异种脱细胞真皮基质预防腮腺术后味觉出汗综合征
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摘要
目的:探讨应用异种脱细胞真皮基质预防腮腺肿瘤术后味觉出汗综合征的临床效果,以指导临床。方法:回顾性分析漯河市中心医院32例腮腺浅叶良性肿瘤病例,按照患者选用的治疗方法分为对照组20例和实验组12例,采用主观症状评价和Minor试验评估2组患者术后味觉出汗综合征的发生情况。结果:32例腮腺浅叶良性肿瘤病例术后均进行12~18个月的随访。实验组1/12例(8.5%)、对照组13/20例(65.0%)出现味觉出汗综合征主观症状,差异有统计学意义(P<0.05)。Minor试验中,试验组0/12例(0%)、对照组16/20例(80.0%)出现Frey综合征客观症状,差异有统计学意义(P<0.05)。结论:异种脱细胞真皮基质植入可以有效地预防腮腺肿瘤术后味觉出汗综合征的发生,值得临床推广和应用。
Objective To elvaluate the efficiency of heterogeneous acellular dermal matrix in the prevention of the Frey's syndrome after parotidectomy and put it in the clinic. Methods By means of retrospective analysis,32 patients with benign parotid tumors were divided into two groups according to their accepted treatment: the control group(n=20) and the observation group(n=12). The questionnaire and minor starch-iodion test were done to elvaluate the incidence of the Frey's syndrome. Results All patients were followed up lasting 12 to 18 months. One of 12(8.5%)in experiment group,13 of 20(65.0%) in control group had subjective symptoms of Frey 's syndrome. There was significant difference between the two groups( P<0.05). By Minor's starch iodine test,0(0%) cases in experimental group and 16(80.0%) cases in contro1 group had objective symptoms. The difference between the two groups was significantly statistical(P<0.05). Conclusion Transplantation of heterogeneous acellular dermal matrix can efficiently prevent Frey's syndrome after parotidectomy.
Objective To elvaluate the efficiency of heterogeneous acellular dermal matrix in the prevention of the Frey's syndrome after parotidectomy and put it in the clinic. Methods By means of retrospective analysis,32 patients with benign parotid tumors were divided into two groups according to their accepted treatment: the control group(n=20) and the observation group(n=12). The questionnaire and minor starch-iodion test were done to elvaluate the incidence of the Frey's syndrome. Results All patients were followed up lasting 12 to 18 months. One of 12(8.5%)in experiment group,13 of 20(65.0%) in control group had subjective symptoms of Frey 's syndrome. There was significant difference between the two groups( P<0.05). By Minor's starch iodine test,0(0%) cases in experimental group and 16(80.0%) cases in contro1 group had objective symptoms. The difference between the two groups was significantly statistical(P<0.05). Conclusion Transplantation of heterogeneous acellular dermal matrix can efficiently prevent Frey's syndrome after parotidectomy.
引文
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[2]Green RJ,Endersby S,Allen J,et al.Role of medical thermography in treatment of Frey’s syndrome with botulinum toxin A[J].Br J Oral Maxillofac Surg,2014,52(1):90-92.
[3]Hays LL,Novack AJ,Worsham JC.The Frey syndrome:a simple effective treatment[J].Otolaryngol Head Neck Surg,1982,90(4):419-425.
[4]盛成,司马国旗,蒋志毅,等.保留腮腺咬肌筋膜在预防Frey综合征中的应用[J].中国耳鼻咽喉头颈外科,2013,20(9):497-498.
[5]王文锋,郑东昕,黄欣,等.腮腺咬肌筋膜在腮腺肿瘤切除术中的应用[J].口腔颌面外科杂志,2012,22(3):211-213.
[6]刘平,贾玉荣,张淑香.胸锁乳突肌瓣预防腮腺切除术后味觉出汗综合征效果的Meta分析[J].中国循证医学杂志,2012,12(11):1385-1390.
[7]Sharma R.Prevention of Frey syndrome with superficial temporal fascia interpositioning:a retrospective study[J].Int J Oral Maxillofac Surg,2014,43(4):413-417.
[8]曾宪涛,郭毅,夏凌云,等.脱细胞真皮基质预防Frey综合征的系统评价[J].中国循证医学杂志,2011,11(1):76-83.
[9]叶文成,李莹,张波.应用异种脱细胞真皮基质预防腮腺术后味觉出汗综合征[J].中国口腔颌面外科杂志,2013,11(4):345-348.
[10]辛江波,蔡现良.腮腺咬肌筋膜联合异种脱细胞真皮基质预防味觉出汗综合征的作用研究[J].中国美容医学,2012,21(17):2204-2206.
[2]Green RJ,Endersby S,Allen J,et al.Role of medical thermography in treatment of Frey’s syndrome with botulinum toxin A[J].Br J Oral Maxillofac Surg,2014,52(1):90-92.
[3]Hays LL,Novack AJ,Worsham JC.The Frey syndrome:a simple effective treatment[J].Otolaryngol Head Neck Surg,1982,90(4):419-425.
[4]盛成,司马国旗,蒋志毅,等.保留腮腺咬肌筋膜在预防Frey综合征中的应用[J].中国耳鼻咽喉头颈外科,2013,20(9):497-498.
[5]王文锋,郑东昕,黄欣,等.腮腺咬肌筋膜在腮腺肿瘤切除术中的应用[J].口腔颌面外科杂志,2012,22(3):211-213.
[6]刘平,贾玉荣,张淑香.胸锁乳突肌瓣预防腮腺切除术后味觉出汗综合征效果的Meta分析[J].中国循证医学杂志,2012,12(11):1385-1390.
[7]Sharma R.Prevention of Frey syndrome with superficial temporal fascia interpositioning:a retrospective study[J].Int J Oral Maxillofac Surg,2014,43(4):413-417.
[8]曾宪涛,郭毅,夏凌云,等.脱细胞真皮基质预防Frey综合征的系统评价[J].中国循证医学杂志,2011,11(1):76-83.
[9]叶文成,李莹,张波.应用异种脱细胞真皮基质预防腮腺术后味觉出汗综合征[J].中国口腔颌面外科杂志,2013,11(4):345-348.
[10]辛江波,蔡现良.腮腺咬肌筋膜联合异种脱细胞真皮基质预防味觉出汗综合征的作用研究[J].中国美容医学,2012,21(17):2204-2206.