艾灸联合补阳还五汤 运动训练改善外周动脉疾病患者下肢运动功能的效果研究
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摘要
目的探讨艾灸联合补阳还五汤、运动训练改善外周动脉疾病患者下肢运动功能的效果。方法将60例轻中度外周动脉疾病患者随机分为对照组30例,采用常规治疗+运动训练;治疗组30例,在对照组常规治疗基础上结合艾灸+补阳还五汤治疗。分别于治疗前、治疗后观察2组患者踝肱指数(ABI)、经皮氧分压(TcPO_2)、血浆全血低切黏度(LWVP)、全血高切黏度(HWVP)、血浆比黏度(PV)、红细胞电泳时间(ET)、红细胞压积(HCT)、纤维蛋白原(Fb)、血小板聚集率(PAR)水平,6 min步行距离(6MWT),行走受损问卷(WIQ)中的行走距离、行走速度、爬梯能力评估结果。结果治疗后治疗组ABI与对照组比较差异无统计学意义(P>0.05);TcPO_2、6MWT及行走受损问卷中行走距离、行走速度、爬梯能力明显提高(P<0.05),且LWVP、HWVP、PV、ET、HCT、Fb和PAR水平改善均优于对照组(P<0.05)。结论艾灸联合补阳还五汤、运动训练治疗能明显改善外周动脉疾病患者下肢运动功能。
Objective To explore the clinical effect of moxibustion combined with Buyang Yang five Decoction and exercise training in the treatment of lower extremity motor function in patients with peripheral arterial disease.Methods 60 patients with mild and moderate peripheral artery disease were randomly divided into 30 cases in the control group and 30 cases in the treatment group,with routine therapy plus exercise training. On the basis of routine treatment in the control group,the treatment group was treated with Moxibustion plus Yang Yang five decoction. The ankle brachial index(ABI),transcutaneous oxygen partial pressure(Tc PO2),low cut whole blood viscosity of Plasma(LWVP),high Cut whole blood viscosity of Plasma(HWVP),plasma viscosity(PV),erythrocyte electrophoretic time(ET),hematocrit(HCT),fibrinogen(Fb),platelet aggregation ratio(PAR)and 6 minutes walk test(6 MWT)were measured before and after treatment,and the walking impairment questionnaire(WIQ)was used to evaluate the results.Results Compared with the control group and the same group before treatment,there was no statistical difference in ABI in the treatment group(P>0.05).Besides,Tc PO2,6 MWT,walking distanceof WIQ,walking speed of WIQ,ladder cl imbing ability of WIQ,LWVP,HWVP,PV,ET,HCT,Fb and PAR were better than that of the control group(P<0.05).Conclusion Moxibustion combined with Buyang Yang five Decoction and exercise training can obviously improve the lower extremity motor function of patients with peripheral artery disease.
Objective To explore the clinical effect of moxibustion combined with Buyang Yang five Decoction and exercise training in the treatment of lower extremity motor function in patients with peripheral arterial disease.Methods 60 patients with mild and moderate peripheral artery disease were randomly divided into 30 cases in the control group and 30 cases in the treatment group,with routine therapy plus exercise training. On the basis of routine treatment in the control group,the treatment group was treated with Moxibustion plus Yang Yang five decoction. The ankle brachial index(ABI),transcutaneous oxygen partial pressure(Tc PO2),low cut whole blood viscosity of Plasma(LWVP),high Cut whole blood viscosity of Plasma(HWVP),plasma viscosity(PV),erythrocyte electrophoretic time(ET),hematocrit(HCT),fibrinogen(Fb),platelet aggregation ratio(PAR)and 6 minutes walk test(6 MWT)were measured before and after treatment,and the walking impairment questionnaire(WIQ)was used to evaluate the results.Results Compared with the control group and the same group before treatment,there was no statistical difference in ABI in the treatment group(P>0.05).Besides,Tc PO2,6 MWT,walking distanceof WIQ,walking speed of WIQ,ladder cl imbing ability of WIQ,LWVP,HWVP,PV,ET,HCT,Fb and PAR were better than that of the control group(P<0.05).Conclusion Moxibustion combined with Buyang Yang five Decoction and exercise training can obviously improve the lower extremity motor function of patients with peripheral artery disease.
引文
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[2]谷涌泉.重视外周动脉疾病的研究[J].中国修复重建外科杂志,2010,24(9):1025-1026.
[3]MAYS R J,REGENSTEINER J G.Exercise therapy for claudication:latest advances[J].Curr Treat Options ardiovasc Med,2013,15(2):188-199.
[4]MCDERMOTT M M,ADES P,GURALNIK J M,et al.Treadmill exercise and resistance training in patients with peripheral arterial disease with and without intermittent claudication:a randomized controlled trial[J].JAMA,2009,301(1):165-174.