缺血性脑血管病介入治疗的临床观察
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摘要
目的:观察缺血性脑血管病介入治疗的临床治疗效果。方法:利用数字减影血管造影技术对150例缺血性脑血管病患者进行诊断,选择其中符合介入治疗条件的112例患者作为研究对象,并将所要研究的患者随机分成对照组和研究组,每组56例,对照组患者采用常规药物治疗,研究组在服用常规药物的基础上增加支架成形介入术治疗,比较两组临床治疗疗效。结果:治疗前,在神经功能缺损评分、病变血管改变方面两组对比无显著差异(P>0.05);治疗后,在神经功能缺损评分、病变血管改变方面,研究组显著低于对照组;在治疗总有效率方面,研究组显著高于对照组,组间对比差异明显,具有统计学意义(P<0.05)。结论:对缺血性脑血管病患者施行支架成形介入治疗方法能有效改善患者血管病变和神经功能,提高患者的治愈率。
Objective: To observe the clinical effect of interventional treatment of ischemic cerebrovascular disease.Methods: 150 patients with ischemic cerebrovascular disease were diagnosed by digital subtraction angiography.112 patients who met the interventional conditions were selected as the study subjects,and the patients to be studied were randomly divided into a control group and a study group,56 patients in each group.Control group was treated with conventional drugs,study group was treated with interventional stenting on the basis of conventional drugs,and clinical efficacy was compared between the two groups.Results: Before treatment,there was no significant difference between the two groups in terms of neurological deficit scores and changes in lesions(P>0.05).After treatment,the study group was significantly lower than the control group in terms of neurological deficit scores and lesional vascular changes.In terms of total treatment efficiency,the study group was significantly higher than the control group,and the difference between the groups was significant and statistically significant(P<0.05).Conclusion: The interventional treatment of stenting in patients with ischemic cerebrovascular disease can effectively improve the vascular lesions and neurological function,and improve the cure rate of patients.
Objective: To observe the clinical effect of interventional treatment of ischemic cerebrovascular disease.Methods: 150 patients with ischemic cerebrovascular disease were diagnosed by digital subtraction angiography.112 patients who met the interventional conditions were selected as the study subjects,and the patients to be studied were randomly divided into a control group and a study group,56 patients in each group.Control group was treated with conventional drugs,study group was treated with interventional stenting on the basis of conventional drugs,and clinical efficacy was compared between the two groups.Results: Before treatment,there was no significant difference between the two groups in terms of neurological deficit scores and changes in lesions(P>0.05).After treatment,the study group was significantly lower than the control group in terms of neurological deficit scores and lesional vascular changes.In terms of total treatment efficiency,the study group was significantly higher than the control group,and the difference between the groups was significant and statistically significant(P<0.05).Conclusion: The interventional treatment of stenting in patients with ischemic cerebrovascular disease can effectively improve the vascular lesions and neurological function,and improve the cure rate of patients.
引文
1 龙振钊,林耀波,陈汉威,等.缺血性脑血管病诊断和治疗的临床研究.中国医药指南,2013,11(14):423～424.
2 Fargen KM,Meyers PM,Khatri P,et al.Improvements in Recanaliza-tion with Modern Stroke Therapy:A Review of Prospective Ischemicstroke Trials During the Last Two Decades.Neurointerv Surg,2013,5(6):506～511.
3 周华东.缺血性脑血管病介入治疗进展.解放军医药杂志,2014,26(3):35～37.
4 陶庆铃,孙瑄,赵晖,等.颅内动脉狭窄的支架成形术与内科治疗的疗效观察.中华神经外科杂志,2012,21(4):233～235.
5 李军,张祥建.短暂性脑缺血发作与颅内、外动脉狭窄之间的关系探讨.脑与神经疾病杂志,2013,21(5):347～350.
6 刘亚红,徐格林,许亮,等.缺血性脑血管病血管内介入治疗并发症的预防.护理研究,2016,21(1A):63～64.
7 刘广青.56例缺血性脑血管病患者介入治疗的临床观察与护理.中国保健营养,2012,10:179.
8 张广平,刘楠,李慎茂.123例后循环缺血患者的脑血管造影分析.中国临床医生,2014,42(2):40～42.
9 朱利芳,缪建平.18例颈内动脉外伤性假性动脉瘤病人血管内介入治疗的临床观察.中华护理杂志,2015,42(9):758.
10 焦昌平,吴培,肖遥,等.支架成形术与药物治疗重度颅内动脉狭窄的长期疗效对比.中国脑血管病杂志,2013,10(12):630～634.
11 丁宇,陈贞芳,迟路湘,等.颈动脉狭窄血管内支架置入术后并发症的观察.第三军医大学学报,2015,25(24):2211～2215.
12 曲虹,周丽娟,梁国标.21例脑血管造影术及介入治疗的护理配合.中华护理杂志,2016,44(5):453～455.
13 陈自光,赵睿,童林艳,等.中西医联合康复治疗对急性期脑卒中并发抑郁患者的治疗效果研究.国际精神病学,2015,42(1):43～46.
14 Kidwell CS,Jahan R,Gornbein J,et al.A Trial of Imaging Selectionand Endovascular Treatment for Ischemic Stroke.N Engl J Med,2013,368(10):914～923.
15 王萍,王淑元.颅内支架治疗缺血性脑血管病96例的观察.护理研究,2016,24(1):67.
2 Fargen KM,Meyers PM,Khatri P,et al.Improvements in Recanaliza-tion with Modern Stroke Therapy:A Review of Prospective Ischemicstroke Trials During the Last Two Decades.Neurointerv Surg,2013,5(6):506～511.
3 周华东.缺血性脑血管病介入治疗进展.解放军医药杂志,2014,26(3):35～37.
4 陶庆铃,孙瑄,赵晖,等.颅内动脉狭窄的支架成形术与内科治疗的疗效观察.中华神经外科杂志,2012,21(4):233～235.
5 李军,张祥建.短暂性脑缺血发作与颅内、外动脉狭窄之间的关系探讨.脑与神经疾病杂志,2013,21(5):347～350.
6 刘亚红,徐格林,许亮,等.缺血性脑血管病血管内介入治疗并发症的预防.护理研究,2016,21(1A):63～64.
7 刘广青.56例缺血性脑血管病患者介入治疗的临床观察与护理.中国保健营养,2012,10:179.
8 张广平,刘楠,李慎茂.123例后循环缺血患者的脑血管造影分析.中国临床医生,2014,42(2):40～42.
9 朱利芳,缪建平.18例颈内动脉外伤性假性动脉瘤病人血管内介入治疗的临床观察.中华护理杂志,2015,42(9):758.
10 焦昌平,吴培,肖遥,等.支架成形术与药物治疗重度颅内动脉狭窄的长期疗效对比.中国脑血管病杂志,2013,10(12):630～634.
11 丁宇,陈贞芳,迟路湘,等.颈动脉狭窄血管内支架置入术后并发症的观察.第三军医大学学报,2015,25(24):2211～2215.
12 曲虹,周丽娟,梁国标.21例脑血管造影术及介入治疗的护理配合.中华护理杂志,2016,44(5):453～455.
13 陈自光,赵睿,童林艳,等.中西医联合康复治疗对急性期脑卒中并发抑郁患者的治疗效果研究.国际精神病学,2015,42(1):43～46.
14 Kidwell CS,Jahan R,Gornbein J,et al.A Trial of Imaging Selectionand Endovascular Treatment for Ischemic Stroke.N Engl J Med,2013,368(10):914～923.
15 王萍,王淑元.颅内支架治疗缺血性脑血管病96例的观察.护理研究,2016,24(1):67.