高蛋白肠内营养液用于口腔颌面部恶性肿瘤术后效果观察
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摘要
目的:观察高蛋白肠内营养液对口腔颌面部恶性肿瘤患者术后营养状况的影响。方法:选取颌面部恶性肿瘤择期手术患者46例,随机分为实验组(23例),对照组(23例)。实验组给予高蛋白肠内营养液进行营养支持,对照组给予均衡肠内营养液,分别于术前1天、术后7天检测人体测量指标、营养指标、记录术后肠内营养液耐受情况及并发症的发生率。结果:实验组体重、TSF、ACM、体重丢失率下降小于对照组(P<0. 05);术后第7天实验组血清中的总白蛋白(TP)、白蛋白(ALB)、血红蛋白(Hb)与对照组比较无明显差异;实验组前清白蛋白(PA)、淋巴细胞总数(LY)、转铁蛋白(TF)显著高于对照组(P<0. 05);两组均能耐受肠内营养液,并发症无差异。结论:颌面部恶性肿瘤术后病人可耐受高蛋白肠内营养液,早期应用有效减轻体重下降,改善其营养状况。
Objective: To observe the effect of nutritional status on high-protein enteral nutrient solution in postoperative patients with oral and maxillofacial malignant tumors. Methods: 46 cases of patients with elective surgery for malignant tumors of maxillofacial region were selected and randomly divided into experimental group(23 cases) and control group(23 cases). The experimental group was given high-protein enteral nutrient solution for nutritional support, and the control group was given balanced enteral nutrient solution, which were tested respectively on human measurement indicators,nutrition indicators, and recorded the tolerance of postoperative enteral nutrient solution and the incidence of complications on the 1 th day before surgery and the 7 th days after surgery. Results: The weight, TSF, ACM and weight loss decreased less in the experimental group than in the control group(P<0.05). There was no significant difference in serum total albumin(TP), albumin(ALB) and hemoglobin(Hb) between the experimental group and the control group on the 7 th day after surgery.The serum albumin(PA), total lymphocyte(LY) and transferrin(TF) in the experimental group were significantly higher than those in the control group(P <0.05). Both groups were able to tolerate enteral nutrient solution, and there was no difference in complications. Conclusion: Postoperative patients with malignant maxillofacial tumors can tolerate high-protein enteral nutrient solution, and early application can effectively reduce weight loss and improve their nutritional status.
Objective: To observe the effect of nutritional status on high-protein enteral nutrient solution in postoperative patients with oral and maxillofacial malignant tumors. Methods: 46 cases of patients with elective surgery for malignant tumors of maxillofacial region were selected and randomly divided into experimental group(23 cases) and control group(23 cases). The experimental group was given high-protein enteral nutrient solution for nutritional support, and the control group was given balanced enteral nutrient solution, which were tested respectively on human measurement indicators,nutrition indicators, and recorded the tolerance of postoperative enteral nutrient solution and the incidence of complications on the 1 th day before surgery and the 7 th days after surgery. Results: The weight, TSF, ACM and weight loss decreased less in the experimental group than in the control group(P<0.05). There was no significant difference in serum total albumin(TP), albumin(ALB) and hemoglobin(Hb) between the experimental group and the control group on the 7 th day after surgery.The serum albumin(PA), total lymphocyte(LY) and transferrin(TF) in the experimental group were significantly higher than those in the control group(P <0.05). Both groups were able to tolerate enteral nutrient solution, and there was no difference in complications. Conclusion: Postoperative patients with malignant maxillofacial tumors can tolerate high-protein enteral nutrient solution, and early application can effectively reduce weight loss and improve their nutritional status.
引文
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[11]蒋奕,王惠临,刘剑仑.中性粒细胞/淋巴细胞比值评价肿瘤预后价值的研究进展[J].中国癌症防治杂志, 2016, 8(5):329
[2]王周涛,郑有华,何一青,等.广州地区3576例张口受限患者回顾性临床分析[J].口腔颌面修复学杂志, 2018, 19(3):146
[3]姚嘉晖,张美芳,张海峰,等.口腔颌面部肿瘤患者营养风险筛查和营养治疗[J].上海口腔医学, 2011, 20(1):105
[4]孙惠,方芳,吉凯.老年患者口腔颌面部肿瘤术后应激反应期的营养支持研究[J].中华老年口腔医学杂志, 2014, 12(1):25
[5]巫舢,丁元林,何玉清.糖脂代谢异常与肿瘤发生发展的相关性[J].中国肿瘤生物治疗杂志,2018, 25(9):955
[6]袁彬,睢岩,吕云,等.不同类型Ⅳ期恶性肿瘤住院患者的营养状况调查[J].现代肿瘤医学, 2018, 26(16):2619-2620
[7]葛奎,徐兵,张霖,等.经皮内镜下胃造口术改善口腔颌面部肿瘤综合治疗病人的营养状况[J].肠外与肠内营养,2013, 20(6):345
[8]李涛,吕家华,等.恶性肿瘤放射治疗患者肠内营养专家共识[J].肿瘤代谢与营养电子杂志, 2017, 4(3):276
[9]李增宁,陈伟,齐玉梅,等.恶性肿瘤患者膳食营养处方专家共识[J].肿瘤代谢与营养电子杂志, 2017, 4(4):400
[10]赵京阳,顾梅,朱长雨,等.全肠外营养在消化道恶性肿瘤术后患者中的应用分析[J].首都医科大学学报, 2014, 35(5):659
[11]蒋奕,王惠临,刘剑仑.中性粒细胞/淋巴细胞比值评价肿瘤预后价值的研究进展[J].中国癌症防治杂志, 2016, 8(5):329