面向超导心磁图仪应用的环境评估方法
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摘要
无屏蔽低温超导心磁图仪在临床应用推进中逐渐凸显环境适应性问题,需要对安装地点进行全面的电磁环境和地坪震动评估。通过分析心磁图仪系统理论输出模型和已具备的噪声抑制手段,低频的环境磁场和震动仍是系统输出的重要干扰因素。采用磁通门梯度计和加速度计,基于LabVIEW平台研制开发环境监测系统,实地获取应用环境的磁场、磁场梯度和地坪震动信息,通过分析采样数据的时域、频域特征和样本统计分布特征,优选出符合条件的场地,目前已完成两家医院选址评估。心磁系统环境噪声采样经多周期平均处理后优于2.5 pT,满足心磁采样要求,目前两家医院累计完成临床心磁采样700余例。结果表明,此环境评估方法将有助于加速心磁图仪应用推广和国内首个心磁数据库的筹建。
The environmental adaptability problem gradually emerges in the advancement of clinical applications of the unshielded low-temperature superconducting magnetocardiography(MCG),so it is necessary to conduct comprehensive evaluation of electromagnetic environment and ground vibration for installation sites. It is found that the low-frequency environment magnetic field and vibration are considered as the important interference factors of the system output by analyzing the theoretical output model of the MCG system and the available noise suppression methods. The environment monitoring system is developed on the basis of the LabVIEW platform by using the fluxgate gradiometer and accelerometer to obtain the information of magnetic field,magnetic field gradient and ground vibration in the application environment on site. The sites in accordance with the conditions are optimally selected by analyzing the time domain and frequency domain characteristics of the sampling data,and sample statistical distribution characteristics. The site selection assessment of two hospitals has been completed up to now. The environmental noise sampling of the MCG system after multi-period average processing is better than 2.5 pT,which can satisfy the MCG sampling requirement. More than 700 cases of clinical MCG sampling have been completed in the two hospitals up to now. The results show that the environmental assessment method can help speed up the application and promotion of the MCG and the preparation of the first MCG database in China.
The environmental adaptability problem gradually emerges in the advancement of clinical applications of the unshielded low-temperature superconducting magnetocardiography(MCG),so it is necessary to conduct comprehensive evaluation of electromagnetic environment and ground vibration for installation sites. It is found that the low-frequency environment magnetic field and vibration are considered as the important interference factors of the system output by analyzing the theoretical output model of the MCG system and the available noise suppression methods. The environment monitoring system is developed on the basis of the LabVIEW platform by using the fluxgate gradiometer and accelerometer to obtain the information of magnetic field,magnetic field gradient and ground vibration in the application environment on site. The sites in accordance with the conditions are optimally selected by analyzing the time domain and frequency domain characteristics of the sampling data,and sample statistical distribution characteristics. The site selection assessment of two hospitals has been completed up to now. The environmental noise sampling of the MCG system after multi-period average processing is better than 2.5 pT,which can satisfy the MCG sampling requirement. More than 700 cases of clinical MCG sampling have been completed in the two hospitals up to now. The results show that the environmental assessment method can help speed up the application and promotion of the MCG and the preparation of the first MCG database in China.
引文
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[2]LI Y,CHE Z,QUAN W,et al.Diagnostic outcomes of magnetocardiography in patients with coronary artery disease[J].International journal of clinical and experimental medicine,2015,8(2):2441-2446.
[3]YOSHIDA K,OGATA K,INABA T,et al.Ability of magnetocardiography to detect regional dominant frequencies of atrial fibrillation[J].Journal of arrhythmia,2015,31(6):345-351.
[4]孙慧娜,唐发宽,黄骁,等.心磁图的主要临床应用及研究进展[J].中国循证心血管医学杂志,2014,6(4):499-500.SUN Huina,TANG Fakuan,HUANG Xiao,et al.The main clinical application and research progress of magnetocardiography[J].Chinese journal of evidence-based cardiovascular medicine,2014,6(4):499-500.
[5]周志文,郑宏超,缪培智,等.心磁图在冠心病和心律失常中的研究进展[J].中国心血管杂志,2016,21(1):60-64.ZHOU Zhiwen,ZHENG Hongchao,MIAO Peizhi,et al.Progress of magnetocardiography in coronary artery disease and cardiac arrhythmias[J].Chinese journal of cardiovascular medicine,2016,21(1):60-64.
[6]ZHANG Y,WOLTERS N,SCHUBERT J,et al.HTS SQUIDgradiometer using substrate resonators operating in an unshielded environment:a portable MCG system[J].IEEE transactions on applied superconductivity,2003,13(2):389-392.
[7]KANG C S,LEE Y H,YU K K,et al.Measurement of MCGin unshielded environment using a second-order SQUID gradiometer[J].IEEE transactions on magnetics,2009,45(6):2882-2885.
[8]SHANEHSAZZADEH F,FARDMANESH M.Low noise active shield for SQUID-based magnetocardiography systems[J].IEEEtransactions on applied superconductivity,2018,28(4):205-208.
[9]陈亮,蒋式勤,谢晓明.超导梯度计及其对环境噪声的抑制能力[J].功能材料与器件学报,2008,14(6):971-976.CHEN Liang,JIANG Shiqin,XIE Xiaoming.Environmental noise cancellation of superconducting gradiometers[J].Journal of functional materials and devices,2008,14(6):971-976.
[10]KONG Xiangyan,ZHANG Shulin,WANG Yongliang,et al.Multi-channel magnetocardiogardiography system based on lowTc SQUIDs in an unshielded environment[J].Physics procedia,2012,36:286-292.
[11]张树林,张国峰,王永良,等.新型超导量子干涉器件在生物磁探测中的应用[J].科学通报,2013,58(21):2046-2048.ZHANG Shulin,ZHANG Guofeng,WANG Yongliang,et al.Application of a novel superconducting quantum interference device in biological magnetic detection[J].Chinese science bulletin,2013,58(21):2046-2048.
[12]陈科山,崔兴斌,陶冬,等.基于虚拟仪器的振动信号采集与处理系统[J].现代电子技术,2011,34(22):144-146.CHEN Keshan,CUI Xingbin,TAO Dong,et al.Vibration signal acquisition and processing system based on virtual instrument[J].Modern electronics technique,2011,34(22):144-146.
[13]谢冰,陈昌鑫,郑宾.基于LabVIEW的数据采集与信号处理系统设计[J].现代电子技术,2011,34(14):173-175.XIE Bing,CHEN Changxin,ZHENG Bin.Design of data acquisition and signal processing system based on LabVIEW[J].Modern electronics technique,2011,34(14):173-175.
[14]伍俊,荣亮亮,王永良,等.图形化系统设计平台在超导地球物理勘探中的应用研究[J].仪器仪表学报,2014,35(z1):21-26.WU Jun,RONG Liangliang,WANG Yongliang,et al.Application of graphical system design platform for superconducting geophysical exploration[J].Chinese journal of scientific instrument,2014,35(S1):21-26.
[15]李鑫,窦子优,马明,等.基于NI CompactRIO的多通道磁场采集系统的设计与实现[J].传感技术学报,2017,30(9):1447-1453.LI Xin,DOU Ziyou,MA Ming,et al.Design and implementation of multi channel magnetic field acquisition system based on NI CompactRIO[J].Chinese journal of sensors and actuators,2017,30(9):1447-1453.
[16]杨巧玉,娄良琼,杨立志.941B型超低频测振仪的研究[J].地震工程与工程振动,2005,25(4):174-179.YANG Qiaoyu,LOU Liangqiong,YANG Lizhi.Model 941Bultra-low frequency vibration gauge[J].Earthquake engineering and engineering vibration,2005,25(4):174-179.