苦玄参提取物对仔猪生长性能的影响研究
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摘要
[目的]试验旨在探讨苦玄参提取物对仔猪生长性能的影响,为其在动物生产中更好地应用提供参考依据。[方法]选取体重相近的28～35日龄杜×长×大三元杂交的健康断奶仔猪250头,随机分为5组(A、B、C、D、E组),每组设5个重复,每个重复10头。其中,A、B、C组依次为苦玄参提取物高、中、低3个剂量试验组,分别在基础日粮中添加3.500、1.750和0.875 g/kg苦玄参提取物;D组在基础日粮中添加对照药物七补散4.0 g/kg;E组为空白对照组,饲喂基础日粮,预饲期7 d,正试期30 d。于试验正式开始的第0天、第15天和第30天7:00分别对各组的每一头试验猪进行空腹称重,并每天记录每个组试验猪的采食量,计算平均日采食量(ADFI)、平均日增重(ADG)和料重比(F/G)。[结果]添加苦玄参提取物后,A、B、C组仔猪的体重、ADG及ADFI,与E组相比显著或极显著(P<0.05或P<0.01)增加,而料重比降低;其中苦玄参提取物中剂量组仔猪的体重、平均日增重及平均日采食量提升最明显,料重比也极显著低于D组与E组(P<0.01)。[结论]苦玄参提取物对仔猪生长具有一定的促进作用,以1.750 g/kg的添加剂量添加在饲料中效果最佳。
assess the effect of Picria fel-tarrae Lour.extracts on the growth performance of piglets and to provide a reference for their better application in animal production.total of 250 healthy three-way crossbred pigs(Duroc×Landrace×Yorkshire)aged 28 to 35 days with similar weight were selected and randomly divided into 5 groups(A-E)with 5replicates per treatment and 10 pigs per replicate.The groups of A,B and C were set as high-,middle-and low-dose Picria feltarrae Lour.extracts groups respectively,and fed diet with3.500,1.750 and 0.875 g/kg Picria fel-tarrae Lour.extracts,respectively.The group D was a positive medicine control group fed a diet containing 4.0 g/kg Qibusan.The group E was set as a blank control group fed basal diet.The prefeeding period was 7 days and the formal trial period lasted for 30 days.The experimental piglets in each group were weighed before feeding at 7:00 on the 0,15stand 17stday of the experiment,and the feed intake for each group were recorded.At the end of the experiment,the intergroup differences in average daily feed intake(ADFI),average daily gain(ADG)and feed to gain ratiowere statisticallyweight,ADG and ADFI of the groups of A,B and C were significantly or extremely significantly elevated compared to the group E(or),while the F/G was reduced.The group B(middledose group)showed the best performance in increasing the weight,ADG and ADFI of piglets and had extremely significantly lower F/G compared to the groups of D and E(P).fel-tarrae Lour.extracts have a certain growth promoting effect on piglets,and their optimal level of dietary supplementation was 1.750 g/kg.
assess the effect of Picria fel-tarrae Lour.extracts on the growth performance of piglets and to provide a reference for their better application in animal production.total of 250 healthy three-way crossbred pigs(Duroc×Landrace×Yorkshire)aged 28 to 35 days with similar weight were selected and randomly divided into 5 groups(A-E)with 5replicates per treatment and 10 pigs per replicate.The groups of A,B and C were set as high-,middle-and low-dose Picria feltarrae Lour.extracts groups respectively,and fed diet with3.500,1.750 and 0.875 g/kg Picria fel-tarrae Lour.extracts,respectively.The group D was a positive medicine control group fed a diet containing 4.0 g/kg Qibusan.The group E was set as a blank control group fed basal diet.The prefeeding period was 7 days and the formal trial period lasted for 30 days.The experimental piglets in each group were weighed before feeding at 7:00 on the 0,15stand 17stday of the experiment,and the feed intake for each group were recorded.At the end of the experiment,the intergroup differences in average daily feed intake(ADFI),average daily gain(ADG)and feed to gain ratiowere statisticallyweight,ADG and ADFI of the groups of A,B and C were significantly or extremely significantly elevated compared to the group E(or),while the F/G was reduced.The group B(middledose group)showed the best performance in increasing the weight,ADG and ADFI of piglets and had extremely significantly lower F/G compared to the groups of D and E(P).fel-tarrae Lour.extracts have a certain growth promoting effect on piglets,and their optimal level of dietary supplementation was 1.750 g/kg.
引文
[1]王磊,曹巍.全球抗生素耐药性现状分析及对策建议[J].军事医学,2017,41(5):329-333.
[2]LI L,ZHOU X,LI N,et al.Herbal drugs against cardiovascular disease:traditional medicine and modern development[J].Drug Discov Today,2015,20(9):1074-1086.
[3]国家药典委员会.中华人民共和国药典(2010年版)[M].北京:中国医药科技出版社,2010.
[4]ZHANG Y,WANG S,LI Y,et al.Sophocarpine and matrine inhibit the production of TNF-alpha and IL-6in murine macrophages and prevent cachexia-related symptoms induced by colon26 adenocarcinoma in mice[J].International Immunopharmacology,2008,8(13/14):1767-1772.
[5]陈君,甄汉深,韦建华.苦玄参叶抗炎药理作用研究[J].海峡药学,2013,25(2):23-25.
[6]KURD F,SAMAVATI V.Water soluble polysaccharides from Spirulina platensis:extraction and in vitro anti-cancer activity[J].International Journal of Biological Macromolecules,2015,74:498-506.
[7]康茜.两株华南毛蕨内生真菌及苦玄参抗菌活性成分的研究[D].广州:广东药科大学,2017.
[8]VODOVOTZ Y,CONSTANTINE G,FAEDER J,et al.Translational systems approaches to the biology of inflammation and healing[J].Immunopharmacol Immunotoxicol,2010,32(2):181-195.
[9]李萍,周芳,陈勇.苦玄参提取物解热作用的实验研究[J].时珍国医国药,2007,18(11):2638-2638.
[10]叶锦霞,梁日欣,王岚.氧化应激与心血管疾病的关系研究进展[J].中国实验方剂学杂志,2008,14(10):68-70.
[11]王奇志,陈雨,王鸣,等.苦草提取物Pft-d对小鼠S180肉瘤、肝癌Heps的抗癌作用及体外细胞毒活性实验研究[J].现代药物与临床,2010,25(2):134-137.
[12]杨翠,廖玉英,韦风英,等.苦玄参提取物对广西麻鸡生长性能及免疫器官指数的影响[J].粮食与饲料业,2016(9):53-56.
[13]秦秀霞.苦玄参药理研究进展[J].亚太传统医药,2014,10(2):41-42.
[14]吴建璋,文永新,黄永林,等.苦玄参提取物对小鼠的抗炎及镇痛作用[J].中国医院药学杂志,2012,32(16):1303-1304.
[15]杨翠,胡庭俊,杨剑,等.苦玄参提取物对广西麻鸡血清生化指标及免疫功能的影响[J].中国畜牧兽医,2017,44(1):65-73.
[16]魏建东.天然植物提取物对肉鸡生产性能、代谢性能和肠道健康影响的研究[D].泰安:山东农业大学,2012.
[17]王鹏.复方中草药对断奶仔猪生产性能、肠道酶活和免疫功能的影响[D].福州:福建农林大学,2012.
[18]易军,王晓明,张凤玲,等.当归提取物作为天然肠道吸收促进剂的应用:CN201410017214.X[P].2014-04-30.
[19]王浩,印遇龙,邓百川,等.植物提取物的特性及其在母猪生产中的应用[J].动物营养学报,2017,29(11):3852-3862.
[20]骆先虎,倪以祥.黄芪多糖对断奶仔猪生产性能的影响[J].中国饲料,2012(3):22-24.
[21]ZHAO X J,LI L,LUO Q L,et al.Effects of mulberry(Morus alba L.)leaf polysaccharides on growth performance,diarrhea,blood parameters,and gut microbiota of early-weanling pigs[J].Livestock Science,2015,177:88-94.
[22]汤平,李福宝,李健,等.复方中药制剂对断奶仔猪生长性能和腹泻率的影响[J].农技服务,2007(1):75-76.
[23]KNIGHT C D,KASSER T R,SWENSON G H,et al.The performance and carcass composition responses of finishing swine to a range of porcine somatotropin doses in a 1-week delivery system[J].Journal of Animal Science,1991,69(12):4678-4689.
[24]黄燕,肖艳芬,甄汉深,等.苦玄参体外抗菌作用的实验研究[J].广西中医药,2008,31(1):46-47.
[2]LI L,ZHOU X,LI N,et al.Herbal drugs against cardiovascular disease:traditional medicine and modern development[J].Drug Discov Today,2015,20(9):1074-1086.
[3]国家药典委员会.中华人民共和国药典(2010年版)[M].北京:中国医药科技出版社,2010.
[4]ZHANG Y,WANG S,LI Y,et al.Sophocarpine and matrine inhibit the production of TNF-alpha and IL-6in murine macrophages and prevent cachexia-related symptoms induced by colon26 adenocarcinoma in mice[J].International Immunopharmacology,2008,8(13/14):1767-1772.
[5]陈君,甄汉深,韦建华.苦玄参叶抗炎药理作用研究[J].海峡药学,2013,25(2):23-25.
[6]KURD F,SAMAVATI V.Water soluble polysaccharides from Spirulina platensis:extraction and in vitro anti-cancer activity[J].International Journal of Biological Macromolecules,2015,74:498-506.
[7]康茜.两株华南毛蕨内生真菌及苦玄参抗菌活性成分的研究[D].广州:广东药科大学,2017.
[8]VODOVOTZ Y,CONSTANTINE G,FAEDER J,et al.Translational systems approaches to the biology of inflammation and healing[J].Immunopharmacol Immunotoxicol,2010,32(2):181-195.
[9]李萍,周芳,陈勇.苦玄参提取物解热作用的实验研究[J].时珍国医国药,2007,18(11):2638-2638.
[10]叶锦霞,梁日欣,王岚.氧化应激与心血管疾病的关系研究进展[J].中国实验方剂学杂志,2008,14(10):68-70.
[11]王奇志,陈雨,王鸣,等.苦草提取物Pft-d对小鼠S180肉瘤、肝癌Heps的抗癌作用及体外细胞毒活性实验研究[J].现代药物与临床,2010,25(2):134-137.
[12]杨翠,廖玉英,韦风英,等.苦玄参提取物对广西麻鸡生长性能及免疫器官指数的影响[J].粮食与饲料业,2016(9):53-56.
[13]秦秀霞.苦玄参药理研究进展[J].亚太传统医药,2014,10(2):41-42.
[14]吴建璋,文永新,黄永林,等.苦玄参提取物对小鼠的抗炎及镇痛作用[J].中国医院药学杂志,2012,32(16):1303-1304.
[15]杨翠,胡庭俊,杨剑,等.苦玄参提取物对广西麻鸡血清生化指标及免疫功能的影响[J].中国畜牧兽医,2017,44(1):65-73.
[16]魏建东.天然植物提取物对肉鸡生产性能、代谢性能和肠道健康影响的研究[D].泰安:山东农业大学,2012.
[17]王鹏.复方中草药对断奶仔猪生产性能、肠道酶活和免疫功能的影响[D].福州:福建农林大学,2012.
[18]易军,王晓明,张凤玲,等.当归提取物作为天然肠道吸收促进剂的应用:CN201410017214.X[P].2014-04-30.
[19]王浩,印遇龙,邓百川,等.植物提取物的特性及其在母猪生产中的应用[J].动物营养学报,2017,29(11):3852-3862.
[20]骆先虎,倪以祥.黄芪多糖对断奶仔猪生产性能的影响[J].中国饲料,2012(3):22-24.
[21]ZHAO X J,LI L,LUO Q L,et al.Effects of mulberry(Morus alba L.)leaf polysaccharides on growth performance,diarrhea,blood parameters,and gut microbiota of early-weanling pigs[J].Livestock Science,2015,177:88-94.
[22]汤平,李福宝,李健,等.复方中药制剂对断奶仔猪生长性能和腹泻率的影响[J].农技服务,2007(1):75-76.
[23]KNIGHT C D,KASSER T R,SWENSON G H,et al.The performance and carcass composition responses of finishing swine to a range of porcine somatotropin doses in a 1-week delivery system[J].Journal of Animal Science,1991,69(12):4678-4689.
[24]黄燕,肖艳芬,甄汉深,等.苦玄参体外抗菌作用的实验研究[J].广西中医药,2008,31(1):46-47.