白蒿的提取及其应用前景
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摘要
白蒿(Herba artimisiae sieversianae)提取物的主要成分为挥发油类、黄酮类、木脂素类、萜类等,研究表明其有杀菌、消炎、抗氧化、抗紫外线灼伤等功效,在很多领域都有较大的开发空间和应用价值。通过对白蒿的生长资源分布、活性成分提取方法、成分组成及功效、在日用品方面的应用前景进行了综述分析,为白蒿的深入研究、开发和利用提供参考。
The main components of Herba Artemisia sieversiana extractive include essential oils, flavonoids, lignans and triterpenes. Researches have shown that it has antimicrobial, anti-inflammatory, antioxidant and anti-ultraviolet efficacy, with a great development space and application value in many fields. The growth resource distribution, extraction method of active ingredient, components and efficacy, and the application prospect in commodity field of Herba Artimisiae sieversiana were reviewed and analyzed, in order to provide an reference evidence for the further research, development and utilization of Herba Artimisiae sieversianae.
The main components of Herba Artemisia sieversiana extractive include essential oils, flavonoids, lignans and triterpenes. Researches have shown that it has antimicrobial, anti-inflammatory, antioxidant and anti-ultraviolet efficacy, with a great development space and application value in many fields. The growth resource distribution, extraction method of active ingredient, components and efficacy, and the application prospect in commodity field of Herba Artimisiae sieversiana were reviewed and analyzed, in order to provide an reference evidence for the further research, development and utilization of Herba Artimisiae sieversianae.
引文
[1]王汉章,杨毅生,卢智玲,等.《神农本草经》白蒿的考证[J].中药材,2001,24(4):294-295.
[2]苏新专,MILLER L H,李剑.青蒿素的发现与诺贝尔生理学或医学奖[J].中国科学:生命科学,2015,45(11):1148-1152.
[3]李春娜,占颖,刘洋洋,等.艾蒿药理作用和开发利用研究进展[J].中华中医药杂志,2014(12):3889-3891.
[4]HASHEM M.Antifungal properties of crude extracts of five Egyptian medicinal plants against dermatophytes and emerging fungi[J].Mycopathologia,2011,172(1):37-46.
[5]MAREGESI S M,PIETERS L,NGASSAPA O D,et al.Screening of some Tanzanian medicinal plants from Bunda district for antibacterial,antifungal and antiviral activities[J].Journal of ethnopharmacology,2008,119(1):58-66.
[6]KIRMIZIBEKMEZ H,DEMIRCI B,YESILADA E,et al.Chemical composition and antimicrobial activity of the essential oils of Lavandula stoechas L.ssp.stoechas growing wild in Turkey[J].Natural Product Communications,2009,4(7):1001-1006.
[7]ABAD M J,BEDOYA L M,APAZA L,et al.The artemisia L.Genus:a review of bioactive essential oils[J].Molecules,2012,17(3):2542-2566.
[8]刘春秀.植物活性成分的提取技术研究进展[J].安徽农业科学,2011,39(3):1273-1274,1277.
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[10]吕敏兰.白蒿挥发油的提取及其生物活性研究[D].哈尔滨:哈尔滨工业大学,2016.
[11]闫克玉,贾玉红,闫洪洋.水蒸气蒸馏萃取法和同时蒸馏萃取法提取款冬花挥发油的比较[J].河南农业科学,2008,37(7):91-93.
[12]薛月芹,袁珂,朱美晓,等.不同方法提取-GC/MS法分析淡竹叶中的挥发油化学成分[J].药物分析杂志,2009(6):954-960.
[13]崔刚.分子蒸馏法分离提取大蒜精油[J].食品科学,2010,24:236-240.
[14]谢丽莎,龚志强,欧阳炜,等.超临界CO2萃取法与水蒸气蒸馏法提取香茅草挥发油化学成分比较[J].安徽农业科学,2012,40(20):10397-10398.
[15]刘永青,任琳,张子锋,等.响应曲面法优化超声波提取白蒿总黄酮研究[J].天津农业科学,2015,21(11):63-67.
[16]孙志恒,吕敏兰,张智嘉,等.白蒿挥发油成分的测定及其抗氧化活性分析[J].分析化学,2017,45(11):1655-1661.
[17]李海亮,陈海魁,徐福利,等.大籽蒿精油化学成分及其抗菌抗氧化活性[J].食品科学,2016(20):63-68.
[18]韩小冰,马玲,马伟,等.不同方法提取蒿属植物有效物质的抑菌活性研究[J].森林工程,2008(3):13-16.
[19]刘群,邓治邦,杨智蕴,等.大籽蒿挥发油化学成分的研究[J].东北师大学报(自然科学版),1991(2):63-66.
[20]SULEIMENOV E M,OZEK T,DEMIRCI F,et al.Component composition and antimicrobial activity of essential oil from Artemisia kasakorum[J].Chemistry of Natural Compounds,2008,44(2):263-265.
[21]TKACHEV AV,KOROLYUK EA,LETCHAMO W.Chemical screening of essential oil bearing flora of Siberia.VII.Composition of the essential oil of Kadenia dubia(Schkuhr)Lavrova et V.N.Tichom.from Altai Region[J].Journal of Essential Oil Research,2005,17(6):636-637.
[22]王金兰,赵岩磊,王丹,等.大籽蒿化学成分研究[J].中草药,2017(17):3486-3492.
[23]周金沙,朱良,李乐,等.褐苞蒿挥发油成分及其抗菌活性研究[J].食品与机械,2014(2):152-155,254.
[24]张琪,郭国宁,苗瑞东,等.大籽蒿化学成分分析及抗癌活性研究[J].兰州大学学报,2004(4):68-71.
[25]GREGER H.Sesamin-type Lignans as chemical markers within artemisia[J].Biochemical Systematics And Ecology,1981,9(2-3):165-169.
[26]TAN R X,TANG H Q,HU J,et al.Lignans and sesquiterpene lactones from Artemisia sieversiana and Inula racemosa[J].Phytochemistry,1998,49(1):157-161.
[27]BOHLMANN F,ANG W,TRINKS C,et al.Dimeric guaianolides from artemisia-sieversiana[J].Phytochemistry,1985,24(5):1009-1015.
[28]桑吉,土旦卓玛,徐福春.藏药大籽蒿化学成分的研究现状[J].西藏科技,2012(12):77-78.
[29]黄瑞,张建水,刘烽,等.红没药醇和异红没药醇的合成进展[J].上海应用技术学院学报(自然科学版),2012,12(2):141-146.
[30]孙延芳,梁宗锁,刘新桐,等.一种新型白蒿精油空气清新剂的研制[J].应用化工,2011,40(11):1861-1863.
[2]苏新专,MILLER L H,李剑.青蒿素的发现与诺贝尔生理学或医学奖[J].中国科学:生命科学,2015,45(11):1148-1152.
[3]李春娜,占颖,刘洋洋,等.艾蒿药理作用和开发利用研究进展[J].中华中医药杂志,2014(12):3889-3891.
[4]HASHEM M.Antifungal properties of crude extracts of five Egyptian medicinal plants against dermatophytes and emerging fungi[J].Mycopathologia,2011,172(1):37-46.
[5]MAREGESI S M,PIETERS L,NGASSAPA O D,et al.Screening of some Tanzanian medicinal plants from Bunda district for antibacterial,antifungal and antiviral activities[J].Journal of ethnopharmacology,2008,119(1):58-66.
[6]KIRMIZIBEKMEZ H,DEMIRCI B,YESILADA E,et al.Chemical composition and antimicrobial activity of the essential oils of Lavandula stoechas L.ssp.stoechas growing wild in Turkey[J].Natural Product Communications,2009,4(7):1001-1006.
[7]ABAD M J,BEDOYA L M,APAZA L,et al.The artemisia L.Genus:a review of bioactive essential oils[J].Molecules,2012,17(3):2542-2566.
[8]刘春秀.植物活性成分的提取技术研究进展[J].安徽农业科学,2011,39(3):1273-1274,1277.
[9]LUCCHESI M E,CHEMAT F,SMADJA J.Solvent-free microwave extraction of essential oil from aromatic herbs:comparison with conventional hydro-distillation[J].Journal of chromatography.A,2004,1043(2):323-327.
[10]吕敏兰.白蒿挥发油的提取及其生物活性研究[D].哈尔滨:哈尔滨工业大学,2016.
[11]闫克玉,贾玉红,闫洪洋.水蒸气蒸馏萃取法和同时蒸馏萃取法提取款冬花挥发油的比较[J].河南农业科学,2008,37(7):91-93.
[12]薛月芹,袁珂,朱美晓,等.不同方法提取-GC/MS法分析淡竹叶中的挥发油化学成分[J].药物分析杂志,2009(6):954-960.
[13]崔刚.分子蒸馏法分离提取大蒜精油[J].食品科学,2010,24:236-240.
[14]谢丽莎,龚志强,欧阳炜,等.超临界CO2萃取法与水蒸气蒸馏法提取香茅草挥发油化学成分比较[J].安徽农业科学,2012,40(20):10397-10398.
[15]刘永青,任琳,张子锋,等.响应曲面法优化超声波提取白蒿总黄酮研究[J].天津农业科学,2015,21(11):63-67.
[16]孙志恒,吕敏兰,张智嘉,等.白蒿挥发油成分的测定及其抗氧化活性分析[J].分析化学,2017,45(11):1655-1661.
[17]李海亮,陈海魁,徐福利,等.大籽蒿精油化学成分及其抗菌抗氧化活性[J].食品科学,2016(20):63-68.
[18]韩小冰,马玲,马伟,等.不同方法提取蒿属植物有效物质的抑菌活性研究[J].森林工程,2008(3):13-16.
[19]刘群,邓治邦,杨智蕴,等.大籽蒿挥发油化学成分的研究[J].东北师大学报(自然科学版),1991(2):63-66.
[20]SULEIMENOV E M,OZEK T,DEMIRCI F,et al.Component composition and antimicrobial activity of essential oil from Artemisia kasakorum[J].Chemistry of Natural Compounds,2008,44(2):263-265.
[21]TKACHEV AV,KOROLYUK EA,LETCHAMO W.Chemical screening of essential oil bearing flora of Siberia.VII.Composition of the essential oil of Kadenia dubia(Schkuhr)Lavrova et V.N.Tichom.from Altai Region[J].Journal of Essential Oil Research,2005,17(6):636-637.
[22]王金兰,赵岩磊,王丹,等.大籽蒿化学成分研究[J].中草药,2017(17):3486-3492.
[23]周金沙,朱良,李乐,等.褐苞蒿挥发油成分及其抗菌活性研究[J].食品与机械,2014(2):152-155,254.
[24]张琪,郭国宁,苗瑞东,等.大籽蒿化学成分分析及抗癌活性研究[J].兰州大学学报,2004(4):68-71.
[25]GREGER H.Sesamin-type Lignans as chemical markers within artemisia[J].Biochemical Systematics And Ecology,1981,9(2-3):165-169.
[26]TAN R X,TANG H Q,HU J,et al.Lignans and sesquiterpene lactones from Artemisia sieversiana and Inula racemosa[J].Phytochemistry,1998,49(1):157-161.
[27]BOHLMANN F,ANG W,TRINKS C,et al.Dimeric guaianolides from artemisia-sieversiana[J].Phytochemistry,1985,24(5):1009-1015.
[28]桑吉,土旦卓玛,徐福春.藏药大籽蒿化学成分的研究现状[J].西藏科技,2012(12):77-78.
[29]黄瑞,张建水,刘烽,等.红没药醇和异红没药醇的合成进展[J].上海应用技术学院学报(自然科学版),2012,12(2):141-146.
[30]孙延芳,梁宗锁,刘新桐,等.一种新型白蒿精油空气清新剂的研制[J].应用化工,2011,40(11):1861-1863.