观察活血定痛汤治疗心脉瘀阻型冠心病心绞痛的临床疗效
|
摘要
目的探讨分析活血定痛汤治疗心脉瘀阻型冠心病心绞痛的临床疗效。方法 86例心脉瘀阻型冠心病心绞痛患者作为研究对象,按照治疗方法的不同分为中药组以及西药组,每组43例。西药组给予常规西药治疗,中药组在西药组的基础上给予活血定痛汤治疗。实验结束后,对比分析两组患者的血脂水平以及血液流变学情况。结果中药组患者的低密度脂蛋白胆固醇(LDL-C)为(2.28±0.35)mmol/L,高密度脂蛋白胆固醇(HDL-C)为(1.34±0.41)mmol/L,甘油三酯(TG)为(1.27±0.31)mmol/L,总胆固醇(TC)为(4.05±1.04)mmol/L,均优于西药组的(4.32±0.94)、(1.12±0.33)、(2.64±0.37)、(5.74±1.52)mmol/L,差异均具有统计学意义(P<0.05)。中药组患者的红细胞压积为(0.08±0.03)V/V,纤维蛋白原为(4.02±0.45)g/L,200/s的全血粘度为(5.92±0.98)m Pa·s,5/s的全血粘度为(10.28±3.98)m Pa·s,血浆粘度为(3.38±0.16)m Pa·s,均优于西药组的(0.52±0.14)V/V、(4.58±0.62)g/L、(7.43±1.30)m Pa·s、(13.12±3.22)m Pa·s、(3.81±0.40)m Pa·s,差异均具有统计学意义(P<0.05)。结论活血定痛汤治疗心脉瘀阻型冠心病心绞痛疗效显著,安全性较高,可有效的改善患者的心脏功能,值得临床推广应用。
Objective To explore and analyze the clinical curative effect of Huoxue Dingtong decoction in the treatment of heart arteries and veins and blood stasis resistance type of coronary heart disease and angina pectoris. Methods A total of 86 heart arteries and veins and blood stasis resistance type of coronary heart disease and angina pectoris patients were divided by different treatment methods into Chinese medicine group and western medicine group, with 43 cases in each group. The western medicine group received conventional western medicine for treatment, and Chinese medicine group received Huoxue Dingtong decoction on the basis of the western medicine for treatment. After experiment, comparative analysis were made on blood lipid levels and hemorheology in two groups. Results The Chinese medicine group had low density lipoprotein cholesterin(LDL-C) as(2.28±0.35) mmol/L, high density lipoprotein cholesterol(HDL-C) as(1.34±0.41) mmol/L, triglyceride(TG) as(1.27±0.31) mmol/L, total cholesterol(TC) as(4.05±1.04) mmol/L, which were all better than(4.32±0.94),(1.12±0.33),(2.64±0.37) and(5.74±1.52) mmol/L in the western medicine group, and their difference had statistical significance(P<0.05). The Chinese medicine group had hematocrit as(0.08±0.03) V/V, fibrinogen as(4.02±0.45) g/L, whole blood viscosity at 200/s as(5.92±0.98) m Pa·s, whole blood viscosity at 5/s as(10.28±3.98) m Pa·s, plasma viscosity as(3.38±0.16) m Pa·s, which were all better than(0.52±0.14) V/V,(4.58±0.62) g/L,(7.43±1.30) m Pa·s,(13.12±3.22) m Pa·s and(3.81±0.40) m Pa·s in the western medicine group, and their difference had statistical significance(P<0.05). Conclusion Huoxue Dingtong decoction shows significant curative effect for the treatment of heart arteries and veins and blood stasis resistance type of coronary heart disease and angina pectoris with high security, and it also can effectively improve cardiac function of patients. So this method is worthy of clinical application.
Objective To explore and analyze the clinical curative effect of Huoxue Dingtong decoction in the treatment of heart arteries and veins and blood stasis resistance type of coronary heart disease and angina pectoris. Methods A total of 86 heart arteries and veins and blood stasis resistance type of coronary heart disease and angina pectoris patients were divided by different treatment methods into Chinese medicine group and western medicine group, with 43 cases in each group. The western medicine group received conventional western medicine for treatment, and Chinese medicine group received Huoxue Dingtong decoction on the basis of the western medicine for treatment. After experiment, comparative analysis were made on blood lipid levels and hemorheology in two groups. Results The Chinese medicine group had low density lipoprotein cholesterin(LDL-C) as(2.28±0.35) mmol/L, high density lipoprotein cholesterol(HDL-C) as(1.34±0.41) mmol/L, triglyceride(TG) as(1.27±0.31) mmol/L, total cholesterol(TC) as(4.05±1.04) mmol/L, which were all better than(4.32±0.94),(1.12±0.33),(2.64±0.37) and(5.74±1.52) mmol/L in the western medicine group, and their difference had statistical significance(P<0.05). The Chinese medicine group had hematocrit as(0.08±0.03) V/V, fibrinogen as(4.02±0.45) g/L, whole blood viscosity at 200/s as(5.92±0.98) m Pa·s, whole blood viscosity at 5/s as(10.28±3.98) m Pa·s, plasma viscosity as(3.38±0.16) m Pa·s, which were all better than(0.52±0.14) V/V,(4.58±0.62) g/L,(7.43±1.30) m Pa·s,(13.12±3.22) m Pa·s and(3.81±0.40) m Pa·s in the western medicine group, and their difference had statistical significance(P<0.05). Conclusion Huoxue Dingtong decoction shows significant curative effect for the treatment of heart arteries and veins and blood stasis resistance type of coronary heart disease and angina pectoris with high security, and it also can effectively improve cardiac function of patients. So this method is worthy of clinical application.
引文
[1]魏萍.活血定痛汤联合西药治疗心脉瘀阻型冠心病心绞痛的临床疗效分析.世界最新医学信息文摘(连续型电子期刊)2015(89):110.
[2]叶先龙.活血定痛汤联合西药治疗心脉瘀阻型冠心病心绞痛的临床效果及心功能分析.实用中西医结合临床,2016,16(8):14-16.
[3]尹新军.西药联合活血定痛汤治疗心脉瘀阻型冠心病心绞痛的疗效观察.中西医结合心血管病电子杂志,2015,3(21):15-16.
[4]苏继朝.观察活血定痛汤联合西药治疗心脉瘀阻型冠心病心绞痛的疗效.中西医结合心血管病电子杂志,2015,3(8):142-143.
[5]蒋贵平.活血定痛汤联合西药治疗心脉瘀阻型冠心病心绞痛40例.中国实验方剂学杂志,2012,18(19):275-277.
[6]邓椿桥,邓永文.活血定痛汤联合单硝酸异山梨酯等西药治疗心脉瘀阻型冠心病心绞痛70例疗效观察.中国医药指南2013(34):216-217.
[7]宋海燕.活血定痛汤联合常规西药治疗心脉瘀阻型冠心病心绞痛66例临床疗效观察.实用中西医结合临床,2015,15(10):43.
[8]沈江君,喻茂尧.活血定痛汤与西药用于心脉瘀阻型冠心病心绞痛患者治疗中的临床效果.医药卫生(文摘版),2016(9):00296.
[9]胡岸秀.活血定痛汤联合西药治疗心脉瘀阻型冠心病心绞痛今日健康,2014(12):156.
[10]程国斌.用活血定痛汤联合西药治疗心脉瘀阻型冠心病心绞痛的效果观察.当代医药论丛,2014(15):181.
[11]王晓嫒.活血定痛汤联合西药治疗心脉瘀阻型冠心病心绞痛临床研究.医学信息,2015(26):215-214.
[12]王威.活血定痛汤联合西药治疗心脉瘀阻型冠心病心绞痛的临床效果分析.中国农村卫生,2014(11):3.
[13]马友合,卢晨,陈少军,等.中西医结合治疗心脉瘀阻型不稳定型心绞痛68例临床观察.北京中医药,2007,26(6):334-336.
[14]王丽琛.活血定痛汤治疗不稳定性心绞痛临床研究.辽宁中医药大学,2011.
[15]毕立冬.中西医结合治疗心血瘀阻型冠心病心绞痛疗效分析.医疗装备,2015(16):79-80.
[16]李秋芳.中西医结合治疗心血瘀阻型冠心病心绞痛疗效观察.现代中西医结合杂志,2011,20(22):2776-2777.
[2]叶先龙.活血定痛汤联合西药治疗心脉瘀阻型冠心病心绞痛的临床效果及心功能分析.实用中西医结合临床,2016,16(8):14-16.
[3]尹新军.西药联合活血定痛汤治疗心脉瘀阻型冠心病心绞痛的疗效观察.中西医结合心血管病电子杂志,2015,3(21):15-16.
[4]苏继朝.观察活血定痛汤联合西药治疗心脉瘀阻型冠心病心绞痛的疗效.中西医结合心血管病电子杂志,2015,3(8):142-143.
[5]蒋贵平.活血定痛汤联合西药治疗心脉瘀阻型冠心病心绞痛40例.中国实验方剂学杂志,2012,18(19):275-277.
[6]邓椿桥,邓永文.活血定痛汤联合单硝酸异山梨酯等西药治疗心脉瘀阻型冠心病心绞痛70例疗效观察.中国医药指南2013(34):216-217.
[7]宋海燕.活血定痛汤联合常规西药治疗心脉瘀阻型冠心病心绞痛66例临床疗效观察.实用中西医结合临床,2015,15(10):43.
[8]沈江君,喻茂尧.活血定痛汤与西药用于心脉瘀阻型冠心病心绞痛患者治疗中的临床效果.医药卫生(文摘版),2016(9):00296.
[9]胡岸秀.活血定痛汤联合西药治疗心脉瘀阻型冠心病心绞痛今日健康,2014(12):156.
[10]程国斌.用活血定痛汤联合西药治疗心脉瘀阻型冠心病心绞痛的效果观察.当代医药论丛,2014(15):181.
[11]王晓嫒.活血定痛汤联合西药治疗心脉瘀阻型冠心病心绞痛临床研究.医学信息,2015(26):215-214.
[12]王威.活血定痛汤联合西药治疗心脉瘀阻型冠心病心绞痛的临床效果分析.中国农村卫生,2014(11):3.
[13]马友合,卢晨,陈少军,等.中西医结合治疗心脉瘀阻型不稳定型心绞痛68例临床观察.北京中医药,2007,26(6):334-336.
[14]王丽琛.活血定痛汤治疗不稳定性心绞痛临床研究.辽宁中医药大学,2011.
[15]毕立冬.中西医结合治疗心血瘀阻型冠心病心绞痛疗效分析.医疗装备,2015(16):79-80.
[16]李秋芳.中西医结合治疗心血瘀阻型冠心病心绞痛疗效观察.现代中西医结合杂志,2011,20(22):2776-2777.