结直肠癌术后辅助化疗联合培土抗癌方的临床研究
|
摘要
目的:观察中医"治未病"理论在结直肠癌术后辅助化疗中的作用,方用培土抗癌方。方法:将60例结直肠癌术后患者随机分为两组各30例,治疗组采用培土抗癌方联合化疗。对照组采用单纯化疗。每4周1个疗程,共3个疗程。治疗结束后观察两组患者近期客观疗效、临床症状改善情况及生存质量变化情况。结果:治疗组虽在近期疾病局部复发及远处转移方面无明显差异(P>0. 05),但在改善患者乏力及纳差临床症状、改善生活质量方面,治疗组与对照组相比差异均具有统计学意义(P<0. 05或P<0. 01)。结论:中医"治未病"理论对结直肠癌术后复发与转移的防治作用虽无明确数据及证据支持,但在改善患者乏力纳差临床症状及生活质量方面是不容置疑的,中医"治未病"理论在结直肠癌术后的治疗中正起着潜移默化的作用。
Objective: To observe the role of the theory of"prevention of disease"in traditional Chinese medicine in postoperative adjuvant chemotherapy for colorectal cancer,and to use Peitu Kangai Recipe against cancer. Methods: Sixty patients with colorectal cancer after operation were randomly divided into two groups with 30 cases each. The treatment group was treated with Peitu Kangai Recipe combined with chemotherapy. The controlled group used chemotherapy alone. A course of treatment every 4 weeks,a total of 3 courses. Observed the two groups of patients after the treatment of recent objective efficacy,clinical symptoms and quality of life changes. Results: Although there was no significant difference of the local recurrence and distant metastasis between the two groups,( P > 0. 05),the difference between the treatment group and the controlled group was statistically significant in improving the clinical symptoms of fatigue and anorexia,and improving the quality of life. The difference was significance( P < 0. 05 or P < 0. 01). Conclusion: Although the prevention and treatment of postoperative recurrence and metastasis of colorectal cancer is not supported by clear data and evidence,it is unquestionable to improve the clinical symptoms and quality of life of patients with fatigue and poor health. "Prevention of disease"theory is playing a subtle role in the treatment of postoperative colorectal cancer.
Objective: To observe the role of the theory of"prevention of disease"in traditional Chinese medicine in postoperative adjuvant chemotherapy for colorectal cancer,and to use Peitu Kangai Recipe against cancer. Methods: Sixty patients with colorectal cancer after operation were randomly divided into two groups with 30 cases each. The treatment group was treated with Peitu Kangai Recipe combined with chemotherapy. The controlled group used chemotherapy alone. A course of treatment every 4 weeks,a total of 3 courses. Observed the two groups of patients after the treatment of recent objective efficacy,clinical symptoms and quality of life changes. Results: Although there was no significant difference of the local recurrence and distant metastasis between the two groups,( P > 0. 05),the difference between the treatment group and the controlled group was statistically significant in improving the clinical symptoms of fatigue and anorexia,and improving the quality of life. The difference was significance( P < 0. 05 or P < 0. 01). Conclusion: Although the prevention and treatment of postoperative recurrence and metastasis of colorectal cancer is not supported by clear data and evidence,it is unquestionable to improve the clinical symptoms and quality of life of patients with fatigue and poor health. "Prevention of disease"theory is playing a subtle role in the treatment of postoperative colorectal cancer.
引文
[1]李进.肿瘤内科诊治策略[M].上海:上海科技出版社,2017:116
[2]石远凯,孙燕.临床肿瘤内科手册[M].北京:人民卫生出版社,2015:395
[3]吴一龙.中国临床肿瘤学手册[M].北京:人民卫生出版设,2013:1102
[4]孙燕,石远凯.临床肿瘤内科手册[M].北京:人民卫生出版设,2007:978
[5]黄永刚,李从进,胡文宽.浅谈中医治未病是新世纪的健康模式[J].中华现代中医学杂志,2008,4(1):32
[6]周宜强.抗癌中草药[M].北京:化学化工出版社,2008:20,28,109,144
[2]石远凯,孙燕.临床肿瘤内科手册[M].北京:人民卫生出版社,2015:395
[3]吴一龙.中国临床肿瘤学手册[M].北京:人民卫生出版设,2013:1102
[4]孙燕,石远凯.临床肿瘤内科手册[M].北京:人民卫生出版设,2007:978
[5]黄永刚,李从进,胡文宽.浅谈中医治未病是新世纪的健康模式[J].中华现代中医学杂志,2008,4(1):32
[6]周宜强.抗癌中草药[M].北京:化学化工出版社,2008:20,28,109,144