中医药防治新生儿喂养不耐受研究概况
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摘要
随着妇产技术的逐步提高,早产儿、低出生体质量儿等新生儿存活率逐年提升,喂养不耐受(Feeding Intolerance,FI)成为新生儿生长受限、发育迟缓的首要问题,如何合理解决其喂养问题,是提高早产儿、低出生体质量儿等新生儿存活率及生存质量的关键。目前西医学多采用胃肠动力药及肠道菌群调节剂治疗,方式单一,药物剂量难以控制,而近些年研究显示,中医药手段干预FI临床疗效较为显著,该文对中医药治疗FI的研究现状进行综述,探讨分析其病因病机、证治分型、临床用药等,挖掘其中医药治疗优势,拓展中医药治疗FI新思路,为FI的中医药治疗与研究提供参考和奠定基础。
With the gradual improvement of obstetrics and gynecology,the survival rate of premature babies,low birth weight infants and other newborns has increased year by year. Feeding Intolerance(FI)is the primary problem of growth retardation in newborns and how to solve the problem of feeding properly is the key to improve the survival rate and the quality of the newborns. At present,Western medicine usually used the single method of gastrointestinal motility drugs and intestinal flora modulators to treat FI,which the dosage of drugs is difficult to control. In recent years,research have shown that the therapeutic effect of traditional Chinese medicine in the intervention of FI is more significant. In this paper,the research status of traditional Chinese medicine in the treatment of FI is reviewed,and its etiology,pathogenesis,syndrome classification and clinical medication are discussed. This paper excavates the advantages of traditional Chinese medical treatment,expands the new thought of Chinese medicine treatment FI,and provides the reference and foundation for the treatment and research of traditional Chinese medicine of FI.
With the gradual improvement of obstetrics and gynecology,the survival rate of premature babies,low birth weight infants and other newborns has increased year by year. Feeding Intolerance(FI)is the primary problem of growth retardation in newborns and how to solve the problem of feeding properly is the key to improve the survival rate and the quality of the newborns. At present,Western medicine usually used the single method of gastrointestinal motility drugs and intestinal flora modulators to treat FI,which the dosage of drugs is difficult to control. In recent years,research have shown that the therapeutic effect of traditional Chinese medicine in the intervention of FI is more significant. In this paper,the research status of traditional Chinese medicine in the treatment of FI is reviewed,and its etiology,pathogenesis,syndrome classification and clinical medication are discussed. This paper excavates the advantages of traditional Chinese medical treatment,expands the new thought of Chinese medicine treatment FI,and provides the reference and foundation for the treatment and research of traditional Chinese medicine of FI.
引文
[1]李盛强,林丽妮,邓云森,等.音乐疗法对新生儿喂养不耐受保护作用的初步探讨[J].广州医药,2016,47(6):44-47.
[2]彭磊.红霉素不同给药方案对新生儿喂养不耐受比较[J].现代临床医学,2016,42(6):426-428.
[3]王妍,陈世耀,吴利俊.多潘立酮临床应用的系统评价[J].胃肠病学,2011,16(4):226-230.
[4]刘巧玉.四君子汤治疗早产儿喂养不耐受的临床研究[D].广州:广州中医药大学,2010.
[5]李海虹.加味四君子汤联合小剂量红霉素治疗早产儿喂养不耐受疗效观察[J].陕西中医,2016,37(11):1496-1498.
[6]李红光,黄军华,刘俊峰,等.四君子汤联合微量喂养对窒息后喂养不耐受新生儿血浆胃动素的影响[J].中国误诊学杂志,2011,11(13):3118-3119.
[7]王鉴,陈晓霞,王莉,等.早产儿胃肠功能与胃泌素、胃动素的相关性研究[J].贵阳医学院学报,2007(4):378-381.
[8]叶富强,陈蔚文.四君子汤对胃肠道作用的药理研究[J].时珍国医国药,2005,16(1):73-74.
[9]刘萍,黄承益,廖品东.廖品东教授推拿治疗新生儿喂养不耐受经验总结[J].中国民族民间医药,2016,25(24):67-68.
[10]刘卫红,王晓燕,王淇,等.四磨汤口服液治疗早产儿喂养不耐受的临床观察[J].中国误诊学杂志,2009(1):49-50.
[11]李建业,刘伟.四磨汤口服液干预早中期早产儿喂养不耐受83例临床观察[J].中医儿科杂志,2016,12(5):55-57.
[12]王洪波,张秋丽,周建国,等.四磨汤促进早产儿胃排空42例疗效观察[J].中医儿科杂志,2008(5):39-41.
[13]黄颖.四磨汤口服液对功能性消化不良大鼠胃排空及血浆胃肠激素的影响[D].广州:广州中医药大学,2011.
[14]滕建业.枳壳促进胃动力化学物质组的筛选及作用机理研究[D].沈阳:辽宁中医药大学,2011.
[15]王平.槟榔的促胃动力作用及其有效组分的探索[D].南京:南京医科大学,2012.
[16]聂子文.乌药“行气”功效物质基础研究[D].长沙:湖南中医药大学,2012.
[17]颜鹏飞.一捻金治疗新生儿喂养不耐受疗效观察[J].现代中西医结合杂志,2011,20(8):960-961.
[18]可喜来,燕小伟.一捻金胶囊联合乳果糖口服液治疗婴幼儿功能性便秘的临床研究[J].中医临床研究,2013,5(8):16-17.
[19]韩文鹤.推拿手法治疗小儿厌食的证治规律研究[D].成都:成都中医药大学,2012:21-27.
[20]朱琳.温中健脾类手法在小儿推拿中的应用[D].北京:北京中医药大学,2016.
[21]董洪英.健脾助运推拿法儿科应用[J].山东中医杂志,2009,28(7):504-505.
[22]张素芳.中国小儿推拿学[M].上海:上海中医学院出版社,1992:96.
[23]王文波.“摩腹揉脐,龟尾七节”简易推拿法治疗小儿腹泻120例[J].中国中医药现代远程教育,2011,9(8):52.
[24]靳永萍,刘芳丽,樊建科.穴位按摩在新生儿抚触中应用的效果评价[J].中国妇幼保健,2012,27(8):1237-1239.
[25]陈亦旋.小儿推拿在早产儿喂养不耐受的早期干预中的应用体会[J].现代诊断与治疗,2015,26(5):1093-1094.
[26]曹晓宽,李贵平,刘正希,等.足三里按摩与口服多潘立酮片治疗早产儿喂养不耐受的对照研究[J].内蒙古中医药,2017,36(10):125-126.
[27]姜永霞,程博,蒋松鹤,等.腰段夹脊穴的解剖学特征及其临床意义[J].中国针灸,2012,3(2):139-142.
[28]贾耿.督脉足太阳任脉肾精实质再探[J].中医药学刊,2003,21(11):1807-1808.
[29]田新霞.推拿治疗小儿单纯性消化不良220例观察[J].中国优生优育,2013,19(8):678-679.
[30]刘巧玉,张水堂,高立凡,等.小儿捏脊治疗早产儿喂养不耐受35例疗效观察[J].实用中西医结合临床,2011,11(6):46-47.
[31]李桂云,吴丽英.捏脊联合腹部按摩对早产儿喂养不耐受的影响[J].中国农村卫生,2015(13):73.
[2]彭磊.红霉素不同给药方案对新生儿喂养不耐受比较[J].现代临床医学,2016,42(6):426-428.
[3]王妍,陈世耀,吴利俊.多潘立酮临床应用的系统评价[J].胃肠病学,2011,16(4):226-230.
[4]刘巧玉.四君子汤治疗早产儿喂养不耐受的临床研究[D].广州:广州中医药大学,2010.
[5]李海虹.加味四君子汤联合小剂量红霉素治疗早产儿喂养不耐受疗效观察[J].陕西中医,2016,37(11):1496-1498.
[6]李红光,黄军华,刘俊峰,等.四君子汤联合微量喂养对窒息后喂养不耐受新生儿血浆胃动素的影响[J].中国误诊学杂志,2011,11(13):3118-3119.
[7]王鉴,陈晓霞,王莉,等.早产儿胃肠功能与胃泌素、胃动素的相关性研究[J].贵阳医学院学报,2007(4):378-381.
[8]叶富强,陈蔚文.四君子汤对胃肠道作用的药理研究[J].时珍国医国药,2005,16(1):73-74.
[9]刘萍,黄承益,廖品东.廖品东教授推拿治疗新生儿喂养不耐受经验总结[J].中国民族民间医药,2016,25(24):67-68.
[10]刘卫红,王晓燕,王淇,等.四磨汤口服液治疗早产儿喂养不耐受的临床观察[J].中国误诊学杂志,2009(1):49-50.
[11]李建业,刘伟.四磨汤口服液干预早中期早产儿喂养不耐受83例临床观察[J].中医儿科杂志,2016,12(5):55-57.
[12]王洪波,张秋丽,周建国,等.四磨汤促进早产儿胃排空42例疗效观察[J].中医儿科杂志,2008(5):39-41.
[13]黄颖.四磨汤口服液对功能性消化不良大鼠胃排空及血浆胃肠激素的影响[D].广州:广州中医药大学,2011.
[14]滕建业.枳壳促进胃动力化学物质组的筛选及作用机理研究[D].沈阳:辽宁中医药大学,2011.
[15]王平.槟榔的促胃动力作用及其有效组分的探索[D].南京:南京医科大学,2012.
[16]聂子文.乌药“行气”功效物质基础研究[D].长沙:湖南中医药大学,2012.
[17]颜鹏飞.一捻金治疗新生儿喂养不耐受疗效观察[J].现代中西医结合杂志,2011,20(8):960-961.
[18]可喜来,燕小伟.一捻金胶囊联合乳果糖口服液治疗婴幼儿功能性便秘的临床研究[J].中医临床研究,2013,5(8):16-17.
[19]韩文鹤.推拿手法治疗小儿厌食的证治规律研究[D].成都:成都中医药大学,2012:21-27.
[20]朱琳.温中健脾类手法在小儿推拿中的应用[D].北京:北京中医药大学,2016.
[21]董洪英.健脾助运推拿法儿科应用[J].山东中医杂志,2009,28(7):504-505.
[22]张素芳.中国小儿推拿学[M].上海:上海中医学院出版社,1992:96.
[23]王文波.“摩腹揉脐,龟尾七节”简易推拿法治疗小儿腹泻120例[J].中国中医药现代远程教育,2011,9(8):52.
[24]靳永萍,刘芳丽,樊建科.穴位按摩在新生儿抚触中应用的效果评价[J].中国妇幼保健,2012,27(8):1237-1239.
[25]陈亦旋.小儿推拿在早产儿喂养不耐受的早期干预中的应用体会[J].现代诊断与治疗,2015,26(5):1093-1094.
[26]曹晓宽,李贵平,刘正希,等.足三里按摩与口服多潘立酮片治疗早产儿喂养不耐受的对照研究[J].内蒙古中医药,2017,36(10):125-126.
[27]姜永霞,程博,蒋松鹤,等.腰段夹脊穴的解剖学特征及其临床意义[J].中国针灸,2012,3(2):139-142.
[28]贾耿.督脉足太阳任脉肾精实质再探[J].中医药学刊,2003,21(11):1807-1808.
[29]田新霞.推拿治疗小儿单纯性消化不良220例观察[J].中国优生优育,2013,19(8):678-679.
[30]刘巧玉,张水堂,高立凡,等.小儿捏脊治疗早产儿喂养不耐受35例疗效观察[J].实用中西医结合临床,2011,11(6):46-47.
[31]李桂云,吴丽英.捏脊联合腹部按摩对早产儿喂养不耐受的影响[J].中国农村卫生,2015(13):73.