POEMS综合征误诊为慢性炎性脱髓鞘性多发性神经根神经病1例分析
摘要
<正>POEMS综合征是一种与浆细胞病有关的多系统病变,临床上以多发性神经病(polyneuropathy)、脏器肿大(organomegaly)、内分泌异常(endocrinopathy)、M蛋白血症(M-protein)或浆细胞瘤和皮肤病变(skin change)为特征。POEMS综合征缺乏特异性检测指标和病理学特征,临床上易与慢性炎性脱髓鞘性多发性神经根神经病(CIDP)、多发性骨髓瘤、糖尿病并发的末梢神经炎等疾病混淆,易造成误诊、漏
引文
[1] Cai Q Q,Wang C,Cao X X,et al.Efficacy and safety of lowdose lenalidomide plus dexamethasone in patients with relapsed or refractory POEMS syndrome[J].European Journal of Haematology,2015,95(4):325-330.
[2] Nozza A,Terenghi F,Gallia F,et al.Lenalidomide and dexamethasone in patients with POEMS syndrome:results of a prospective,open-label trial[J].British Journal of Haematology,2017,179(5):748-755.
[3] Dispenzieri A.POEMS syndrome:2017 Update on diagnosis,risk stratification,and management[J].American journal of hematology,2017,92(8):814-829.
[4] Wang C,Huang X F,Cai Q Q,et al.Remarkable expression of vascular endothelial growth factor in bone marrow plasma cells of patients with POEMS syndrome[J].Leukemia Research,2016,50:78-84.
[5] Misawa S,Sato Y,Katayama K,et al.Vascular endothelial growth factor as a predictive marker for POEMS syndrome treatment response:retrospective cohort study[J].BMJ Open,2015,5(11):e009157.
[6] 季丽莉,王钦,张雪皎,等.血清血管内皮生长因子在诊断 POEMS 综合征中的作用 (附2例报告)[J].中国临床神经科学,2016,24(3):288-293.
[7] Nasu S,Misawa S,Sekiguchi Y,et al.Different neurological and physiological profiles in POEMS syndrome and chronic inflammatory demyelinating polyneuropathy[J].J Neurol Neurosurg Psychiatry,2012,83(5):476-479.
[8] Piccione E A,Engelstad J,Dyck P J,et al.Nerve pathologic features differentiate POEMS syndrome from CIDP[J].Acta Neuropathologica Communications,2016,4(1):116.
[9] Li J,Zhou D B,Huang Z,et al.Clinical characteristics and long-term outcome of patients with POEMS syndrome in China[J].Annals of Hematology,2011,90(7):819-826.
[10] 周道斌,李剑.POEMS 综合征的诊断和治疗[J].中国肿瘤临床,2014,41(13):831-835.
[2] Nozza A,Terenghi F,Gallia F,et al.Lenalidomide and dexamethasone in patients with POEMS syndrome:results of a prospective,open-label trial[J].British Journal of Haematology,2017,179(5):748-755.
[3] Dispenzieri A.POEMS syndrome:2017 Update on diagnosis,risk stratification,and management[J].American journal of hematology,2017,92(8):814-829.
[4] Wang C,Huang X F,Cai Q Q,et al.Remarkable expression of vascular endothelial growth factor in bone marrow plasma cells of patients with POEMS syndrome[J].Leukemia Research,2016,50:78-84.
[5] Misawa S,Sato Y,Katayama K,et al.Vascular endothelial growth factor as a predictive marker for POEMS syndrome treatment response:retrospective cohort study[J].BMJ Open,2015,5(11):e009157.
[6] 季丽莉,王钦,张雪皎,等.血清血管内皮生长因子在诊断 POEMS 综合征中的作用 (附2例报告)[J].中国临床神经科学,2016,24(3):288-293.
[7] Nasu S,Misawa S,Sekiguchi Y,et al.Different neurological and physiological profiles in POEMS syndrome and chronic inflammatory demyelinating polyneuropathy[J].J Neurol Neurosurg Psychiatry,2012,83(5):476-479.
[8] Piccione E A,Engelstad J,Dyck P J,et al.Nerve pathologic features differentiate POEMS syndrome from CIDP[J].Acta Neuropathologica Communications,2016,4(1):116.
[9] Li J,Zhou D B,Huang Z,et al.Clinical characteristics and long-term outcome of patients with POEMS syndrome in China[J].Annals of Hematology,2011,90(7):819-826.
[10] 周道斌,李剑.POEMS 综合征的诊断和治疗[J].中国肿瘤临床,2014,41(13):831-835.