儿童白血病的环境危险因素分析
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摘要
白血病是儿童最常见的恶性肿瘤,目前世界范围内针对儿童白血病病因学机制尚不明确,但学者们普遍认为儿童白血病的发病机制是由环境、生物及遗传因素三者共同作用的结果。因此,对儿童白血病的环境危险因素的深入研究,对于儿童白血病的临床防治具有重要意义。
Leukemia is the most common malignancy in children,currently world-wide the machanism for the etiology of childhood leukemia is not clear,but scholars generally believe that the onset of childhood leukemia is the result of environmental,biological and genetic factors combined effect of the three. Therefore,in- deoth research on environmental risk factors for childhood leukemia,for the prevention and treatment of childhood leukemia clinical significance.
Leukemia is the most common malignancy in children,currently world-wide the machanism for the etiology of childhood leukemia is not clear,but scholars generally believe that the onset of childhood leukemia is the result of environmental,biological and genetic factors combined effect of the three. Therefore,in- deoth research on environmental risk factors for childhood leukemia,for the prevention and treatment of childhood leukemia clinical significance.
引文
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[14]李佳丽,曾东风,孔佩艳,等.重庆市125例儿童白血病发病危险因素的病例对照研究[J].第三军医大学学报,2012,34(9):888-892.
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[23]郑唯,周颖,屈卫东,等.五氯酚暴露与肿瘤风险关系的Meta分析[J].卫生研究,2008,37(2):151-154.
[24]ORTON F,LUTZ I,KLOAS W,et al.Endocrine disrupting effects of herbiicides and pentachlorophenol:in vitro and in vivo evidence[J].Environ Sci Technol,2009,43 6):2 144-2 150.
[25]宋瑞霞,阮鸿洁,刘征涛.五氯酚钠致突变性研究[J].中国公共卫生,2008,24(3):337-339.
[26]尹晓晨,曾明,王春香,等.五氯酚钠对雄性小鼠的生殖毒性作用[J].生态毒理学报,2008,3(5):473-478.
[27]阮鸿洁,景欣月,刘征涛,等.五氯酚钠的致敏性及其对DNA的损伤[J].中国卫生检验杂志,2010(5):1 049-1 050.
[28]吴兆毅,胡平,赵庆顺,等.利用基因芯片探讨五氯酚发育毒性的作用机制[J].环境科学,2009,30(11):3 382-3 387.
[29]Rudant J,Menegaux F,Leverger G,et al.Childhood hematopoietic malignancies and parental use of tobacco and alcohol:the ESCALE study(SFCE)[J].Cancer Causes Control,2008,19(10):1 277-1 290.
[30]Abdul Rahman HI,Shah SA,Alias H,et al.A case-control study on the association between environmental factors and the occurrence of acute leukemia among children in Klang Valley,Malaysia[J].Asian Pac J Cancer Prev,2008,9(4):649-652.
[31]Lee KM,Ward MH,Han S,et al.Paternal smoking,genetic polymorphisms in CYP1A1 and childhood leukemia risk[J].Leukemia Res,2009,33(2):250-258.
[32]Ou SX,Han D,Severson RK,et al.Birth characteristics,maternalreproductive history,hormonr use during pregnancy,and risk of childhood acute lymphocytic leukemia by immunophenotype(United States)[J].CancerCausesContro,2002,13(1):15-25.
[33]Severson RK,Ou SX,Han D.Birth characteristies,maternal reproductive history,hormone use during pregnancy,and risk childhood acute lymphocytic leukemia by immunophenotype(United States)[J].Cancer Causes Control,2002,13(l):15-20.
[34]吴丕六,戴碧涛,余忠红,等.儿童白血病致病危险因素分析[J].中国循证医学杂志,2010,10(9):1 037-1 040.
[35]王路敏.儿童白血病生物学特征的临床调查分析[D].山东:山东大学,2013.
[36]Bellec S,Baccaini B,Goubin A,et al.Childhood leukaemia and population movements in France,1990-2003[J].Br J Cancer,2008,98:225-231.
[2]Hjalgrim LL,RostgaardK,Schmiegelow K,et al.Age-and sex-specific incidenee of childhood leukemia by immunophenotype in the Nordic countries[J].J NatlCancer Inst,2003,95(20):539-543.
[3]Bailey HD,Milne E,de Klerk NH,et al.Exposure to house painting and the use of floor treatments and the risk of childhood acute lymphoblastic leukemia[J].Int J Cancer,2011,128(10):2 405-2 414.
[4]孙晓东,柴忆欢,曹幼甫,等.儿童白血病发病因素调查研究[J].中国航天医药杂志,2003,5(6):1-3.
[5]李涛,牛丽娟,李曼,等.居室内氡与白血病患病关系的Meta分析[J].临床荟萃,2007,22(11):797-798.
[6]郭新彪.机动车尾气污染的健康影响:亟待解决的重要公共卫生问题[J].环境与健康杂志,2009,(9):753-754.
[7]Weng HH,Tsai SS,Chen CC,et al.Childhood leukemia development and correlation with traffic air pollution in Taiwan using nitrogen dioxide as an air pollutant marker[J].J Toxicol Environ Health A,2008,71(7):434-438.
[8]Brosselin P,Rudant J,Orsil L,et al.Acute childhood leukaemia and residence next to petrol stations and auto-motive repair garages:the ESCALE study(SFCE)[J].Occup Environ Med,2009,66(9):598-606.
[9]Weng HH,Tsai SS,Chiu HF,et al.Association of childhood leukemia with residential exposure to petrochemical air pollution in Taiwan,Inhal[J].Toxico1,2008,20(1):31-36.
[10]Weng HH,Tsai SS,Chiu HF,et al.Childhood leukemia and traffic air pollution in Taiwan:petrol station density as an in-dicator[J].J Toxicol Environ Health A,2009,72(2):83-87.
[11]Whitworth KW,Symanski E,Cokcr AL.Childhood lymphohe matopoietic cancer incidence and hazardous air pollutants in southeast Texas,1995-2004[J].Environ Health Perspcet,2008,116(11):1 576-1 580.
[12]Von Bchren J,Reynolds P,Gunier RB,et al.Residential traffic density and childhood leukemia risk[J].Cancer Epidemiol Biomarkers Prev,2008,17(9):2 298-2 301.
[13]杜卫,孙立荣,刘青敏,等.儿童白血病相关危险因素研究[J].实用预防医学,2008,15(2):355-357.
[14]李佳丽,曾东风,孔佩艳,等.重庆市125例儿童白血病发病危险因素的病例对照研究[J].第三军医大学学报,2012,34(9):888-892.
[15]周炯林,徐培渝.有机磷农药遗传毒性研究进展[J].国外医学:卫生学分册,2007,34(6):339-344.
[16]MenegauxF,BaruchelA,BertrandY,et al.Household exposure to pesticides and risk ofchildhood acute leukaemia[J].OccupEnviron Med,2006,63(2):131-134.
[17]Axelson O,Fredrikson M,Kerblom G,et al.Leukemia in childhood and adolescence and exposure to ionizing radiation in homes built from uranium-containing alum shale concrete[J].Epidemiology,2002,13(2):146-150.
[18]Laurier D,Valenty M,Tirmarche M.Radon exposure and the risk of leukemia:a review of epidemiological studies[J].Health physics,2001,81(3):272-288.
[19]Infante-Rivard C,Mathonnet G,Sinnett D.Risk of childhood leukemia associated with diagnostic irradiation and polymorphisms in DNA repair genes[J].Environmental health perspectives,2000,108(6):495.
[20]Winker R,Ivancsits S,Pilger A,et al.Chromosomal damage in human diploid fibroblasts by intermittent exposure to extremely low-frequency electromagnetic fields[J].Mutation Research/Genetic Toxicology and Environmental Mutagenesis,2005,585(1):43-49.
[21]Feychting M,Floderus B,Ahlbom A.Parental occupational exposure to magnetic fields and childhood cancer(Sweden)[J].Cancer Causes&Control,2000,11(2):151-156.
[22]左锋,丁文清,潘小川,等.宁夏儿童白血病环境危险因素病例-对照研究[J].环境与健康杂志,2007;24(9):683-686.
[23]郑唯,周颖,屈卫东,等.五氯酚暴露与肿瘤风险关系的Meta分析[J].卫生研究,2008,37(2):151-154.
[24]ORTON F,LUTZ I,KLOAS W,et al.Endocrine disrupting effects of herbiicides and pentachlorophenol:in vitro and in vivo evidence[J].Environ Sci Technol,2009,43 6):2 144-2 150.
[25]宋瑞霞,阮鸿洁,刘征涛.五氯酚钠致突变性研究[J].中国公共卫生,2008,24(3):337-339.
[26]尹晓晨,曾明,王春香,等.五氯酚钠对雄性小鼠的生殖毒性作用[J].生态毒理学报,2008,3(5):473-478.
[27]阮鸿洁,景欣月,刘征涛,等.五氯酚钠的致敏性及其对DNA的损伤[J].中国卫生检验杂志,2010(5):1 049-1 050.
[28]吴兆毅,胡平,赵庆顺,等.利用基因芯片探讨五氯酚发育毒性的作用机制[J].环境科学,2009,30(11):3 382-3 387.
[29]Rudant J,Menegaux F,Leverger G,et al.Childhood hematopoietic malignancies and parental use of tobacco and alcohol:the ESCALE study(SFCE)[J].Cancer Causes Control,2008,19(10):1 277-1 290.
[30]Abdul Rahman HI,Shah SA,Alias H,et al.A case-control study on the association between environmental factors and the occurrence of acute leukemia among children in Klang Valley,Malaysia[J].Asian Pac J Cancer Prev,2008,9(4):649-652.
[31]Lee KM,Ward MH,Han S,et al.Paternal smoking,genetic polymorphisms in CYP1A1 and childhood leukemia risk[J].Leukemia Res,2009,33(2):250-258.
[32]Ou SX,Han D,Severson RK,et al.Birth characteristics,maternalreproductive history,hormonr use during pregnancy,and risk of childhood acute lymphocytic leukemia by immunophenotype(United States)[J].CancerCausesContro,2002,13(1):15-25.
[33]Severson RK,Ou SX,Han D.Birth characteristies,maternal reproductive history,hormone use during pregnancy,and risk childhood acute lymphocytic leukemia by immunophenotype(United States)[J].Cancer Causes Control,2002,13(l):15-20.
[34]吴丕六,戴碧涛,余忠红,等.儿童白血病致病危险因素分析[J].中国循证医学杂志,2010,10(9):1 037-1 040.
[35]王路敏.儿童白血病生物学特征的临床调查分析[D].山东:山东大学,2013.
[36]Bellec S,Baccaini B,Goubin A,et al.Childhood leukaemia and population movements in France,1990-2003[J].Br J Cancer,2008,98:225-231.