竹叶石膏汤合清气化痰丸治疗COPD的疗效
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摘要
目的观察竹叶石膏汤合清气化痰丸加减治疗COPD的疗效。方法选取2016年6月—2017年6月接受治疗的100例急性加重期COPD患者,按随机数字表法分成观察组与对照组各50例。对照组接受常规综合治疗,观察组除同对照组的治疗方法外,还加用竹叶石膏汤合清气化痰丸加减方。对比2组患者治疗前后病情严重程度、呼吸困难程度、中医证候情况及临床治疗总体效果。结果治疗后,2组患者mMRC、CAT及中医证候评分均明显减少,且观察组各项评分均明显小于对照组(P<0.05),总有效率明显高于对照组(P<0.05)。结论竹叶石膏汤合清气化痰丸加减治疗急性加重期慢性阻塞性肺疾病的疗效显著,值得临床推广。
Objective To observe the curative effect of Zhuye Shigao decoction combined with Qingqi Huatan pills in the treatment of COPD. Methods 100 patients with acute exacerbation chronic obstructive pulmonary disease were selected from June 2016 to June2017 in our hospital. They were divided into observation group and control group by random number table. Patients in the control group received routine comprehensive treatment; patients in the observation group, in addition to the same control group, but also add Zhuye Shigao decoction combined with Qingqi Huatan pills. The severity of illness, dyspnea, symptoms of traditional Chinese medicine and the overall effect of clinical treatment were compared between the two groups before and after treatment. Results After treatment, the scores of mMRC, CAT and TCM symptoms of the two groups were significantly reduced, and the scores of the observation group were significantly lower than those of the control group( P < 0.05); the total effective rate was significantly higher than that of the control group(P < 0.05). Conclusion Zhuye Shigao decoction combined with Qingqi Huatan pills in the treatment of acute exacerbation of chronic obstructive pulmonary disease has a significant effect, worthy of clinical promotion.
Objective To observe the curative effect of Zhuye Shigao decoction combined with Qingqi Huatan pills in the treatment of COPD. Methods 100 patients with acute exacerbation chronic obstructive pulmonary disease were selected from June 2016 to June2017 in our hospital. They were divided into observation group and control group by random number table. Patients in the control group received routine comprehensive treatment; patients in the observation group, in addition to the same control group, but also add Zhuye Shigao decoction combined with Qingqi Huatan pills. The severity of illness, dyspnea, symptoms of traditional Chinese medicine and the overall effect of clinical treatment were compared between the two groups before and after treatment. Results After treatment, the scores of mMRC, CAT and TCM symptoms of the two groups were significantly reduced, and the scores of the observation group were significantly lower than those of the control group( P < 0.05); the total effective rate was significantly higher than that of the control group(P < 0.05). Conclusion Zhuye Shigao decoction combined with Qingqi Huatan pills in the treatment of acute exacerbation of chronic obstructive pulmonary disease has a significant effect, worthy of clinical promotion.
引文
[1]侯守强,荣陶,杨秀军,等.急性加重期慢性阻塞性肺疾病患者肺功能损伤细胞因子的变化与莫西沙星治疗疗效分析[J].中华医院感染学杂志,2016,26(19):4425-4427.
[2]张海龙,王明航,李风雷,等.中医药辨证治疗急性加重期慢性阻塞性肺疾病随机对照试验疗效评价指标的系统评价[J].中医学报,2013,28(6):797-804.
[3] Xu N,Chen J,Chang X,et al. n CD64 index as a prognostic biomarker for mortality in acute exacerbation of chronic obstructive pulmonary disease[J].Annals of Saudi Medicine,2016,36(1):37-41.
[4]中华医学会呼吸病学分会慢性阻塞性肺疾病学组.慢性阻塞性肺疾病诊治指南[J].中华内科杂志,2002,41(9):640-646.
[5]中华中医药学会内科分会肺系病专业委员会.慢性阻塞性肺疾病中医证候诊断标准(2011版)[J].中医杂志,2012,53(2):177-178.
[6]杨秀云,杨中良,黄飞华,等.清气化痰汤结合西医治疗慢性阻塞性肺疾病急性加重期疗效和证候变化的Meta分析[J].中华中医药学刊,2016,34(4):860-863.
[7] Depp T B,Mcginnis K A,Kraemer K,et al. Risk factors associated with acute exacerbation of chronic obstructive pulmonary disease in HIV-infected and uninfected patients[J]. Aids,2016,30(3):455-463.
[8]侯宝君,牛泽波,谷书馨,等.围术期输血患者应用竹叶石膏汤加减对患者免疫功能影响的研究[J].湖南中医药大学学报,2016,36(A01):355-356.
[9] Badawy M,Mohamed L,Fathy A. Inflammatory markers in patients with acute exacerbation of chronic obstructive pulmonary disease and role of bacterial infection[J]. Chest,2017,152(4):A783.
[10]张文斌,雷文汇,冯英凯.竹叶石膏汤合清气化痰丸加减治疗急性加重期慢性阻塞性肺疾病[J].中国实验方剂学杂志,2017,23(11):190-195.
[2]张海龙,王明航,李风雷,等.中医药辨证治疗急性加重期慢性阻塞性肺疾病随机对照试验疗效评价指标的系统评价[J].中医学报,2013,28(6):797-804.
[3] Xu N,Chen J,Chang X,et al. n CD64 index as a prognostic biomarker for mortality in acute exacerbation of chronic obstructive pulmonary disease[J].Annals of Saudi Medicine,2016,36(1):37-41.
[4]中华医学会呼吸病学分会慢性阻塞性肺疾病学组.慢性阻塞性肺疾病诊治指南[J].中华内科杂志,2002,41(9):640-646.
[5]中华中医药学会内科分会肺系病专业委员会.慢性阻塞性肺疾病中医证候诊断标准(2011版)[J].中医杂志,2012,53(2):177-178.
[6]杨秀云,杨中良,黄飞华,等.清气化痰汤结合西医治疗慢性阻塞性肺疾病急性加重期疗效和证候变化的Meta分析[J].中华中医药学刊,2016,34(4):860-863.
[7] Depp T B,Mcginnis K A,Kraemer K,et al. Risk factors associated with acute exacerbation of chronic obstructive pulmonary disease in HIV-infected and uninfected patients[J]. Aids,2016,30(3):455-463.
[8]侯宝君,牛泽波,谷书馨,等.围术期输血患者应用竹叶石膏汤加减对患者免疫功能影响的研究[J].湖南中医药大学学报,2016,36(A01):355-356.
[9] Badawy M,Mohamed L,Fathy A. Inflammatory markers in patients with acute exacerbation of chronic obstructive pulmonary disease and role of bacterial infection[J]. Chest,2017,152(4):A783.
[10]张文斌,雷文汇,冯英凯.竹叶石膏汤合清气化痰丸加减治疗急性加重期慢性阻塞性肺疾病[J].中国实验方剂学杂志,2017,23(11):190-195.