痛风发病机制的中西医认识
摘要
痛风的发病可能与遗传、饮食和外界环境等因素有关,其具体发病机制尚不清楚。通过对痛风的研究进展进行综述,剖析其发病机制,以期有益于指导临床防治,延缓疾病进展。
引文
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[25]毕黎琦,李萍.痛风的概念及发病机制[J].中国社区医师,2002,18(7):12-13.
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[28]孔悦,张冰,刘小青,等.黄嘌呤氧化酶活性在高尿酸血症动物模型中的变化[J].北京中医药大学学报,2004,27(6):38-40.
[29]RAGAB G,ELSHAHALY M,BARDIN T.Gout:Anold disease in new perspective-A review[J].J AdvRes,2017,8(5):495-511.
[30]李丹,张剑勇.痛风现代流行病学及降尿酸药物研究进展[J].风湿病与关节炎,2016,5(4):73-76.
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[32]LIPKOWITZ MS,LEAL-PINTO E,COHEN BE,et al.Galectin 9 is the sugar-regulated urate transporter/channel UAT[J].Glycoconj J,2002,19(7-9):491-498.
[33]石白,殷海波,张锦花.痛风现代流行病学及其发病机制研究进展[J].风湿病与关节炎,2012,1(6):51-55.
[34]KEITEL W.The High Priest of gout-Sir Alfred BaringGarrod(1819-1907)[J].Zeitschrift Fur Rheumatologie,2009,68(10):851-856.
[35]蒋莉,邢艳,周京国.炎性体及其在痛风发病中的作用[J].免疫学杂志,2010,26(10):916-919.
[36]TSCHOPP J,SCHRODER K.NLRP3 inflammasomeactivation:the convergence of multiple signalling pathways on ROS production?[J].Nature Rev Immunol,2010,10(3):210-215.
[37]ROCK KL,KATAOKA H,LAI JJ.Uric acid as a danger signal in gout and its comorbidities[J].Nat RevRheumatol,2013,9(1):13-23.
[38]KINGSBURY SR,CONAGHAN PG,MCDERMOTTMF.The role of the NLRP3 inflammasome in gout[J].J Inflamm Res,2011,4(1):39.
[2]MERRIMAN TR.An update on the genetic architecture of hyperuricemia and gout[J].Arthritis ResTher,2015,17(1):98.
[3]中华医学会风湿病学分会.原发性痛风诊断和治疗指南[J].中华风湿病学杂志,2011,15(6):410-413.
[4]RODDY E,DOHERTY M.Epidemiology of gout[J].Arthritis Res Ther,2010,12(6):223.
[5]阎胜利.痛风的流行病学特点[J].山东医药,2010,50(43):107.
[6]李丹,张剑勇.痛风现代流行病学及降尿酸药物研究进展[J].风湿病与关节炎,2016,5(4):73-76.
[7]GRASSI D,FERRI L,DESIDERI G,et al.Chronic hyperuricemia,uric acid deposit and cardiovascular risk[J].Curr Pharm Des,2013,19(13):2432-2438.
[8]CHOI HK,Curhan G.Gout:epidemiology and lifestylechoices[J].Curr Opin Rheumatol,2005,17(3):341-345.
[9]王平.痹证辨治体会[J].四川中医,2005,23(11):22-23.
[10]樊蕾.化痰逐瘀法治疗慢性痛风的临床研究[D].北京:中国中医科学院,2012.
[11]陈国权.痛风每作历节治[J].环球中医药,2017,10(5):552-554.
[12]巢元方.诸病源候论[M].北京:中国医药科技出版社,2011:547.
[13]王焘.外台秘要集要[M].沈阳:辽宁科学技术出版社,2007:133.
[14]姜徳友,李斗.痛风病的中医研究进展[J].辽宁中医杂志,2013,40(10):1953-1954.
[15]朱震亨.格致余论[M].刘更生,点校.天津:天津科学技术出版社,2000:14.
[16]沈知行.施应潮运用丹溪痛风方治疗痛风经验[J].山东中医药大学学报,2012,36(3):215-216.
[17]闫军堂,王雪茜,刘敏,等.王庆国教授治疗痛风经验撷菁[J].中华中医药学刊,2012,30(4):774-776.
[18]王忆黎,严余明.痛风从毒论治的体会[J].中国医药学报,2002,17(6):364-365.
[19]高红勤,朱良春,朱婉华,等.朱良春治疗痛风经验应用体会[J].中国中医药信息杂志,2014,21(8):114-115.
[20]张侠福,何峰,顾冬梅,等.朱良春“益肾蠲痹法”治疗疑难风湿病验案二则[J].风湿病与关节炎,2013,2(11):46-48.
[21]顾军花,茅建春,苏励.陈湘君扶正法治疗痛风性关节炎经验撷菁[J].上海中医药杂志,2008,42(9):4-5.
[22]张春,唐怡,罗海鸥.陈德济教授治疗痛风经验[J].现代中西医结合杂志,2003,12(2):187.
[23]万春平,李兆福,徐翔峰,等.痛风性关节炎免疫学发病机制研究进展[C]//中华中医药学会第十六届全国风湿病学术大会论文集,2012:425-428.
[24]AKAHOSHI T.Pathological mechanisms of gouty arthritis[J].Nihon Rinsho,2008,66(4):705-710.
[25]毕黎琦,李萍.痛风的概念及发病机制[J].中国社区医师,2002,18(7):12-13.
[26]HOCHBERG MC,SILMAN AJ,SMOLEN JS,et al.Rheumatology[M].3rd ed.New York:Mosby,2003:467-468.
[27]梁晓萍,梁琼麟,胡坪,等.高尿酸血症与痛风研究进展[J].中国药理学通报,2008,24(10):1265-1268.
[28]孔悦,张冰,刘小青,等.黄嘌呤氧化酶活性在高尿酸血症动物模型中的变化[J].北京中医药大学学报,2004,27(6):38-40.
[29]RAGAB G,ELSHAHALY M,BARDIN T.Gout:Anold disease in new perspective-A review[J].J AdvRes,2017,8(5):495-511.
[30]李丹,张剑勇.痛风现代流行病学及降尿酸药物研究进展[J].风湿病与关节炎,2016,5(4):73-76.
[31]BOBULESCU IA,MOE OW.Renal transport of uricacid:evolving concepts and uncertainties[J].AdvChronic Kidney Dis,2012,19(6):358-371.
[32]LIPKOWITZ MS,LEAL-PINTO E,COHEN BE,et al.Galectin 9 is the sugar-regulated urate transporter/channel UAT[J].Glycoconj J,2002,19(7-9):491-498.
[33]石白,殷海波,张锦花.痛风现代流行病学及其发病机制研究进展[J].风湿病与关节炎,2012,1(6):51-55.
[34]KEITEL W.The High Priest of gout-Sir Alfred BaringGarrod(1819-1907)[J].Zeitschrift Fur Rheumatologie,2009,68(10):851-856.
[35]蒋莉,邢艳,周京国.炎性体及其在痛风发病中的作用[J].免疫学杂志,2010,26(10):916-919.
[36]TSCHOPP J,SCHRODER K.NLRP3 inflammasomeactivation:the convergence of multiple signalling pathways on ROS production?[J].Nature Rev Immunol,2010,10(3):210-215.
[37]ROCK KL,KATAOKA H,LAI JJ.Uric acid as a danger signal in gout and its comorbidities[J].Nat RevRheumatol,2013,9(1):13-23.
[38]KINGSBURY SR,CONAGHAN PG,MCDERMOTTMF.The role of the NLRP3 inflammasome in gout[J].J Inflamm Res,2011,4(1):39.