缩宫素联合卡前列素氨丁三醇预防产后出血的可行性分析
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摘要
目的分析缩宫素联合卡前列素氨丁三醇预防产后出血的可行性。方法选取2017年7月至2018年7月在本院分娩的52例产妇作为研究对象,采用信封式分组法将其分为对照组和观察组,各26例。对照组产妇采用缩宫素治疗,观察组产妇给予缩宫素+卡前列素氨丁三醇治疗。比较两组的治疗效果。结果观察组产妇的产时出血量及产后2、24 h出血量均少于对照组,子宫下降程度大于对照组,差异有统计学意义(P<0.05)。两组产妇的不良反应总发生率比较,差异无统计学意义(P>0.05)。观察组产后出血发生率为3.85%,显著低于对照组的26.92%,差异有统计学意义(P<0.05)。结论将缩宫素联合卡前列素氨丁三醇方案应用于产后出血预防中,效果显著,可以减少产妇的出血量降低产后出血率,对子宫恢复有促进作用,值得临床推广与应用。
Objective To analysis the feasibility of oxytocin and carboprost tromethamine in preventing postpartum hemorrhage. Methods Fifty-two parturients delivered in our hospital from July 2017 to July 2018 were selected as the study objects. The parturients were divided into control group and observation group by envelope grouping method, with 26 cases in each group. The control group was treated with oxytocin, while the observation group was treated with oxytocin and carboprost tromethamine. The therapeutic effects of the two groups were compared. Results The amount of intrapartum hemorrhage and 2, 24 hours hemorrhage after delivered in the observation group were less than those in the control group,and the degree of uterine decline was greater than that in the control group, and the differences were statistically significant(P<0.05). There was no significant difference in the total incidence of adverse reactions between the two groups(P>0.05). The incidence of postpartum hemorrhage in the observation group was 3.85%, which was significantly lower than26.92% in the control group, and the difference was statistically significant(P<0.05). Conclusion Oxytocin and carboprost tromethamine applied in the prevention of postpartum hemorrhage has a remarkable effect. It can reduce the amount of maternal hemorrhage, decrease the rate of postpartum hemorrhage and promote the recovery of uterus, which is worthy of clinical popularization and application.
Objective To analysis the feasibility of oxytocin and carboprost tromethamine in preventing postpartum hemorrhage. Methods Fifty-two parturients delivered in our hospital from July 2017 to July 2018 were selected as the study objects. The parturients were divided into control group and observation group by envelope grouping method, with 26 cases in each group. The control group was treated with oxytocin, while the observation group was treated with oxytocin and carboprost tromethamine. The therapeutic effects of the two groups were compared. Results The amount of intrapartum hemorrhage and 2, 24 hours hemorrhage after delivered in the observation group were less than those in the control group,and the degree of uterine decline was greater than that in the control group, and the differences were statistically significant(P<0.05). There was no significant difference in the total incidence of adverse reactions between the two groups(P>0.05). The incidence of postpartum hemorrhage in the observation group was 3.85%, which was significantly lower than26.92% in the control group, and the difference was statistically significant(P<0.05). Conclusion Oxytocin and carboprost tromethamine applied in the prevention of postpartum hemorrhage has a remarkable effect. It can reduce the amount of maternal hemorrhage, decrease the rate of postpartum hemorrhage and promote the recovery of uterus, which is worthy of clinical popularization and application.
引文
[1]于万芹.卡前列素氨丁三醇联合缩宫素在减少凶险性前置胎盘产后出血中的临床效果[J].河北医药,2017,39(12):1877-1879.
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[8]彭敏,孙国强,李敏,等.安列克与欣母沛治疗与预防产后出血的疗效比较[J].中国妇幼保健,2016,31(20):4128-4130.
[9]玉华,黄翎.益母草注射液联合缩宫素预防剖宫产术后再次妊娠阴道分娩产后出血的临床效果观察[J].广西医学,2017,39(5):719-720.
[10]黄益辉,李萍,曾玲.缩宫素、米索前列醇及卡前列素氨丁三醇联合应用预防性治疗产后出血疗效观察[J].内科,2019,14(2):174-176.
[2]刘会芹,赵运果,王芳,等.卡前列素氨丁三醇联合催产素预防高危产妇剖宫产术后出血效果及对血流动力学的影响[J].河北医药,2017,39(20):3085-3087.
[3]刘琦,方华英,符绿雨.安列克联合宫腔球囊填塞治疗前置胎盘剖宫产产后出血疗效观察[J].海南医学,2017,28(14):2373-2374.
[4]王翼飞,金玲玲,陈霞.产后即时使用安列克的临床效果观察[J].中国计划生育学杂志,2016,24(4):261-263.
[5]王慧玲,党慧娟,高娅,等.卡前列素氨丁三醇注射液在有出血高危因素的剖宫产术中的应用[J].中国性科学,2016,25(1):48-50.
[6]刘小媚,黄莉.催产素联合安列克预防剖宫产产后出血疗效分析[J].中国地方病防治杂志,2014,29(s1):182.
[7]卡提娅,李婷.氨甲环酸预防和治疗产后出血[J].现代妇产科进展,2017,26(9):713-715.
[8]彭敏,孙国强,李敏,等.安列克与欣母沛治疗与预防产后出血的疗效比较[J].中国妇幼保健,2016,31(20):4128-4130.
[9]玉华,黄翎.益母草注射液联合缩宫素预防剖宫产术后再次妊娠阴道分娩产后出血的临床效果观察[J].广西医学,2017,39(5):719-720.
[10]黄益辉,李萍,曾玲.缩宫素、米索前列醇及卡前列素氨丁三醇联合应用预防性治疗产后出血疗效观察[J].内科,2019,14(2):174-176.