安宫牛黄丸在中风急性期的疗效分析
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摘要
目的探讨安宫牛黄丸在中风急性期疗效。方法抽选本院80例中风急性期患者作为研究对象,将其随机分为参照组与研究组,每组各40例。对照组开展常规治疗;研究组在开展常规治疗基础上,加上安宫牛黄丸治疗。结果研究组患者的治疗总有效率为97.5%,高于参照组的72.5%,组间比较,差异具有统计学意义(P <0.05)。治疗前,两组患者的神经功能缺损程度与日常生活能力指数评分比较,差异无统计学意义(P> 0.05);治疗后,研究组神经功能缺损程度与日常生活能力指数评分优于参照组,差异均具有统计学意义(P <0.05)。结论对中风急性期患者应用安宫牛黄丸治疗能减轻自由基对缺氧脑细胞的损害,促进脑脑细胞功能的恢复,并发症发生率大幅减少,并缩短住院时间,提高生活质量,获得患者与家属的认可与满意。
Objective To investigate the effect of Angong Niuhuang Pill on acute stroke. Methods 80 patients with acute stroke in our hospital were selected as the subjects of study. They were randomly divided into control group and research group, 40 cases in each group. The control group received routine treatment. On the basis of routine treatment, the study group was treated with angong niuhuang pill. Results The total effective rate was 97.5% in the study group, which was higher than 72.5% in the reference group. There was a significant difference between the two groups(P < 0.05). Before treatment, there was no significant difference in the degree of neurological impairment and the score of ADL index between the two groups(P > 0.05). After treatment, the neurological deficit degree and daily living ability index score of the study group were better than those of the reference group, and the difference was statistically significant(P <0.05). Conclusion Angong niuhuang pill can alleviate the damage of free radicals to hypoxic brain cells, promote the recovery of brain cell function,reduce the incidence of complications, shorten the hospital stay, improve the quality of life, and obtain the recognition and satisfaction of patients and their families.
Objective To investigate the effect of Angong Niuhuang Pill on acute stroke. Methods 80 patients with acute stroke in our hospital were selected as the subjects of study. They were randomly divided into control group and research group, 40 cases in each group. The control group received routine treatment. On the basis of routine treatment, the study group was treated with angong niuhuang pill. Results The total effective rate was 97.5% in the study group, which was higher than 72.5% in the reference group. There was a significant difference between the two groups(P < 0.05). Before treatment, there was no significant difference in the degree of neurological impairment and the score of ADL index between the two groups(P > 0.05). After treatment, the neurological deficit degree and daily living ability index score of the study group were better than those of the reference group, and the difference was statistically significant(P <0.05). Conclusion Angong niuhuang pill can alleviate the damage of free radicals to hypoxic brain cells, promote the recovery of brain cell function,reduce the incidence of complications, shorten the hospital stay, improve the quality of life, and obtain the recognition and satisfaction of patients and their families.
引文
[1]郗艳国,李双英,张赛.安宫牛黄丸联合鲜竹沥辅助治疗重型颅脑创伤临床研究[J].陕西中医,2017,38(2):163-164.
[2]邹振亮,陈志华,朱健明.安宫牛黄丸治疗缺血缺氧性脑病患者的临床效果[J].医疗装备,2018,31(13):98-99.
[3]陈新玉,钟飞雁,华县龙.安宫牛黄丸在ICU脑卒中患者的临床应用[J].深圳中西医结合杂志,2018,28(6):34-35.
[4]朱晓宇,郭胜亚,徐懿乔,等.安宫牛黄丸防治脑血管疾病作用研究[J].药物评价研究,2017,40(8):1067-1072.
[5]涂淮,彭皓均,赖纪才,等.安宫牛黄丸联合化学药治疗重型颅脑损伤及影响患者外周血Mg2+浓度的Meta分析[J].中国药房,2018,29(1):121-124.
[6]胡华白,马俊杰.安宫牛黄丸治疗急性脑血管病临床及药理机制研究进展[J].世界科学技术:中医药现代化,2015(7):1510-1513.
[7]于加军,邰阳升.安宫牛黄丸联合亚低温治疗脑出血并发中枢性高热的疗效观察[J].中医临床研究,2015,7(7):16-17.
[8]侯敏,王显凤,陈剑鸿.安宫牛黄丸辅助治疗缺血性中风急性期疗效的Meta分析[J].中国药房,2016,27(36):5104-5107.
[9]张伟骏,黄燕.安宫牛黄丸治疗急性脑中风的现状概述[J].中成药,2015,37(9):2019-2022.
[10]黄坡,郭玉红,赵京霞,等.安宫牛黄丸的临床研究进展[J].中国中医急症,2018,27(2):361-364.
[11]王欣美,张甦,王枚博,等.安宫牛黄丸体外安全性评价方法的研究[J].光谱学与光谱分析,2015,35(1):238-241.
[12]李志刚,卓友光,张国明,等.安宫牛黄丸加减治疗脑出血急性期脑损伤的临床疗效及对脑钠肽水平的影响[J].中国中医急症,2015,24(8):1448-1450.
[2]邹振亮,陈志华,朱健明.安宫牛黄丸治疗缺血缺氧性脑病患者的临床效果[J].医疗装备,2018,31(13):98-99.
[3]陈新玉,钟飞雁,华县龙.安宫牛黄丸在ICU脑卒中患者的临床应用[J].深圳中西医结合杂志,2018,28(6):34-35.
[4]朱晓宇,郭胜亚,徐懿乔,等.安宫牛黄丸防治脑血管疾病作用研究[J].药物评价研究,2017,40(8):1067-1072.
[5]涂淮,彭皓均,赖纪才,等.安宫牛黄丸联合化学药治疗重型颅脑损伤及影响患者外周血Mg2+浓度的Meta分析[J].中国药房,2018,29(1):121-124.
[6]胡华白,马俊杰.安宫牛黄丸治疗急性脑血管病临床及药理机制研究进展[J].世界科学技术:中医药现代化,2015(7):1510-1513.
[7]于加军,邰阳升.安宫牛黄丸联合亚低温治疗脑出血并发中枢性高热的疗效观察[J].中医临床研究,2015,7(7):16-17.
[8]侯敏,王显凤,陈剑鸿.安宫牛黄丸辅助治疗缺血性中风急性期疗效的Meta分析[J].中国药房,2016,27(36):5104-5107.
[9]张伟骏,黄燕.安宫牛黄丸治疗急性脑中风的现状概述[J].中成药,2015,37(9):2019-2022.
[10]黄坡,郭玉红,赵京霞,等.安宫牛黄丸的临床研究进展[J].中国中医急症,2018,27(2):361-364.
[11]王欣美,张甦,王枚博,等.安宫牛黄丸体外安全性评价方法的研究[J].光谱学与光谱分析,2015,35(1):238-241.
[12]李志刚,卓友光,张国明,等.安宫牛黄丸加减治疗脑出血急性期脑损伤的临床疗效及对脑钠肽水平的影响[J].中国中医急症,2015,24(8):1448-1450.