急性胃十二指肠溃疡穿孔的危险因素分析
|
摘要
目的:探讨急性胃十二指肠溃疡穿孔的危险因素。方法:回顾性分析2013年1月-2015年12月笔者所在医院收治的285例急性胃十二指肠溃疡穿孔患者为观察组,选取笔者所在医院同期诊治的285例胃十二指肠溃疡患者为对照组。资料分析采用单因素及多因素Logistic分析。结果:急性胃十二指肠溃疡穿孔多发生于冬春季节,以十二指肠为多见。单因素分析显示,患者性别、年龄、身体质量指数(BMI)、职业、文化程度、服用NSAIDs药物是急性胃十二指肠溃疡穿孔的危险因素(P<0.05)。多因素分析显示,患者的年龄、BMI、职业、文化程度、服用NSAIDs药物是急性胃十二指肠溃疡穿孔的独立危险因素(P<0.05)。结论:对于男性、年龄≥60岁、长期服用NSAIDs药物、文化程度及BMI指数低,并且职业为农民或无业患者,冬春季节应格外注意病情的发作,警惕穿孔的发生。
Objective:To explore the risk factors of acute perforation of gastroduodenal ulcer.Method:285 cases of acute gastroduodenal ulcer perforation in our hospital from January 2013 to December 2015 were selected as observation group.285 patients with gastroduodenal ulcer were selected as control group.Data were analyzed by single factor and multifactor Logistic review.Result:Acute gastroduodenal ulcer perforation often occurs in winter and spring,with the duodenum as the most common.The single factor analysis showed that gender,age,body mass index(BMI),occupation,education level and NSAIDs might be risk factors for acute gastroduodenal ulcer perforation(P<0.05).Multi-factors analysis showed that age,BMI,occupation,education level and NSAIDs were independent risk factors for acute gastroduodenal ulcer perforation(P<0.05).Conclusion:For men,over 60 years of age,taking NSAIDs for a long time,with low education level and BMI index,and occupational status as peasants or unemployed patients,winter and spring season should pay special attention to the occurrence of gastroduodenal ulcer,be alert to the occurrence of perforation.
Objective:To explore the risk factors of acute perforation of gastroduodenal ulcer.Method:285 cases of acute gastroduodenal ulcer perforation in our hospital from January 2013 to December 2015 were selected as observation group.285 patients with gastroduodenal ulcer were selected as control group.Data were analyzed by single factor and multifactor Logistic review.Result:Acute gastroduodenal ulcer perforation often occurs in winter and spring,with the duodenum as the most common.The single factor analysis showed that gender,age,body mass index(BMI),occupation,education level and NSAIDs might be risk factors for acute gastroduodenal ulcer perforation(P<0.05).Multi-factors analysis showed that age,BMI,occupation,education level and NSAIDs were independent risk factors for acute gastroduodenal ulcer perforation(P<0.05).Conclusion:For men,over 60 years of age,taking NSAIDs for a long time,with low education level and BMI index,and occupational status as peasants or unemployed patients,winter and spring season should pay special attention to the occurrence of gastroduodenal ulcer,be alert to the occurrence of perforation.
引文
[1]吴在德,吴肇汉.外科学[M].第7版.北京:人民卫生出版社,2008:427-439.
[2]葛步军,黄琦,王静,等.腹腔镜与开腹上消化道溃疡穿孔修补术的随机对照研究[J].中华胃肠外科杂志,2017,20(3):300.
[3]袁耀宗.消化性溃疡病诊断与治疗规范[J].全科医学临床与教育,2014,12(3):243-246.
[4]郑辛甜,崔龙.急性胃十二指肠溃疡穿孔的保守治疗[J].中华急诊医学杂志,2018,27(1):107-108.
[5] Wysocki A,Kamiński W,KrzywońJ.Seasonal periodicity of perforated peptic ulcers[J].Przeglad Lekarski,1999,56(3):189-191.
[6]俞旭波.消化性溃疡急性穿孔的危险因素分析[J].实用临床医学,2013,14(5):21-23.
[7]吴育美,李继昌,马医安,等.幽门螺杆菌感染并发消化性溃疡的危险因素及预防对策分析[J].现代生物医学进展,2017,17(8):1502-1504,1508.
[8]叶平,邓世辉,陈彩霞,等.3 826例消化性溃疡胃镜及流行病学分析[J].现代医药卫生,2008,24(19):2881-2882.
[9] Morris C R,Harvey I M,Stebbings W S L,et al.Anti-inflammatory drugs,analgesics and the risk of perforated colonic diverticular disease.[J].British Journal of Surgery,2010,90(10):1267-1272.
[10]霍惠峰,葛军,杨伟刚,等.非类固醇抗炎药与消化道穿孔[J].上海医学,2004,27(6):406-408.
[11]宗晔,赵海英,王青釭,等.NSAIDs相关性消化性溃疡出血与非NSAIDs消化性溃疡出血的临床对照研究[J].临床和实验医学杂志,2012,11(11):828-829.
[2]葛步军,黄琦,王静,等.腹腔镜与开腹上消化道溃疡穿孔修补术的随机对照研究[J].中华胃肠外科杂志,2017,20(3):300.
[3]袁耀宗.消化性溃疡病诊断与治疗规范[J].全科医学临床与教育,2014,12(3):243-246.
[4]郑辛甜,崔龙.急性胃十二指肠溃疡穿孔的保守治疗[J].中华急诊医学杂志,2018,27(1):107-108.
[5] Wysocki A,Kamiński W,KrzywońJ.Seasonal periodicity of perforated peptic ulcers[J].Przeglad Lekarski,1999,56(3):189-191.
[6]俞旭波.消化性溃疡急性穿孔的危险因素分析[J].实用临床医学,2013,14(5):21-23.
[7]吴育美,李继昌,马医安,等.幽门螺杆菌感染并发消化性溃疡的危险因素及预防对策分析[J].现代生物医学进展,2017,17(8):1502-1504,1508.
[8]叶平,邓世辉,陈彩霞,等.3 826例消化性溃疡胃镜及流行病学分析[J].现代医药卫生,2008,24(19):2881-2882.
[9] Morris C R,Harvey I M,Stebbings W S L,et al.Anti-inflammatory drugs,analgesics and the risk of perforated colonic diverticular disease.[J].British Journal of Surgery,2010,90(10):1267-1272.
[10]霍惠峰,葛军,杨伟刚,等.非类固醇抗炎药与消化道穿孔[J].上海医学,2004,27(6):406-408.
[11]宗晔,赵海英,王青釭,等.NSAIDs相关性消化性溃疡出血与非NSAIDs消化性溃疡出血的临床对照研究[J].临床和实验医学杂志,2012,11(11):828-829.