改良锐性剥离对子宫内膜异位症患者的影响观察
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摘要
目的探究子宫内膜异位症患者应用改良锐性剥离术式和腔镜下常规钝性剔除对患者血清FSH、LH、E2的影响。方法本次实验对象全部选自2016年1月—2018年5月在本院进行治疗的72例子宫内膜异位症患者,按照入院先后顺序分成两组,即实验组(n=36)和对照组(n=36),对照组开展腔镜下常规钝性剔除,实验组开展改良锐性剥离术式,分析比较两种术式治疗成效。结果实验组在治疗后的巢皮质剥除厚度、剥除率、剥除病灶厚度、卵巢体积以及患侧卵巢AFC上,全部优于对照组,且对比差异有统计学意义(P <0.05)。且两组患者在E2、LH、FSH水平差异无统计学意义(P> 0.05)。结论子宫内膜异位症患者应用改良锐性剥离术式和腔镜下常规钝性剔除术后对患者的性激素水平影响较小,但是能够明显改善患者的卵巢体积、患侧卵巢AFC以及病灶剥除情况。
Objective To investigate the effect of modified sharp peeling and routine blunt rejection on serum FSH, LH and E_2 in patients with endometriosis. Methods All the subjects in this study were enrolled in 72 patients with endometriosis who were treated in our hospital from January 2016 to May 2018. They were divided into two groups according to the order of admission, the experimental group(n=36) and the control group(n=36). The control group underwent routine blunt culling under the laparoscopic technique, and the experimental group underwent modified sharp stripping procedure, and the effectiveness of the two surgical treatments were compared. Results In the experimental group, the thickness of the cortex peeling, the stripping rate, the thickness of the strip, the ovarian volume and the AFC of the affected side were all better than the control group, and the difference was statistically significant(P < 0.05).There were no significant differences in E_2, LH, and FSH levels between the two groups(P > 0.05). Conclusion Patients with endometriosis who have modified acute exfoliation and endoscopic blunt rejection have little effect on the patient's sex hormone levels, but can significantly improve the patient's ovarian volume, affected ovarian AFC and lesions.
Objective To investigate the effect of modified sharp peeling and routine blunt rejection on serum FSH, LH and E_2 in patients with endometriosis. Methods All the subjects in this study were enrolled in 72 patients with endometriosis who were treated in our hospital from January 2016 to May 2018. They were divided into two groups according to the order of admission, the experimental group(n=36) and the control group(n=36). The control group underwent routine blunt culling under the laparoscopic technique, and the experimental group underwent modified sharp stripping procedure, and the effectiveness of the two surgical treatments were compared. Results In the experimental group, the thickness of the cortex peeling, the stripping rate, the thickness of the strip, the ovarian volume and the AFC of the affected side were all better than the control group, and the difference was statistically significant(P < 0.05).There were no significant differences in E_2, LH, and FSH levels between the two groups(P > 0.05). Conclusion Patients with endometriosis who have modified acute exfoliation and endoscopic blunt rejection have little effect on the patient's sex hormone levels, but can significantly improve the patient's ovarian volume, affected ovarian AFC and lesions.
引文
[1]黄晓花,韩毓,韦佩佳,等.不同腹腔镜剥离术式对子宫内膜异位症患者性激素、窦卵泡数及卵巢体积的影响[J].中国内镜杂志,2017,23(5):74-78.
[2]陆海英.孕三烯酮治疗子宫内膜异位症对患者血清FSH、E2、LH及PROG的影响[J].河北医药,2016,38(7):1021-1023.
[3]田珲,孙杨.益肾消癥散结方对子宫内膜异位症术后患者E2、FSH、LH的影响[J].长春中医药大学学报,2016,32(3):581-583.
[4]刘秋颖,王亚萍,赵秋妍,等.腹腔镜卵巢子宫内膜异位囊肿剔除术及不同手术方式对卵泡丢失的影响[J].现代妇产科进展,2016,25(6):415-419.
[5]尹璐,刘平,王朝,等.米非司酮治疗子宫内膜异位症患者血清FSH、LH、E2水平及相关指标值变化研究[J].中国生育健康杂志,2017,28(3):277-279.
[6]印慧琴.腹腔镜下卵巢子宫内膜异位囊肿剥除术联合GnRH-a对子宫内膜异位囊肿患者FSH、LH、E2的影响[J].中国妇幼保健,2017,32(18):4589-4591.
[7]张燕,严婷,王彩波.腹腔镜卵巢子宫内膜异位症囊肿剥除术中不同止血方法对患者卵巢储备功能的影响[J].海南医学,2016,27(20):3353-3355.
[8]符婕,陈慧娟,栾莹,等.腹腔镜卵巢囊肿剔除术对女性卵巢储备功能的影响[J].医学临床研究,2017,34(5):875-878.
[9]张凤,赵绍杰,王金梅.子宫内膜异位症患者腹腔镜术后应用促性腺激素释放激素类似物的效果观察[J].实用临床医药杂志,2017,21(19):63-65.
[10]Wojciechowicz B,Kotwica G,Zglejc K,et al. Expression of 17β-hydroxysteroid dehydrogenase and the effects of LH,FSH and prolactin on oestrone and 17β-oestradiol secretion in the endometrium of pigs during early pregnancy and the oestrous cycle[J].Reprod Fertil Dev,2017,29(5):975-984.
[11]Kim YJ,Cha SW,Kim HO. Serum anti-Müllerian hormone levels decrease after endometriosis surgery[J]. Journal of Obstetrics and Gynaecology,2017,37(3):1-8.
[12]周勇,简玉辉,梁朝明,等.腹腔镜单侧卵巢子宫内膜异位囊肿剥除术对血清抗苗勒管激素水平变化的影响[J].现代妇产科进展,2016,25(2):120-122.
[2]陆海英.孕三烯酮治疗子宫内膜异位症对患者血清FSH、E2、LH及PROG的影响[J].河北医药,2016,38(7):1021-1023.
[3]田珲,孙杨.益肾消癥散结方对子宫内膜异位症术后患者E2、FSH、LH的影响[J].长春中医药大学学报,2016,32(3):581-583.
[4]刘秋颖,王亚萍,赵秋妍,等.腹腔镜卵巢子宫内膜异位囊肿剔除术及不同手术方式对卵泡丢失的影响[J].现代妇产科进展,2016,25(6):415-419.
[5]尹璐,刘平,王朝,等.米非司酮治疗子宫内膜异位症患者血清FSH、LH、E2水平及相关指标值变化研究[J].中国生育健康杂志,2017,28(3):277-279.
[6]印慧琴.腹腔镜下卵巢子宫内膜异位囊肿剥除术联合GnRH-a对子宫内膜异位囊肿患者FSH、LH、E2的影响[J].中国妇幼保健,2017,32(18):4589-4591.
[7]张燕,严婷,王彩波.腹腔镜卵巢子宫内膜异位症囊肿剥除术中不同止血方法对患者卵巢储备功能的影响[J].海南医学,2016,27(20):3353-3355.
[8]符婕,陈慧娟,栾莹,等.腹腔镜卵巢囊肿剔除术对女性卵巢储备功能的影响[J].医学临床研究,2017,34(5):875-878.
[9]张凤,赵绍杰,王金梅.子宫内膜异位症患者腹腔镜术后应用促性腺激素释放激素类似物的效果观察[J].实用临床医药杂志,2017,21(19):63-65.
[10]Wojciechowicz B,Kotwica G,Zglejc K,et al. Expression of 17β-hydroxysteroid dehydrogenase and the effects of LH,FSH and prolactin on oestrone and 17β-oestradiol secretion in the endometrium of pigs during early pregnancy and the oestrous cycle[J].Reprod Fertil Dev,2017,29(5):975-984.
[11]Kim YJ,Cha SW,Kim HO. Serum anti-Müllerian hormone levels decrease after endometriosis surgery[J]. Journal of Obstetrics and Gynaecology,2017,37(3):1-8.
[12]周勇,简玉辉,梁朝明,等.腹腔镜单侧卵巢子宫内膜异位囊肿剥除术对血清抗苗勒管激素水平变化的影响[J].现代妇产科进展,2016,25(2):120-122.