新型纳米传感薄膜材料在发酵组分检测中的研究进展
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摘要
发酵工业目前缺少组分浓度实时监控技术以实现精确过程调控,因此,发酵用生物传感器逐渐受到该领域的重视。本文将关注发酵用生物传感器的最新研究进展,特别综述新型纳米传感材料在发酵组分检测中的最新研究成果,介绍在不同的发酵体系中纳米材料的设计及合成策略,包括贵金属、金属氧化物、配位化合物、有机化合物及碳基等各类纳米材料,简述这些纳米材料在发酵传感中的检测机理以及所开发的生物传感器在不同真实发酵液中的检测性能,从检测灵敏度、工作电位、抗干扰能力等方面系统地评价各类纳米材料在发酵环境中使用的优势和不足,分析发酵体系专用生物传感器材料的发展方向,为研发出可实现"多组分"及"宽检测范围"的发酵组分浓度检测技术提供重要的参考及借鉴。
Due to the lack of an efficient online monitor technology for the component concentration in the fermentation, more and more researches are working on the development of the fermentationbiosensors. This review mainly focuses on the recent research progresses on the fermentation biosensors,especially on the progress of the recent synthesized novel nanomaterials for the construction of thefermentation biosensor. The various nanomaterial design strategies and preparation methods have beenintroduced for the different fermentation systems, including metal, metal oxide, coordination compound,organic compound, and carbon based nanomaterials. The mechanisms of these nanomaterials and theirpractical biosensing performance were also discussed. According to the sensitivity, working potential and anti-inteference ability, the advantages and disadvantages of these materials were evaluated, and the future development of the biosensing materials for the fermentation detection had also been analyzed. The review provides an important reference to the biosensor fabrication for the wide range and multiple fermentation components detection.
Due to the lack of an efficient online monitor technology for the component concentration in the fermentation, more and more researches are working on the development of the fermentationbiosensors. This review mainly focuses on the recent research progresses on the fermentation biosensors,especially on the progress of the recent synthesized novel nanomaterials for the construction of thefermentation biosensor. The various nanomaterial design strategies and preparation methods have beenintroduced for the different fermentation systems, including metal, metal oxide, coordination compound,organic compound, and carbon based nanomaterials. The mechanisms of these nanomaterials and theirpractical biosensing performance were also discussed. According to the sensitivity, working potential and anti-inteference ability, the advantages and disadvantages of these materials were evaluated, and the future development of the biosensing materials for the fermentation detection had also been analyzed. The review provides an important reference to the biosensor fabrication for the wide range and multiple fermentation components detection.
引文
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[5] KIM S H, HAN S K, SHIN H S. Effect of substrate concentrationon hydrogen production and 16S rDNA-based analysis of themicrobial community in a continuous fermenter[J]. ProcessBiochemistry,2006,41(1):199-207.
[6] QURESHI N,SAHA B C,HECTOR R E,et al. Butanol productionfrom wheat straw by simultaneous saccharification andfermentation using Clostridium beijerinckii:Part—Batchfermentation[J]. Biomass and Bioenergy,2008,32(2):168-175.
[7] MEARS L,STOCKS S M,SIN G,et al. A review of controlstrategies for manipulating the feed rate in fed-batch fermentationprocesses[J]. Journal of Biotechnology,2017,245:34-46.
[8] BELLON-MAUREL V,ORLIAC O,CHRISTEN P. Sensors andmeasurements in solid state fermentation:a review[J]. ProcessBiochemistry,2003,38(6):881-896.
[9] KROMMENHOEK E E,VAN LEEUWEN M,GARDENIERS H,et al. Lab-scale fermentation tests of microchip with integratedelectrochemical sensors for pH, temperature, dissolved oxygen andviable biomass concentration[J]. Biotechnology&Bioengineering,2008,99(4):884-892.
[10] ALEXANDROPOULOU M,ANTONOPOULOU G,LYBERATOSG. A novel approach of modeling continuous dark hydrogenfermentation[J]. Bioresource Technology,2017,250:784.
[11] WANG J. Glucose biosensors:40 years of advances and challenges[J]. Electroanalysis,2010,13(12):983-988.
[12] GOODE J A,RUSHWORTH J V H,MILLNER P A. Biosensorregeneration:a review of common techniques and outcomes[J].Langmuir the ACS Journal of Surfaces&Colloids,2015,31(23):6267-6276.
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[14]张先恩.生物传感器[M].北京:化学工业出版社, 2006.ZHANG X E. Biosensor[M]. Beijing:Chemical Industry Press,2006.
[15] WANG J. Electrochemical glucose biosensors[J]. ChemicalReviews,2008,108:814-825.
[16] CHU Z Y,LIU Y,JIN W Q. Recent progress in Prussian bluefilms:methods used to control regular nanostructures forelectrochemical biosensing applications[J]. Biosensors&Bioelectronics,2017,96:17-25.
[17] LIU L F,SHI L,CHU Z Y,et al. Prussian blue nanocubesmodified graphite electrodes for the electrochemical detection ofvarious analytes with high performance[J]. Sensors and ActuatorsB:Chemical,2014,202:820-826.
[18] XU J J,ZHAO W,LUO X L,et al. A sensitive biosensor for lactatebased on layer-by-layer assembling MnO2nanoparticles andlactate oxidase on ion-sensitive field-effect transistors[J].Chemical Communications,2005,6(6):792-794.
[19] OZEL R E,ISPAS C,GANESANA M,et al. Glutamate oxidasebiosensor based on mixed ceria and titania nanoparticles for thedetection of glutamate in hypoxic environments[J]. Biosensors&Bioelectronics,2014,52:397-402.
[20] ZHANG L,XU Z,SUN X,et al. A novel alcohol dehydrogenasebiosensor based on solid-state electrogenerated chemiluminescenceby assembling dehydrogenase to Ru(bpy)32+Au nanoparticlesaggregates[J]. Biosensors&Bioelectronics,2007,22(6):1097-1100.
[21] TSAI Y C,HUANG J D,CHIU C C. Amperometric ethanolbiosensorbasedonpoly(vinylalcohol)-multiwalledcarbonnanotube-alcohol dehydrogenase biocomposite[J]. Biosensors&Bioelectronics,2007,22(12):3051-3056.
[22] KUMAR G S,WEE Y,LEE I,et al. Stabilized glyceroldehydrogenase for the conversion of glycerol to dihydroxyacetone[J]. Chemical Engineering Journal,2015,276:283-288.
[23] ZHANG H,XU Z,SHEN J,et al. Effects and mechanism ofatmospheric-pressure dielectric barrier discharge cold plasma onlactate dehydrogenase(LDH)enzyme[J]. Scientific Reports,2015,5:10031.
[24] VARGAS E,CONZUELO F,RUIZ M,et al. Automatedbioanalyzer based on amperometric enzymatic biosensors for thedetermination of ethanol in low-alcohol beers[J]. Beverages,2017,3(4):22.
[25] WANG L,TAO T,SU W,et al. A disease model of diabeticnephropathy in a glomerulus-on-a-chip microdevice[J]. Lab on AChip,2017,17(10):1749-1760.
[26] CHU Z Y,LI L L,LIU G P,et al. A novel membrane withheterogeneously functionalized nanocrystal layers performingblood separation and sensing synchronously[J]. Chemical-ⅠCommunications,2016,52(86):12706-12709.
[27] LIANG B,GUO X,FANG L,et al. Study of direct electron transferand enzyme activity of glucose oxidase on graphene surface[J].Electrochemistry Communications,2015,50:1-5.
[28] CHU Z Y,PENG J M,JIN W Q. Advanced nanomaterial inks forscreen-printed chemical sensors[J]. Sensors and Actuators B:Chemical,2017,243:919-926.
[29] GUERRIERI A,LATTANZIO V,PALMISANO F,et al.Electrosynthesized poly(pyrrole)/poly(2-naphthol)bilayermembrane as an effective anti-interference layer for simultaneousdetermination of acethylcholine and choline by a dual electrodeamperometric biosensor[J]. Biosensors&Bioelectronics,2006,21(9):1710-1718.
[30] EGGINS B R. Chemical sensors and biosensors[M]. New York:John Wiley&Sons,2008.
[31] COOPER J,CASS T. Biosensors[M]. New York:Oxford UniversityPress,2004.
[32] TRIPATHI V S,KANDIMALLA V B,JU H. Amperometricbiosensor for hydrogen peroxide based on ferrocene-bovine serumalbumin and multiwall carbon nanotube modified ormosilcomposite[J]. Biosensors and Bioelectronics,2006,21(8):1529-1535.
[33] LIU Y,CHU Z Y,JIN W Q. A sensitivity-controlled hydrogenperoxide sensor based on self-assembled Prussian blue modifiedelectrode[J]. Electrochemistry Communications,2009,11(2):484-487.
[34] JIA J,WANG B,WU A,et al. A method to construct a third-generation horseradish peroxidase biosensor:self-assembling goldnanoparticles to three-dimensional sol-gel network[J]. AnalyticalChemistry,2002,74(9):2217-2223.
[35] SOLANKI P R,KAUSHIK A,AGRAWAL V V,et al.Nanostructured metal oxide biosensors[J]. NPG AsiaMaterials,2011,3(1):17.
[36] HUYNH T P,SHARMA P S,SOSNOWSKA M,et al.Functionalized polythiophenes:recognition materials forchemosensors and biosensors of superior sensitivity, selectivity,and detectability[J]. Progress in Polymer Science,2015,47:1-25.
[37] CHAN D,BARSAN M M,KORPAN Y,et al. L-lactate selectiveimpedimetric bienzymatic biosensor based on lactatedehydrogenase and pyruvate oxidase[J]. Electrochimica Acta,2017,231:209-215.
[38] ARYA S K,SAHA S,RAMIREZ-VICK J E,et al. Recentadvances in ZnO nanostructures and thin films for biosensorapplications[J]. Analytica Chimica Acta,2012,737:1-21.
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