右美托咪定在羟基磷灰石义眼台置入术中的应用
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摘要
目的:探讨在右美托咪定镇静状态下行义眼台置入术的安全性及效果。方法:选取需进行义眼台置入术患者32例(32只眼),术前15min静脉滴注右美托咪定(1.0μg/kg),10~15min滴注完毕,按常规方法行义眼台置入术。术后所置入的羟基磷灰石义眼台用0.75%的罗哌卡因注射液10ml浸泡30min后再行置入。结果:患者术中镇静且有良好配合,术后疼痛、结膜水肿及恶心呕吐症状均较轻。结论:右美托咪定应用在羟基磷灰石义眼台置入术前,能有效减轻术中与术后疼痛及术后反应。
Objective To explore the safety and efficacy of dexmedetomidine in the sedation of the right eye implantation surgery. Methods After prosthesis implantation, thirty-two cases of patients(thirty-two eyes). Preoperative 15 min intravenous infusion of dexmedetomidine(1.0μg/kg),10-15 min infusion is completed. According to conventional methods of eye-line implantation surgery. After the implantation of hydroxyapatite,hydroxyapatite eye drops with 0.75% ropivacaine injection 10 ml soak 30 min before implantation. Results Patients intraoperatie sedation and have a good cooperate. Postoperative pain, conjunctival edema and nausea and vomiting were mild. Conclusion The application of dexmedetomidine in hydroxyapatite orbital implantation, Can effectively reduce postoperative pain and postoperative response.
Objective To explore the safety and efficacy of dexmedetomidine in the sedation of the right eye implantation surgery. Methods After prosthesis implantation, thirty-two cases of patients(thirty-two eyes). Preoperative 15 min intravenous infusion of dexmedetomidine(1.0μg/kg),10-15 min infusion is completed. According to conventional methods of eye-line implantation surgery. After the implantation of hydroxyapatite,hydroxyapatite eye drops with 0.75% ropivacaine injection 10 ml soak 30 min before implantation. Results Patients intraoperatie sedation and have a good cooperate. Postoperative pain, conjunctival edema and nausea and vomiting were mild. Conclusion The application of dexmedetomidine in hydroxyapatite orbital implantation, Can effectively reduce postoperative pain and postoperative response.
引文
[1]李泰平,唐安.右美托咪定用于眼部整形手术的临床观察[J].中国美容整形外科杂志,2016,27(5):304-306.
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[11]Lin H,Faraklas I,Sampson C,et al.Use of dexmedetomidine for sedation in critically ill mechanically ventilated pediatric burn patients[J].J Burn Care Res,2011,32(1):98-103.
[12]Hoy SM,Keating GM.Dexmedetomidine:a review of its use for sedation in mechanically ventilated patients in an intensive care setting and for procedural sedation[J].Drugs,2011,71(11):1481-1501.
[13]Ha SH,Park IH,Lee MH,et al.The Use of Dexmedetomidine for awake craniotomy[J].Korean J Anesthesiol,2011,61(4):346-347.
[14]Ter Bruggen FF,Eralp I,Lelivel L,et al.Dexmedetomidine as a sedative in the Awake implantation of a neuromodulative System[J].Pain Pract,2016,23(1):24-25.
[15]Gioia L,Prandi E,Codenotti M,et al.Peribulbar anesthesia with either 0.75%ropivacaine or a 2%lidocaine and 0.5%bupivacaine mixture for vitreoretinal surgery:a double-blinded study[J].Anesh Analg,1999,8(3):739-742.
[16]Moon ST,Kim DH,Jo JK,et al.Bladder reconstruction using boving pericaedium in a case of enterovesical fistula[J].Voream J Urol,2011,52(2):150-153.
[17]高晓磊,孟叶.不同浓度罗哌卡因浸润麻醉对大鼠切口愈合的影响[J].中华麻醉学杂志,2012,32(12):1453-1456.
[18]赵娟,顾恩华.眼心反射的再认识[J].中华实验眼科杂志,2011,29(7):669-672.
[19]储小英,夏一梦,张富军,等.局麻或辅助右美托咪定用于斜视矫正术的比较[J].中华眼外伤职业眼病,2013,35(7):500-502.
[20]徐广,张陆希,万文萃,等.球周麻醉应用罗哌卡因添加右美托咪定的效果[J].中华眼外伤职业眼病杂志,2016,38(8):606-609.
[2]刘绍云,杨军,任敏荣,等.眼内容剜除术61例Ⅰ期羟基磷灰石义眼座植入术分析[J].中国实用眼科杂志,2014,32(6):779-781.
[3]王超庆,李燕飞,程春秀,等.同种异体脱细胞真皮用于HA义眼台暴露修复观察[J].中国实用眼科杂志,2015,33(3):294-296.
[4]唐香,杨林红,皇甫昌涛,等.羟基磷灰石义眼座植入术后眼座暴露原因及处理[J].中国实用眼科杂志,2013,31(9):1178-1180.
[5]Asacaso FJ,Peligero J,Longas J,et al.Regional anesthesia of the eye,orbit,and periocular skin[J].Clin Dermatol,2015,33(2):227-233.
[6]Kara-Junior N,Espindola RF,Valverde Filho J,et al.Ocular risk management in patients undergoing general anesthesia:an analysis of39,431 surgeries[J].Clinics(Sao Paulo),2015,70(8):541-543.
[7]Zhang X,Bai X.New therapeutic uses for an alpha2 adrenergic receptor agohist-dexmedetomidine in pain management[J].Neurosci Lett,2014,56(1):7-12.
[8]Keating GM.Dexmedetomidine:a review of its use for sedation in the intensive care setting[J].Drugs,2015,75(10):1119-1130.
[9]Afonso J,Reis F Dexmedetomidine:Current Role in Anesthesia and Intensive care[J].Rev Bras Anestesiol,2012,62(1):118133.
[10]Kunisawa T,Hanada S,Kurosawa A,et al.Dexmedetomidine was safely used for sedation during spinal anesthesia in a very elderly patient[J].J anesth,2010,24(6):938-941.
[11]Lin H,Faraklas I,Sampson C,et al.Use of dexmedetomidine for sedation in critically ill mechanically ventilated pediatric burn patients[J].J Burn Care Res,2011,32(1):98-103.
[12]Hoy SM,Keating GM.Dexmedetomidine:a review of its use for sedation in mechanically ventilated patients in an intensive care setting and for procedural sedation[J].Drugs,2011,71(11):1481-1501.
[13]Ha SH,Park IH,Lee MH,et al.The Use of Dexmedetomidine for awake craniotomy[J].Korean J Anesthesiol,2011,61(4):346-347.
[14]Ter Bruggen FF,Eralp I,Lelivel L,et al.Dexmedetomidine as a sedative in the Awake implantation of a neuromodulative System[J].Pain Pract,2016,23(1):24-25.
[15]Gioia L,Prandi E,Codenotti M,et al.Peribulbar anesthesia with either 0.75%ropivacaine or a 2%lidocaine and 0.5%bupivacaine mixture for vitreoretinal surgery:a double-blinded study[J].Anesh Analg,1999,8(3):739-742.
[16]Moon ST,Kim DH,Jo JK,et al.Bladder reconstruction using boving pericaedium in a case of enterovesical fistula[J].Voream J Urol,2011,52(2):150-153.
[17]高晓磊,孟叶.不同浓度罗哌卡因浸润麻醉对大鼠切口愈合的影响[J].中华麻醉学杂志,2012,32(12):1453-1456.
[18]赵娟,顾恩华.眼心反射的再认识[J].中华实验眼科杂志,2011,29(7):669-672.
[19]储小英,夏一梦,张富军,等.局麻或辅助右美托咪定用于斜视矫正术的比较[J].中华眼外伤职业眼病,2013,35(7):500-502.
[20]徐广,张陆希,万文萃,等.球周麻醉应用罗哌卡因添加右美托咪定的效果[J].中华眼外伤职业眼病杂志,2016,38(8):606-609.