精神分裂症患者社会功能与复发关系的研究
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摘要
目的探讨在非干预条件下精神分裂症患者出院后3年的复发率以及社会功能,分析精神分裂症复发的影响因素。方法回顾性分析我院2011年9月至2012年8月"痊愈"出院的420例精神分裂症患者的临床资料。结果 420例出院患者中,3年复发率为58.1%,第1、 2、 3年的工作/学习、人际交往、自我照料均保持良好的患者分别占55.4%、 60.6%、 66.4%。Logistic回归分析显示,良好的工作/学习、人际交往是复发的保护因素(OR分别为2.611～5.714, 2.653～3.413; P <0.05)。结论精神分裂症患者出院后的社会功能较差,坚持工作/学习、维持人际交往有利于减少病情的复发。
Objective To explore the relapse rate and social function of schizophrenic patients 3 years after discharge under non-interventional conditions, and to analyze the influencing factors of schizophrenic relapse. Methods The clinical data of 420 cases of schizophrenic patients discharged from our hospital from September 2011 to August 2012 were retrospectively analyzed. Results Among420 cases of discharged patients, the 3-year relapse rate was 58.1%. The rates of maintaining good work or study, interpersonal communication and self care at the first, second and third year accounted for 55.4%, 60.6% and 66.4%. Logistic linear regression analysis showed that the good work or study and interpersonal communication were the protective factors for relapse(OR = 2.611 ～ 5.714, 2.653 ～3.413; P <0.05). Conclusions Schizophrenic patients have poor social function. Remaining work or study and interpersonal communication helps to reduce the relapse.
Objective To explore the relapse rate and social function of schizophrenic patients 3 years after discharge under non-interventional conditions, and to analyze the influencing factors of schizophrenic relapse. Methods The clinical data of 420 cases of schizophrenic patients discharged from our hospital from September 2011 to August 2012 were retrospectively analyzed. Results Among420 cases of discharged patients, the 3-year relapse rate was 58.1%. The rates of maintaining good work or study, interpersonal communication and self care at the first, second and third year accounted for 55.4%, 60.6% and 66.4%. Logistic linear regression analysis showed that the good work or study and interpersonal communication were the protective factors for relapse(OR = 2.611 ～ 5.714, 2.653 ～3.413; P <0.05). Conclusions Schizophrenic patients have poor social function. Remaining work or study and interpersonal communication helps to reduce the relapse.
引文
[1]王林平,邹义壮,谢孟杰.精神分裂症患者的前瞻性记忆与社会功能[J].中国心理卫生杂志, 2013, 27(8):619-623.
[2]刘军军,邵阿林,吴兵,等.长期住院的男性精神分裂症患者认知功能与社会功能研究[J].临床精神医学, 2016, 26(1):38-40.
[3] Wu FC, Huang YY, Zhou YL, et al. Factors influencing relapse in schizophrenia:a longitudinal study in China[J]. Biomed Res, 2017,28(9):4076-4082.
[4]朱文静,陈致宇,朱丞,等.经典与非经典抗精神病药对精神分裂症患者社会功能影响的5年随访[J].临床精神医学, 2017, 27(1):32-34.
[5] Hough D, Gopal S, Vijapurkar U, et al. Paliperidone palmitate maintenance treatment in delaying the time-to-relapse in patients with schizophrenia:a randomized, double-blind, placebo-controlled study[J]. Schizophr Res, 2010, 116(2-3):107-117.
[6] Yalincetin B, Ulas H, Var L, et al. Relation of formal thought disorder to symptomatic remission and social functioning in schizophrenia[J].Compr Psychiatry, 2016, 70(2):98-104.
[7] Harvey PD. Disability in schizophrenia:contributing factors and validated assessments[J]. J Clin Psychiatry, 2014, 75(1):15-20.
[8]吴逢春,周燕玲,郑英君,等.精神分裂症患者出院后1年复发情况及服药依从性的调查[J].广东医学, 2014, 35(1):130-132.
[9] Bae SM, Lee SH, Park YM, et al. Predictive factors of social functioning in patients with schizophrenia:exploration for the best combination of variables using data mining[J]. Psychiatry Investig, 2010, 7(2):93-101.
[10]屈金莲,张涛,宋杰,等.出院后精神分裂症患者服药依从性电话和短信干预的1年随访[J].中国心理卫生杂志, 2015, 29(9):656-661.
[2]刘军军,邵阿林,吴兵,等.长期住院的男性精神分裂症患者认知功能与社会功能研究[J].临床精神医学, 2016, 26(1):38-40.
[3] Wu FC, Huang YY, Zhou YL, et al. Factors influencing relapse in schizophrenia:a longitudinal study in China[J]. Biomed Res, 2017,28(9):4076-4082.
[4]朱文静,陈致宇,朱丞,等.经典与非经典抗精神病药对精神分裂症患者社会功能影响的5年随访[J].临床精神医学, 2017, 27(1):32-34.
[5] Hough D, Gopal S, Vijapurkar U, et al. Paliperidone palmitate maintenance treatment in delaying the time-to-relapse in patients with schizophrenia:a randomized, double-blind, placebo-controlled study[J]. Schizophr Res, 2010, 116(2-3):107-117.
[6] Yalincetin B, Ulas H, Var L, et al. Relation of formal thought disorder to symptomatic remission and social functioning in schizophrenia[J].Compr Psychiatry, 2016, 70(2):98-104.
[7] Harvey PD. Disability in schizophrenia:contributing factors and validated assessments[J]. J Clin Psychiatry, 2014, 75(1):15-20.
[8]吴逢春,周燕玲,郑英君,等.精神分裂症患者出院后1年复发情况及服药依从性的调查[J].广东医学, 2014, 35(1):130-132.
[9] Bae SM, Lee SH, Park YM, et al. Predictive factors of social functioning in patients with schizophrenia:exploration for the best combination of variables using data mining[J]. Psychiatry Investig, 2010, 7(2):93-101.
[10]屈金莲,张涛,宋杰,等.出院后精神分裂症患者服药依从性电话和短信干预的1年随访[J].中国心理卫生杂志, 2015, 29(9):656-661.