宜宾地区糖尿病女性患者伴性功能障碍的临床调查研究
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摘要
目的研究宜宾地区糖尿病女性患者伴性功能障碍的流行病学特点,为临床防治提供基础。方法选取2016年1月到2018年1月宜宾市第二人民医院诊治的60例糖尿病女性伴性功能障碍患者作为研究对象。将这60例患者作为观察组。另选取同期收治的单纯糖尿病女性患者40例作为对照组。采用调查问卷的形式,对比两组患者的年龄、糖尿病病史、空腹血糖水平、餐后血糖水平、糖化血红蛋白、糖尿病肾病、糖尿病神经病变及糖尿病视网膜病变情况,并采用Logistic回归分析糖尿病女性患者伴性功能障碍的危险因素。结果两组患者相比,观察组患者年龄(39.3±6.8)岁,糖尿病病史(11.3±6.8)年,空腹血糖水平(10.3±2.6)mmol/l,餐后血糖水平(14.7±1.9)mmol/l,糖化血红蛋白(9.3±2.3)mmol/l,12例糖尿病肾病,32例糖尿病神经病变,5例糖尿病视网膜病变,其中糖尿病病史、空腹血糖水平、餐后血糖水平、糖尿病神经病变均高于对照组,差异具有统计学意义(P<0.05)。Logistic回归分析显示,糖尿病病史、空腹血糖水平、餐后血糖水平、糖尿病神经病变均为糖尿病女性患者伴性功能障碍的独立危险因素。结论女性糖尿病患者并发性功能障碍的发病率较高,而其主要高危因素为糖尿病病史、空腹血糖水平、餐后血糖水平、糖尿病神经病变,这一研究结果值得临床借鉴。
Objective To study the epidemiological characteristics of women with diabetes complicated with sexual dysfunction in Yibing region, in order to provide basis for the clinical prevention and treatment.Methods The clinical data of 60 patients with diabetes complicated with sexual dysfunction in our hospital from January 2016 to January 2018 were selected as the observation group. In comparison, 40 patients treated with simple diabetes were selected as control group. The age, history of diabetes, fasting blood glucose level, postprandial blood glucose level, glycosylated hemoglobin, diabetic nephropathy and diabetic neuropathy and diabetic retinopathy were surveyed by questionare, and Logistic regression analysis was performed to analyze the risk factors. Results In the observation group, patients aged(39.3±6.8) years old, with a diabetes history of(11.3±6.8) years, fasting blood glucose levels of(10.3±2.6) mmol/l, postprandial blood glucose levels of(14.7±1.9) mmol/land glycosylated hemoglobin level of(9.3±2.3) mmol/l, including 12 cases of diabetic nephropathy, 32 cases of diabetic neuropathy and 5 cases of diabetic retinopathy. The history of diabetes, fasting blood glucose level, postprandial blood glucose levels and diabetic neuropathy levels in the observation group were higher than those in the control group, with statistically significant differnces(P<0.05). Logistic regression analysis showed that the history of diabetes, fasting blood glucose level, postprandial blood glucose level and diabetic neuropathy were all independent risk factors for women with diabetes combined with sexual dysfunction. Conclusions The incidence of diabetes complicated with sexual dysfunction is high and the main risk factors include history of diabetes, fasting blood glucose levels and postprandial blood glucose level and diabetic neuropathy, which is worthy of reference in clinical.
Objective To study the epidemiological characteristics of women with diabetes complicated with sexual dysfunction in Yibing region, in order to provide basis for the clinical prevention and treatment.Methods The clinical data of 60 patients with diabetes complicated with sexual dysfunction in our hospital from January 2016 to January 2018 were selected as the observation group. In comparison, 40 patients treated with simple diabetes were selected as control group. The age, history of diabetes, fasting blood glucose level, postprandial blood glucose level, glycosylated hemoglobin, diabetic nephropathy and diabetic neuropathy and diabetic retinopathy were surveyed by questionare, and Logistic regression analysis was performed to analyze the risk factors. Results In the observation group, patients aged(39.3±6.8) years old, with a diabetes history of(11.3±6.8) years, fasting blood glucose levels of(10.3±2.6) mmol/l, postprandial blood glucose levels of(14.7±1.9) mmol/land glycosylated hemoglobin level of(9.3±2.3) mmol/l, including 12 cases of diabetic nephropathy, 32 cases of diabetic neuropathy and 5 cases of diabetic retinopathy. The history of diabetes, fasting blood glucose level, postprandial blood glucose levels and diabetic neuropathy levels in the observation group were higher than those in the control group, with statistically significant differnces(P<0.05). Logistic regression analysis showed that the history of diabetes, fasting blood glucose level, postprandial blood glucose level and diabetic neuropathy were all independent risk factors for women with diabetes combined with sexual dysfunction. Conclusions The incidence of diabetes complicated with sexual dysfunction is high and the main risk factors include history of diabetes, fasting blood glucose levels and postprandial blood glucose level and diabetic neuropathy, which is worthy of reference in clinical.
引文
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[13] 胡明,余昆.美托洛尔与缬沙坦对男性高血压患者性功能影响的对比研究[J].中国性科学,2015,24(6):28-30.
[14] Chaudhary RK,Shamsi BH,Chen HM,et al,Risk factors for erectile dysfunction in patients with cardiovascular disease[J].J Int Med Res,2016,44(3):718-727.
[15] 张晶,何胜虎,李益民,等.男性高血压患者与其性功能、性激素相关性研究[J].实用临床医药杂志,2012,16(22):81-82.
[16] Djordjevic D,Vukovic I,Milenkovic PD,et al.Erectile dysfunction as a predictor of advanced vascular age[J].Andrology,2015,3(6):1125-1131.
[17] Mao QW,Li PG,Guo DZ,et al.Prostatic arterial embolization for the treatment of lower urinary tract symptoms due to large (>80 mL) benign prostatic hyperplasia:Result of midterm follow-up from Chinese population[J].BMC Urology,2015,15(1):33-40.
[18] 廖淑芳.25例女性糖尿病患者性功能障碍的护理干预[J].右江医学,2012,40(6):904-905.
[2] Skeldon SC,Detsky AS,Goldenberg SL,et al.Erectile dysfunction and undiagnosed diabetes,hypertension,and hypercholesterolemia[J].Ann Fam Med,2015,13(4):331-333.
[3] Viigimaa M,Vlachopoulos C,Lazaridis A,et al.Management of erectile dysfunction in hypertension:Tips and tricks[J].World J Cardiol,2014,6(9):908-915.
[4] Tektonidou MG,Dasgupta A,Ward MM.Risk of End-Stagerenal disease in patients with lupus nephritis,1971-2015:A systematic review and bayesian Meta-Analysis[J].Arthritis & Rheumatology,2016,68(6):1432-1441.
[5] Aragon E,Resontoc LP,Chan YH,et al.Long-term outcomes with multi-targeted immunosuppressive protocol in children with severe proliferative lupus nephritis[J].Lupus,2016,25(4):399-346.
[6] 丘勇超,杨槐,陈铭,等.性欲低下的中西医结合诊断与治疗[J].中国性科学,2012,21(7):3-8.
[7] Korbet SM,Whittier WL,Lewis EJ,et al.Theimpact of baseline serum creatinine on complete remission rate and Long-Term outcome in patients with severe lupus nephritis[J].Nephron Extra,2016,6(2):12-17.
[8] Fredy NRJ,María SHL,Alexandra BRS,et al.Clinical outcomes of kidney transplants on patients with end-stage renal disease secondary to lupus nephritis,polycystic kidney disease and diabetic nephropathy[J].Colombia Médica Cm,2016,47(1):51-58.
[9] Tesar V,Hruskova Z.Understandinghistolopathologic characteristics to predict Renal outcomes in lupus nephritis[J].Clinical Journal of the American Society of Nephrology,2017,12(5):711-715.
[10] Basu J,Sharma S.Erectile dysfunction heralds onset of cardiovascular disease[J].Practitioner,2016,260(1794):21-33.
[11] Spessoto LC,Facio FN,Arruda JG,et al.Association of hypertension with erectile function in chronic peripheral arterial insufficiency patients[J].J Clin Med Res,2016,8(8):582-584.
[12] 齐涛,张滨,金铭昱,等.男性自评性欲量表的编制[J].中国性科学,2011,20(12):8-12.
[13] 胡明,余昆.美托洛尔与缬沙坦对男性高血压患者性功能影响的对比研究[J].中国性科学,2015,24(6):28-30.
[14] Chaudhary RK,Shamsi BH,Chen HM,et al,Risk factors for erectile dysfunction in patients with cardiovascular disease[J].J Int Med Res,2016,44(3):718-727.
[15] 张晶,何胜虎,李益民,等.男性高血压患者与其性功能、性激素相关性研究[J].实用临床医药杂志,2012,16(22):81-82.
[16] Djordjevic D,Vukovic I,Milenkovic PD,et al.Erectile dysfunction as a predictor of advanced vascular age[J].Andrology,2015,3(6):1125-1131.
[17] Mao QW,Li PG,Guo DZ,et al.Prostatic arterial embolization for the treatment of lower urinary tract symptoms due to large (>80 mL) benign prostatic hyperplasia:Result of midterm follow-up from Chinese population[J].BMC Urology,2015,15(1):33-40.
[18] 廖淑芳.25例女性糖尿病患者性功能障碍的护理干预[J].右江医学,2012,40(6):904-905.