特布他林联合布地奈德治疗小儿变异性咳嗽疗效分析
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摘要
目的分析特布他林联合布地奈德治疗小儿变异性咳嗽疗效。方法方便选择该院自2015年1月—2018年3月诊治的86例变异性咳嗽患儿,其中对照组41例给予布地奈德吸入治疗,观察组45例给予特布他林联合布地奈德吸入治疗,对两组治疗效果进行比较。结果观察组治疗有效率为95.56%,明显高于对照组75.61%,相对比(χ~2=14.372 3,P<0.05)。两组咳嗽症状改善时间对比,差异有统计学意义(P<0.05),体现在观察组咳嗽减轻时间、消失时间均相对较短。结论特布他林联合布地奈德治疗小儿变异性咳嗽有较好的疗效,值得在临床借鉴。
Objective To analyze the efficacy of terbutaline combined with budesonide in the treatment of children with variant cough. Methods Eighty-six children with variability cough were convenient selected from January 2015 to March2018 in our hospital. Among them, 41 patients in the control group received budesonide inhalation, and 45 patients in the observation group received terbutaline combined with budesonide inhalation treatment, comparing the effects of the two groups of treatment. Results The effective rate of treatment in the observation group was 95.56%, which was significantly higher than that in the control group 75.61%,the difference was statistically significant(χ~2=14.372 3,P<0.05). There was a significant difference in the improvement time of cough symptoms between the two groups(P<0.05), which was reflected in the observation group's cough reduction time and disappearance time were relatively short. Conclusion Terbutaline combined with budesonide has a good curative effect on children with variability cough, which is worthy of reference in clinical practice.
Objective To analyze the efficacy of terbutaline combined with budesonide in the treatment of children with variant cough. Methods Eighty-six children with variability cough were convenient selected from January 2015 to March2018 in our hospital. Among them, 41 patients in the control group received budesonide inhalation, and 45 patients in the observation group received terbutaline combined with budesonide inhalation treatment, comparing the effects of the two groups of treatment. Results The effective rate of treatment in the observation group was 95.56%, which was significantly higher than that in the control group 75.61%,the difference was statistically significant(χ~2=14.372 3,P<0.05). There was a significant difference in the improvement time of cough symptoms between the two groups(P<0.05), which was reflected in the observation group's cough reduction time and disappearance time were relatively short. Conclusion Terbutaline combined with budesonide has a good curative effect on children with variability cough, which is worthy of reference in clinical practice.
引文
[1]何莉莉,郑金炉.布地奈德联合特布他林雾化吸入治疗小儿哮喘急性发作的临床疗效及安全性[J].临床合理用药杂志,2018,11(24):5-6,8.
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[10]王相海,唐共珂.咳嗽变异性哮喘经特布他林雾化剂联合布地奈德混悬液治疗的效果[J].中国卫生标准管理,20178(18):86-87.
[2]靳冬梅.布地奈德混悬液联合硫酸特布他林雾化液治疗小儿喘息性支气管炎的临床效果[J/OL].河南医学研究,2018(15):1-2
[3]Zhang Junfu,Wang Yuxin,Li Xiangzhi,et al.Clinical observation of budesonide combined with terbutaline and ipratropium bromide in the treatment of children with bronchiolitis[J].Henan Medical Research,2018,27(14):2594-2595.
[4]黄春昀,彭红,陈斌华.布地奈德与丙酸倍氯米松辅助特布他林雾化吸入治疗小儿哮喘急性发作的临床疗效观察[J]海峡药学,2018,30(7):160-161.
[5]木巴来克·吐尔汗.布地奈德混悬液联合硫酸特布他林雾化吸入治疗小儿中度哮喘的临床疗效观察[J].临床医药文献电子杂志,2018,5(38):132-133.
[6]姚华雨.布地奈德、阿奇霉素联合特布他林治疗小儿急性支气管炎对疗效、临床症状消失时间、住院时间及不良反应的影响[J].北方药学,2018,15(3):104.
[7]Xu Qinghui.Evaluation of clinical effects of budesonide,terbutaline and ipratropium bromide combined with nebulization in the treatment of children with pneumonia mycoplasma pneumonia[J].Guide of China Medicine,2018,16(6):123-124.
[8]张建丽.硫酸特布他林雾化液和布地奈德混悬液联合多索茶碱治疗变异性哮喘患儿的临床研究[J].中国临床药理学杂志,2017,33(22):2215-2218.
[9]刘云玲.布地奈德联合特布他林吸入治疗咳嗽变异性哮喘临床效果观察[J].中国继续医学教育,2015,7(32):163-164.
[10]王相海,唐共珂.咳嗽变异性哮喘经特布他林雾化剂联合布地奈德混悬液治疗的效果[J].中国卫生标准管理,20178(18):86-87.