乌鲁木齐市500例2型糖尿病患者抑郁症患病状况及其影响因素研究
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摘要
目的探讨乌鲁木齐市2型糖尿病患者合并抑郁症状况及其影响因素。方法采用横断面调查,对2016年12月1日~2017年4月30日在新疆医科大学第五附属医院内分泌科门诊就诊及住院部确诊的糖尿病患者开展问卷调查。采用Zung氏抑郁自评量表评价患者抑郁症患病情况。采用Logistic回归模型分析糖尿病发生抑郁症的影响因素。结果 500例糖尿病患者,其抑郁症患病率为20.00%,多元Logistic回归分析后结果显示:女性(与男性比较,OR=2.18,95%CI:1.49~3.19),维吾尔族(与汉族比较,OR=2.56,95%CI:1.17~5.57),离异/丧偶(与已婚比较,OR=1.74,95%CI:1.04~3.07)是糖尿病合并抑郁症的独立危险因素;大学文化程度及以上(与小学文化程度及以下比较,OR=0.38,95%CI:0.19~0.76),有家庭支持(与无家庭支持比较,OR=0.50,95%CI:0.28~0.91)是糖尿病合并抑郁症的保护因素。结论乌鲁木齐市糖尿病患者中抑郁症患病率较高,且与多种因素相关,诊疗时应及早筛查,及时干预,改善患者生活质量。
Objective To investigate the prevalence and predictors of depression among patients with diabetes mellitus in Wulumuqi,China. Methods A cross-sectional survey was conducted among patients diagnosed with diabetes in outpatient clinics and inpatients from December 1st,2016 to April 30th,2017 in Xinjiang Medical University the Fifth Affiliated Hospital. The depression status was screened using Zung's Self-Rating Depression Scale. Logistic regression model was used to analyze the predictors of depression among diabetic patients. Results The prevalence of depression was 20. 00% in 500 patients with diabetes mellitus. The results of logistic regression analysis showed that female( compared to male,OR = 2. 18,95% CI: 1. 49-3. 19) and Uyghur( compared to Han ethnic group,OR = 2. 56,95% CI: 1. 17-5. 57) divorced or widowed( compared to being married,OR = 1. 74,95% CI: 1. 04-3. 07) were independent risk factors of depression. Education level equal to or higher than college( compared to primary school and lower,OR = 0. 38,95% CI: 0. 19-0. 76),family support( Yes/No,OR = 0. 50,95% CI: 0. 28-0. 91) were protective factors for depression. Conclusions The prevalence of depression in patients with diabetes in Urumqi city is high,and it is related to multiple factors. Early diagnosis and intervention on depression in diabetic patients are recommended to improve the quality of life of diabetic patients.
Objective To investigate the prevalence and predictors of depression among patients with diabetes mellitus in Wulumuqi,China. Methods A cross-sectional survey was conducted among patients diagnosed with diabetes in outpatient clinics and inpatients from December 1st,2016 to April 30th,2017 in Xinjiang Medical University the Fifth Affiliated Hospital. The depression status was screened using Zung's Self-Rating Depression Scale. Logistic regression model was used to analyze the predictors of depression among diabetic patients. Results The prevalence of depression was 20. 00% in 500 patients with diabetes mellitus. The results of logistic regression analysis showed that female( compared to male,OR = 2. 18,95% CI: 1. 49-3. 19) and Uyghur( compared to Han ethnic group,OR = 2. 56,95% CI: 1. 17-5. 57) divorced or widowed( compared to being married,OR = 1. 74,95% CI: 1. 04-3. 07) were independent risk factors of depression. Education level equal to or higher than college( compared to primary school and lower,OR = 0. 38,95% CI: 0. 19-0. 76),family support( Yes/No,OR = 0. 50,95% CI: 0. 28-0. 91) were protective factors for depression. Conclusions The prevalence of depression in patients with diabetes in Urumqi city is high,and it is related to multiple factors. Early diagnosis and intervention on depression in diabetic patients are recommended to improve the quality of life of diabetic patients.
引文
[1]Xu Y,Wang L,He J,et al.Prevalence and control of diabetes in Chinese adults[J].JAMA,2013,310(9):948-959.
[2]Semenkovich K,Brown ME,Svrakic DM,et al.Depression in type 2 diabetes mellitus:prevalence,impact,and treatment[J].Drugs,2015,75(6):577-587.
[3]Leung KK,Lue BH,Lee MB,et al.Screening of depression in patients with chronic medical diseases in a primary care setting[J].Fam Pract,1998,15(1):67-75.
[4]Nouwen A,Winkley K,Twisk J,et al.Type 2 diabetes mellitus as a risk factor for the onset of depression:a systematic review and meta-analysis[J].Diabetologia,2010,53(12):2480-2486.
[5]Gu L,Xie J,Long J,et al.Epidemiology of major depressive disorder in mainland China:a systematic review[J].PLo S One,2013,8(6):e65356.
[6]Anderson RJ,Freedland KE,Clouse RE,et al.The prevalence of comorbid depression in adults with diabetes:a meta-analysis[J].Diabetes Care,2001,24(6):1069-1078.
[7]谢坤,张晓庆.住院2型糖尿病合并抑郁症患者生命质量的相关性研究[J].中华疾病控制杂志,2014,18(6):515-517.
[8]宁锋,王玉美,孙晓晖,等.青岛成人抑郁症和2型糖尿病患病率双向关联研究[J].中华疾病控制杂志,2016,20(4):357-361
[9]涂勇,高燕,冯泰山.伊犁州住院糖尿病患者并发抑郁症的相关性及影响因素[J].新疆医学,2014,44(4):32-34.
[10]Altemus M,Sarvaiya N,Neill Epperson C.Sex differences in anxiety and depression clinical perspectives[J].Front Neuroendocrinol,2014,35(3):320-330.
[11]周连华,周湘兰,施晓红,等.2型糖尿病合并抑郁症分析[J].中国临床医学,2004,11(6):1127-1128.
[12]崔益庆,王红萍,王彬彬.2型糖尿病合并抑郁症的相关性分析[J].医学信息,2015,28(33):36.
[13]玄丽霞.人格特征及社会支持关系对2型糖尿病患者抑郁症状的影响[J].潍坊医学院学报,2015,37(2):150-152.
[14]张玉霞.糖尿病患者并发抑郁症的影响因素及护理对策[J].糖尿病新世界,2015,35(6):203.
[2]Semenkovich K,Brown ME,Svrakic DM,et al.Depression in type 2 diabetes mellitus:prevalence,impact,and treatment[J].Drugs,2015,75(6):577-587.
[3]Leung KK,Lue BH,Lee MB,et al.Screening of depression in patients with chronic medical diseases in a primary care setting[J].Fam Pract,1998,15(1):67-75.
[4]Nouwen A,Winkley K,Twisk J,et al.Type 2 diabetes mellitus as a risk factor for the onset of depression:a systematic review and meta-analysis[J].Diabetologia,2010,53(12):2480-2486.
[5]Gu L,Xie J,Long J,et al.Epidemiology of major depressive disorder in mainland China:a systematic review[J].PLo S One,2013,8(6):e65356.
[6]Anderson RJ,Freedland KE,Clouse RE,et al.The prevalence of comorbid depression in adults with diabetes:a meta-analysis[J].Diabetes Care,2001,24(6):1069-1078.
[7]谢坤,张晓庆.住院2型糖尿病合并抑郁症患者生命质量的相关性研究[J].中华疾病控制杂志,2014,18(6):515-517.
[8]宁锋,王玉美,孙晓晖,等.青岛成人抑郁症和2型糖尿病患病率双向关联研究[J].中华疾病控制杂志,2016,20(4):357-361
[9]涂勇,高燕,冯泰山.伊犁州住院糖尿病患者并发抑郁症的相关性及影响因素[J].新疆医学,2014,44(4):32-34.
[10]Altemus M,Sarvaiya N,Neill Epperson C.Sex differences in anxiety and depression clinical perspectives[J].Front Neuroendocrinol,2014,35(3):320-330.
[11]周连华,周湘兰,施晓红,等.2型糖尿病合并抑郁症分析[J].中国临床医学,2004,11(6):1127-1128.
[12]崔益庆,王红萍,王彬彬.2型糖尿病合并抑郁症的相关性分析[J].医学信息,2015,28(33):36.
[13]玄丽霞.人格特征及社会支持关系对2型糖尿病患者抑郁症状的影响[J].潍坊医学院学报,2015,37(2):150-152.
[14]张玉霞.糖尿病患者并发抑郁症的影响因素及护理对策[J].糖尿病新世界,2015,35(6):203.