眼底激光治疗糖尿病视网膜病变的临床研究
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摘要
目的探讨眼底激光治疗糖尿病视网膜病变(DR)的临床效果与价值。方法对本院2016年1月至2018年1月收治的DR患者90例进行回顾性分析,对照组行常规治疗,实验组在常规治疗的基础上行眼底激光治疗,观察其治疗前后的临床疗效。结果实验组临床疗效、视力评估(视力升高、视力下降)、临床症状改善时间等指标与对照组相比更优,有差异(P<0.05),其中两组患者视力稳定对比无差异(P> 0.05);90例患者治疗前后视力、眼底及荧光造影情况对比:依据治疗时间先后顺序来看,治疗60d后患者的视力、眼底与荧光造影明显优于治疗30d时和治疗前,各项临床症状均得到改善,且荧光造影结果显示呈阴性,证明视网膜病变好转明显。结论在DR临床治疗中,眼底激光治疗的临床效果极佳,有良好的临床应用价值。
Objective To investigate the clinical effect and value of fundus laser in the treatment of diabeticretinopathy(DR). Methods Ninety patients with DR admitted from January 2016 to January 2018 in our hospital wereretrospectively analyzed. The control group was treated with routine therapy, the experimental group was treated withfundus laser on the basis of routine treatment, and the clinical effect was observed before and after treatment. ResultsThe clinical efficacy, visual acuity evaluation(visual acuity increased, visual acuity decreased) and clinical symptomimprovement time in the experimental group were better than those in the control group(P<0.05), and there was nosignificant difference in the visual acuity between the two groups(P>0.05). Comparison of visual acuity, fundus andfluorescence contrast before and after treatment: according to the order of treatment time, the visual acuity, fundus andfluorescein of the patients after 60 days treatment were significantly better than those at 30 days after treatment andbefore treatment. All the clinical symptoms were improved, and the results of fluorescence angiography were negative,which proved that retinopathy was improved obviously. Conclusion In the clinical treatment of DR, the clinical effectof fundus laser treatment is excellent and has good clinical application value.
Objective To investigate the clinical effect and value of fundus laser in the treatment of diabeticretinopathy(DR). Methods Ninety patients with DR admitted from January 2016 to January 2018 in our hospital wereretrospectively analyzed. The control group was treated with routine therapy, the experimental group was treated withfundus laser on the basis of routine treatment, and the clinical effect was observed before and after treatment. ResultsThe clinical efficacy, visual acuity evaluation(visual acuity increased, visual acuity decreased) and clinical symptomimprovement time in the experimental group were better than those in the control group(P<0.05), and there was nosignificant difference in the visual acuity between the two groups(P>0.05). Comparison of visual acuity, fundus andfluorescence contrast before and after treatment: according to the order of treatment time, the visual acuity, fundus andfluorescein of the patients after 60 days treatment were significantly better than those at 30 days after treatment andbefore treatment. All the clinical symptoms were improved, and the results of fluorescence angiography were negative,which proved that retinopathy was improved obviously. Conclusion In the clinical treatment of DR, the clinical effectof fundus laser treatment is excellent and has good clinical application value.
引文
[1]司长峰,杨达珍,王佳,等.眼底激光治疗糖尿病视网膜病变的临床研究[J].临床眼科杂志,2016,24(5):407-409.
[2]朱振涛.眼底激光联合羟苯磺酸钙治疗糖尿病视网膜病变[J].国际眼科杂志,2017,17(2):288-290.
[3]Massin P,Marre M.Fundus photography for the screening for diabetic retinopathy[J].Diabetes&Metabolism,2002,28(2):151.
[4]杨晓海,李春暖.眼底激光联合雷珠单抗治疗糖尿病性视网膜病变的临床研究[J].医学信息,2016,29(12):285.
[5]刘晓琳,张贵森.眼底激光治疗糖尿病视网膜病变的临床效果观察[J].内蒙古医学杂志,2016,48(5):572-573.
[6]Listed N.Fundus photographic risk factors for progression of diabetic retinopathy.ETDRS report number 12.Early Treatment Diabetic Retinopathy Study Research Group[J].Ophthalmology,1991,98(5):823-833.
[7]吴伟柯.眼底激光联合雷珠单抗治疗糖尿病性视网膜病变的临床研究[J].糖尿病新世界,2017,20(20):182-183.
[8]李福琴,李秋明,谢春红.糖尿病视网膜病变激光光凝术的临床研究[J].中华眼外伤职业眼病杂志,2016,38(6):440-443.
[9]Moss SE,Klein R,Kessler SD,et al.Comparison between ophthalmoscopy and fundus photography in determining severity of diabetic retinopathy[J].Ophthalmology,1985,92(1):62-67.
[10]高波.糖尿病视网膜病变的眼底激光治疗效果评估[J].世界临床医学,2016,10(1):202.
[11]鹿麓.糖尿病视网膜病变行眼底激光光凝疗法128例临床研究[J].中国社区医师,2016,32(11):78.
[12]Williams GA,Scott IU,Haller JA,et al.Single-field fundus photography for diabetic retinopathy screening:a report by the American Academy of Ophthalmology[J].Ophthalmology,2004,111(5):1055-1062.
[13]胡军华,刘春兰,夏侯梨,等.眼底激光联合羟苯磺酸钙治疗糖尿病视网膜病变的效果观察[J].中国当代医药,2017,24(29):88-90.
[14]韩禹华.眼底激光联合雷珠单抗治疗糖尿病性视网膜病变的临床研究分析[J].中国医疗器械信息,2018,24(1):119-121.
[15]Vujosevic S,Benetti E,Massignan F,et al.Screening for diabetic retinopathy:1 and 3 nonmydriatic 45-degree digital fundus photographs vs 7 standard early treatment diabetic retinopathy study fields[J].American Journal of Ophthalmology,2009,148(1):111-118.
[16]李艳枝.眼底激光联合雷珠单抗治疗糖尿病性视网膜病变的临床研究[J].中国实用乡村医生杂志,2015,22(21):54-55.
[17]Aiello LP.Diabetic Retinopathy and Other Ocular Findings in the Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications Study[J].Diabetes Care,2014,37(1):8.
[18]王军.六锐胶囊联合视网膜激光光凝治疗糖尿病视网膜病变临床研究[J].亚太传统医药,2015,11(12):100-102.
[19]Grunwald JE,Brucker AJ,Grunwald E,et al.Retinal hemodynamics in proliferative diabetic retinopathy.A laser Doppler velocimetry study[J].Investigative Ophthalmology&Visual Science,1993,34(1):66-71.
[20]王卫平.眼底激光联合雷珠单抗治疗糖尿病性视网膜病变的临床研究[J].实用防盲技术,2017,12(4):151-153.
[2]朱振涛.眼底激光联合羟苯磺酸钙治疗糖尿病视网膜病变[J].国际眼科杂志,2017,17(2):288-290.
[3]Massin P,Marre M.Fundus photography for the screening for diabetic retinopathy[J].Diabetes&Metabolism,2002,28(2):151.
[4]杨晓海,李春暖.眼底激光联合雷珠单抗治疗糖尿病性视网膜病变的临床研究[J].医学信息,2016,29(12):285.
[5]刘晓琳,张贵森.眼底激光治疗糖尿病视网膜病变的临床效果观察[J].内蒙古医学杂志,2016,48(5):572-573.
[6]Listed N.Fundus photographic risk factors for progression of diabetic retinopathy.ETDRS report number 12.Early Treatment Diabetic Retinopathy Study Research Group[J].Ophthalmology,1991,98(5):823-833.
[7]吴伟柯.眼底激光联合雷珠单抗治疗糖尿病性视网膜病变的临床研究[J].糖尿病新世界,2017,20(20):182-183.
[8]李福琴,李秋明,谢春红.糖尿病视网膜病变激光光凝术的临床研究[J].中华眼外伤职业眼病杂志,2016,38(6):440-443.
[9]Moss SE,Klein R,Kessler SD,et al.Comparison between ophthalmoscopy and fundus photography in determining severity of diabetic retinopathy[J].Ophthalmology,1985,92(1):62-67.
[10]高波.糖尿病视网膜病变的眼底激光治疗效果评估[J].世界临床医学,2016,10(1):202.
[11]鹿麓.糖尿病视网膜病变行眼底激光光凝疗法128例临床研究[J].中国社区医师,2016,32(11):78.
[12]Williams GA,Scott IU,Haller JA,et al.Single-field fundus photography for diabetic retinopathy screening:a report by the American Academy of Ophthalmology[J].Ophthalmology,2004,111(5):1055-1062.
[13]胡军华,刘春兰,夏侯梨,等.眼底激光联合羟苯磺酸钙治疗糖尿病视网膜病变的效果观察[J].中国当代医药,2017,24(29):88-90.
[14]韩禹华.眼底激光联合雷珠单抗治疗糖尿病性视网膜病变的临床研究分析[J].中国医疗器械信息,2018,24(1):119-121.
[15]Vujosevic S,Benetti E,Massignan F,et al.Screening for diabetic retinopathy:1 and 3 nonmydriatic 45-degree digital fundus photographs vs 7 standard early treatment diabetic retinopathy study fields[J].American Journal of Ophthalmology,2009,148(1):111-118.
[16]李艳枝.眼底激光联合雷珠单抗治疗糖尿病性视网膜病变的临床研究[J].中国实用乡村医生杂志,2015,22(21):54-55.
[17]Aiello LP.Diabetic Retinopathy and Other Ocular Findings in the Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications Study[J].Diabetes Care,2014,37(1):8.
[18]王军.六锐胶囊联合视网膜激光光凝治疗糖尿病视网膜病变临床研究[J].亚太传统医药,2015,11(12):100-102.
[19]Grunwald JE,Brucker AJ,Grunwald E,et al.Retinal hemodynamics in proliferative diabetic retinopathy.A laser Doppler velocimetry study[J].Investigative Ophthalmology&Visual Science,1993,34(1):66-71.
[20]王卫平.眼底激光联合雷珠单抗治疗糖尿病性视网膜病变的临床研究[J].实用防盲技术,2017,12(4):151-153.