes from the symplicity HF feasibility study[J].J Card Fail,2017,23(9):702-707.
[18]Qiming D,Benwen W,Genshan M.Effect of percutaneous renal sympathetic nerve radiofrequency ablation in patients with severe heart failure[J].Heart Fail Rev,2015,11(9):12.
[19]Schirmer S,Sayed M,Reil J C,et al.Improvements in left ventricular hypertrophy and diastolic function following renal denervation:effects beyond blood pressure and heart rate reduction[J].J Am Coll Cardiol,2014,63(18):1916-1923.
[20]Bohm M,Ewen S,Kindermann I,et al.Renal denervation and heart failure[J].Eur J Heart Fail,2014,16(6):608-613.
[21]Mahfoud F,Urban D,Teller D,et al.Effect of renal denervation on left ventricular mass and function in patients with resistant hypertension:data from a multi-centre cardiovascular magnetic resonance imaging trial[J].Eur Heart J,2014,35(33):2224-2231.
[22]Ott C,Mahfoud F,Schmid A,et al.Improvement of albuminuria after renal denervation[J].Int J Cardiol,2014,173(2):311-315.
[23]Witkowski A,Prejbisz A,Florczak E,et al.Effects of renal sympathetic denervation on blood pressure,sleep apnea course,and glycemic control in patients with resistant hypertension and sleep apnea[J].Hypertension,2011,58(4):559-565.
[24]Jason T,Bryan R,Kristine R,et al.Do Bayesian adaptive trials offer advantages for comparative effectiveness research?Protocol for the RE-ADAPT study[J].Clinical Trials,2013,10:807-827.
[25]Bhatt D L,Kandzari D E,Neill W W,et al.A controlled trial of renal denervation for resistant hypertension[J].The NEngl J Med,2014,370:1393-1401.