新疆一起家庭聚集性人间布鲁氏菌病暴发疫情调查
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摘要
目的掌握新疆某村人间布鲁氏菌病疫情发生原因、波及范围,查明传染源,采取有效的综合防治措施,及时控制当地布鲁氏菌病疫情蔓延。方法按照病例定义开展病例搜索,采用现场流行病学调查方法,调查每例病例,同时检测畜间布鲁氏菌病感染情况。结果该村共发现确诊病例10例和疑似病例2例,年龄中位数38岁(10～75岁);以低文化程度者为主、占83.3%,集中发生在第四村组A家庭;处理流产及流产物(OR=11.0, 95%CI为1.7～69.1)是本次暴发的危险因素;羊血清学阳性率为6.7%。结论该村发生的是一起由处理流产及流产物而引起的家庭聚集性人间布鲁氏菌病暴发事件;应加强布鲁氏菌病的联防联控工作,避免传染源继续驻留或转移其他地区而发生再次暴发或流行。
Objective To understand the cause and spreading area of human brucellosis in a village of Xinjiang, find out the source of infection, and take effective comprehensive prevention measures to control the spreading of brucellosis in time in local area. Methods The brucellosis cases were searched according to the definition of brucellosis and surveyed with the method of field epidemiological investigation. Meanwhile, the infection of brucellosis was detected in livestock. Results There were 10 confirmed and 2 suspected cases found in the village with median age of 38(10-75) years. The cases with loweducation background were the dominant and accounted for 83.3%. Most cases concentrated in family A of the 4 th group. The treatment of sheep abortion and abortion products were the risk factor(OR=11.0, 95%CI: 1.7-69.1) for this outbreak. The serological positive rate of sheep was 6.7%. Conclusions A family clustering outbreak of brucellosis occurred in a village due to the treatment of sheep abortion and abortion products. The coordinated prevention and control of brucellosis should be strengthened to avoid the outbreak or epidemic again due to the source of infection remaining in local area or spreading to other places.
Objective To understand the cause and spreading area of human brucellosis in a village of Xinjiang, find out the source of infection, and take effective comprehensive prevention measures to control the spreading of brucellosis in time in local area. Methods The brucellosis cases were searched according to the definition of brucellosis and surveyed with the method of field epidemiological investigation. Meanwhile, the infection of brucellosis was detected in livestock. Results There were 10 confirmed and 2 suspected cases found in the village with median age of 38(10-75) years. The cases with loweducation background were the dominant and accounted for 83.3%. Most cases concentrated in family A of the 4 th group. The treatment of sheep abortion and abortion products were the risk factor(OR=11.0, 95%CI: 1.7-69.1) for this outbreak. The serological positive rate of sheep was 6.7%. Conclusions A family clustering outbreak of brucellosis occurred in a village due to the treatment of sheep abortion and abortion products. The coordinated prevention and control of brucellosis should be strengthened to avoid the outbreak or epidemic again due to the source of infection remaining in local area or spreading to other places.
引文
[1]中华人民共和国卫生部.布鲁氏菌病诊断标准:WS 269-2007[S].北京:人民卫生出版社, 2007.
[2]中华人民共和国国家质量监督检验检疫总局.动物布鲁氏菌病诊断技术:GB/T 18646-2002[S].北京:人民卫生出版社, 2002.
[3]肖东楼.布鲁氏菌病防治手册[M].北京:人民卫生出版社, 2008.
[4]郑强,关晓冬,曹岩,等.近十年新疆人间布鲁氏菌病时空分布分析[J].疾病预防控制通报, 2015, 30(3):9-12.
[5]马晓菁,库尔班·居麦,舒展,等. 2012—2014年新疆动物布鲁氏菌病流行病学调查与分析[J].中国畜牧与兽医,2016, 48(5):111-114.
[6]施玉静,赖秋兰,牟笛,等.我国南北方2015—2016年人间布鲁氏菌病流行特性分析[J].中华流行病学杂志,2017, 38(4):435-440.
[7]王涛,马卫平,李爱巧,等.新疆达坂城区家畜布鲁氏菌病免疫效果评估[J].中国动物检疫杂志, 2016, 33(4):6-9, 22.
[8]薛红.浅析山羊引种疫病防控注意问题及对策[J].上海畜牧兽医通讯, 2015(6):90, 92.
[2]中华人民共和国国家质量监督检验检疫总局.动物布鲁氏菌病诊断技术:GB/T 18646-2002[S].北京:人民卫生出版社, 2002.
[3]肖东楼.布鲁氏菌病防治手册[M].北京:人民卫生出版社, 2008.
[4]郑强,关晓冬,曹岩,等.近十年新疆人间布鲁氏菌病时空分布分析[J].疾病预防控制通报, 2015, 30(3):9-12.
[5]马晓菁,库尔班·居麦,舒展,等. 2012—2014年新疆动物布鲁氏菌病流行病学调查与分析[J].中国畜牧与兽医,2016, 48(5):111-114.
[6]施玉静,赖秋兰,牟笛,等.我国南北方2015—2016年人间布鲁氏菌病流行特性分析[J].中华流行病学杂志,2017, 38(4):435-440.
[7]王涛,马卫平,李爱巧,等.新疆达坂城区家畜布鲁氏菌病免疫效果评估[J].中国动物检疫杂志, 2016, 33(4):6-9, 22.
[8]薛红.浅析山羊引种疫病防控注意问题及对策[J].上海畜牧兽医通讯, 2015(6):90, 92.