多学科诊治金黄色葡萄球菌脓毒症
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摘要
<正>越来越多的研究证实,金黄色葡萄球菌外毒素和细胞壁成分均可通过刺激机体炎症介质的大量合成与释放诱发脓毒症[1]。本文介绍多学科综合治疗模式诊治1例金黄色葡萄球菌脓毒症的过程,以期为此类疾病的诊治提供模式借鉴。1病例资料患者,男,74岁。2018年5月22日因腰部不适于当地诊所针灸治疗,4 d后出现发热,伴畏寒,四肢肿胀,自服退热药,效果不佳,体温升至39℃,四肢肿
引文
[1]姚咏明,盛志勇.重视金黄色葡萄球菌脓毒症的研究[J].中华烧伤杂志,2000,16(2):75-77.
[2]Keynan Y,Rubinstein E.staphylococcus aureus bacteremia,risk factors,complication,and management[J].Crit Care Clin,2013,29:547-562.
[3]White A.A cumulative review of the range and incidence of significant adverse events associated with acupunctue[J].Acupunct Med,2004,22:122-133.
[4]Jung N.Rieg S.Essentials in the management of S.aureus bloodstream infection[J].Infection,2018,46(4):441-442.
[5]江琰笛,张恩,陶崑.关节腔感染病原菌分布及耐药性分析[J].中国卫生检验杂志,2018,18(13):1541-1543.
[6]邱海波,施毅.耐药革兰阳性球菌感染诊疗手册[M].北京:人民卫生出版社,2018:196-200.
[7]范洪伟.热病(第46版)[M].北京:中国协和医科大学出版社,2017:33.
[8]马小军,徐英春,刘正印.ABX指南(第2版)[M].北京:科学技术文献出版社,2012:10-12.
[9]黄仲义.利奈唑胺在临床治疗中的药代动力学和药效学[J].中华内科杂志,2013,52(3):251-253.
[10]Osmon DR,Berbari EF,Berendt AR,et al.Executive summary:diagnosis and management of prosthetic joint infection:clinical practice guidelines by the Infectious Diseases Society of America[J].Clin Infect Dis,2013,56(1):1-10.
[11]Murdoch DR,Roberts SA,Fowler VG jr,et al.Infection of orthopedic prostheses after staphylococcus aureus bacteremia[J].Clin Infect Dis,2001,32:647-649.
[12]张先龙,沈灏,王加兴.人工关节假体感染诊治的研究进展[J].中华关节外科杂志,2017,11(4):327-330.
[13]Chiang GS,Tong K.Acupuncture causing methicillin-sensitive Staphylococcus aureus spondylodiscitis resulting in bacteremia and bacteriuria[J].J Am Geriatr Soc,2014,62(11):2221-2222.
[14]范俊,兰汀隆,董伟杰,等.金黄色葡萄球菌性脊柱炎的临床诊断与手术治疗[J].中国防痨杂志,2014,40(5):455-461.
[15]Pène F,Pickkers P,Hotchkiss RS.Is this critically ill patient immunocompromised?[J]Intensive Care Med,2016,42(6):1051-1054.
[16]汤艳清,谢光荣,李艳苓.抑郁症患者血中T细胞亚群数量及相关因素的研究[J].中国临床心理学杂志,2004,12(3):279-283.
[17]Wu J,Zhou L,Liu J,et al.The efficacy of thymosin alpha 1 for severe sepsis(ETASS):a multicenter,single-blind,randomized and controlled trial[J].Crit Care,2013,17(1):47-53.
[18]姚咏明,张艳敏.脓毒症发病机制最新认识[J].医学研究生学报,2017,30(7):678-683.
[19]马晓春,王亮.Sepsis 1.0到Sepsis 3.0的变迁与展望[J].医学研究生学报,2017,30(10):1009-1012.
[2]Keynan Y,Rubinstein E.staphylococcus aureus bacteremia,risk factors,complication,and management[J].Crit Care Clin,2013,29:547-562.
[3]White A.A cumulative review of the range and incidence of significant adverse events associated with acupunctue[J].Acupunct Med,2004,22:122-133.
[4]Jung N.Rieg S.Essentials in the management of S.aureus bloodstream infection[J].Infection,2018,46(4):441-442.
[5]江琰笛,张恩,陶崑.关节腔感染病原菌分布及耐药性分析[J].中国卫生检验杂志,2018,18(13):1541-1543.
[6]邱海波,施毅.耐药革兰阳性球菌感染诊疗手册[M].北京:人民卫生出版社,2018:196-200.
[7]范洪伟.热病(第46版)[M].北京:中国协和医科大学出版社,2017:33.
[8]马小军,徐英春,刘正印.ABX指南(第2版)[M].北京:科学技术文献出版社,2012:10-12.
[9]黄仲义.利奈唑胺在临床治疗中的药代动力学和药效学[J].中华内科杂志,2013,52(3):251-253.
[10]Osmon DR,Berbari EF,Berendt AR,et al.Executive summary:diagnosis and management of prosthetic joint infection:clinical practice guidelines by the Infectious Diseases Society of America[J].Clin Infect Dis,2013,56(1):1-10.
[11]Murdoch DR,Roberts SA,Fowler VG jr,et al.Infection of orthopedic prostheses after staphylococcus aureus bacteremia[J].Clin Infect Dis,2001,32:647-649.
[12]张先龙,沈灏,王加兴.人工关节假体感染诊治的研究进展[J].中华关节外科杂志,2017,11(4):327-330.
[13]Chiang GS,Tong K.Acupuncture causing methicillin-sensitive Staphylococcus aureus spondylodiscitis resulting in bacteremia and bacteriuria[J].J Am Geriatr Soc,2014,62(11):2221-2222.
[14]范俊,兰汀隆,董伟杰,等.金黄色葡萄球菌性脊柱炎的临床诊断与手术治疗[J].中国防痨杂志,2014,40(5):455-461.
[15]Pène F,Pickkers P,Hotchkiss RS.Is this critically ill patient immunocompromised?[J]Intensive Care Med,2016,42(6):1051-1054.
[16]汤艳清,谢光荣,李艳苓.抑郁症患者血中T细胞亚群数量及相关因素的研究[J].中国临床心理学杂志,2004,12(3):279-283.
[17]Wu J,Zhou L,Liu J,et al.The efficacy of thymosin alpha 1 for severe sepsis(ETASS):a multicenter,single-blind,randomized and controlled trial[J].Crit Care,2013,17(1):47-53.
[18]姚咏明,张艳敏.脓毒症发病机制最新认识[J].医学研究生学报,2017,30(7):678-683.
[19]马晓春,王亮.Sepsis 1.0到Sepsis 3.0的变迁与展望[J].医学研究生学报,2017,30(10):1009-1012.