宣郁通经汤治疗子宫腺肌症痛经的效果
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摘要
目的探讨宣郁通经汤治疗子宫腺肌症痛经的效果。方法选取2016年1月～2018年1月我院门诊收治的88例子宫腺肌症伴痛经患者作为研究对象,根据随机数字表法将其分为参照组及实验组,每组各44例。参照组患者采用孕三烯酮口服治疗,实验组患者则给予宣郁通经汤灌肠治疗,两组均治疗3个月经周期。观察比较两组患者的临床疗效、痛经症状改善情况、疼痛程度评分变化以及不良反应发生情况。结果实验组和参照组的治疗总有效率分别为90.9%、88.6%,两组患者的治疗总有效率比较,差异无统计学意义(P>0.05)。治疗前,两组患者的痛经症状积分和视觉模拟(VAS)评分比较,差异无统计学意义(P>0.05);治疗后,两组患者的痛经症状积分和VAS评分均低于治疗前,差异有统计学意义(P<0.05),实验组患者的痛经症状积分和VAS评分均低于参照组,差异有统计学意义(P<0.05)。实验组患者的不良反应总发生率为4.5%,明显低于参照组的25.0%,差异有统计学意义(P<0.05)。结论宣郁通经汤治疗子宫腺肌症痛经能明显改善患者的痛经症状,减轻疼痛程度,且不良反应少,值得临床进行进一步研究应用。
Objective To explore the effect of Xuanyu Tongjing Decoction in the treatment of dysmenorrhea of uterine adenomyosis. Methods From January 2016 to January 2018, 88 cases of adenomyosis with dysmenorrhea were selected as the objects of research. According to the method of random number table, they were divided into the reference group and the experimental group, with 44 cases in each group. The clinical efficacy, dysmenorrhea symptoms, pain score and adverse reactions were observed and compared between the two groups. Results The total therapeutic efficiency of treatment in the experimental group and the reference group was 90.9% and 88.6%, respectively. There was no statistically significant difference in the total therapeutic efficiency between the two groups(P>0.05). Before treatment, the scores of dysmenorrhea symptom and visual analogue scale(VAS) were not significantly different between the two groups(P>0.05). After treatment, the scores of dysmenorrhea symptoms and VAS in both groups were lower than before treatment, and the differences were statistically significant(P<0.05). The scores of dysmenorrhea symptoms and VAS in the experimental group were lower than those in the control group, and the differences were statistically significant(P<0.05). The total incidence of adverse reactions in the experimental group was 4.5%, which was significantly lower than that in the control group(25.0%), and the difference was statistically significant(P<0.05). Conclusion Xuanyu Tongjing Decoction can obviously improve dysmenorrhea symptoms, relieve pain degree, and have fewer adverse reactions, which is worthy of further clinical study and application.
Objective To explore the effect of Xuanyu Tongjing Decoction in the treatment of dysmenorrhea of uterine adenomyosis. Methods From January 2016 to January 2018, 88 cases of adenomyosis with dysmenorrhea were selected as the objects of research. According to the method of random number table, they were divided into the reference group and the experimental group, with 44 cases in each group. The clinical efficacy, dysmenorrhea symptoms, pain score and adverse reactions were observed and compared between the two groups. Results The total therapeutic efficiency of treatment in the experimental group and the reference group was 90.9% and 88.6%, respectively. There was no statistically significant difference in the total therapeutic efficiency between the two groups(P>0.05). Before treatment, the scores of dysmenorrhea symptom and visual analogue scale(VAS) were not significantly different between the two groups(P>0.05). After treatment, the scores of dysmenorrhea symptoms and VAS in both groups were lower than before treatment, and the differences were statistically significant(P<0.05). The scores of dysmenorrhea symptoms and VAS in the experimental group were lower than those in the control group, and the differences were statistically significant(P<0.05). The total incidence of adverse reactions in the experimental group was 4.5%, which was significantly lower than that in the control group(25.0%), and the difference was statistically significant(P<0.05). Conclusion Xuanyu Tongjing Decoction can obviously improve dysmenorrhea symptoms, relieve pain degree, and have fewer adverse reactions, which is worthy of further clinical study and application.
引文
[1]魏玲,王军,张宗敏.宣郁通经汤与血府逐瘀胶囊治疗子宫内膜异位症痛经疗效观察[J].四川中医,2017,35(12):173-175.
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[10]李雪,蓝爱琴,李佩琼.子宫腺肌症患者血清MMP2/9的相关性及PVA联合重组人血管内皮抑素介入治疗的机制分析[J].海南医学院学报,2015,21(5):272-274.
[11]孙芯蕊.论宣郁通经汤加减治疗子宫内膜异位症痛经[J].内蒙古中医药,2017,36(13):8-9.
[12]王璐.督灸联合温经活血方治疗寒凝血瘀型子宫腺肌症痛经的临床观察[J].湖北中医杂志,2016,38(6):16-18.
[13]刘智衡.宣郁通经汤治疗痛经的疗效观察[J]实用中医药杂志,2016,32(11):1064-1065.
[14]张立新.中西医联合治疗子宫腺肌症痛经评价[J].光明中医,2017,32(11):1640-1641.
[15]曾艺文,刘耀岽.乌梅汤合宣郁通经汤加减治疗子宫腺肌症痛经的临床观察[J].中医药导报,2018,22(5):79-81.
[2]杨舫,时丽媛,王清.子宫腺肌症痛经患者生存质量及影响因素分析[J].中医杂志,2013,54(22):1929-1932.
[3]余燚薇,孙伟伟,赵瑞华.子宫腺肌症痛经的中医治疗方法研究进展[J].湖北中医杂志,2014,17(5):79-80.
[4]于绍卉,曲潇丽,王艳萍.宣郁通经汤加减配合针刺治疗经断前后诸证(肾虚肝郁型)的临床疗效分析[J].中外医疗,2017,26(31):169-170.
[5]孙惠君,胡奕芳,马琳.桂枝茯苓丸联合孕三烯酮对子宫腺肌症患者的治疗效果及疼痛缓解分析[J].当代医学,2017,23(10):65-67.
[6]龚红梅.比较米非司酮与孕三烯酮治疗子宫腺肌症的效果[J].中国处方药,2017,15(5):45-46.
[7]郭京华.芎归胶艾汤加减联合左炔诺孕酮治疗子宫腺肌症痛经临床研究[J].实用中医药杂志,2017,19(12):1395-1396.
[8]陈秀芳,何秀容,廖湘萍.柴苓消癥汤治疗子宫腺肌症痛经30例疗效观察[J].齐齐哈尔医学院学报,2016,37(22):2792-2794.
[9]陈滢,王晶,杨赛花.子宫腺肌症痛经发生因素临床分析[J].华南国防医学杂志,2012,26(1):23-25.
[10]李雪,蓝爱琴,李佩琼.子宫腺肌症患者血清MMP2/9的相关性及PVA联合重组人血管内皮抑素介入治疗的机制分析[J].海南医学院学报,2015,21(5):272-274.
[11]孙芯蕊.论宣郁通经汤加减治疗子宫内膜异位症痛经[J].内蒙古中医药,2017,36(13):8-9.
[12]王璐.督灸联合温经活血方治疗寒凝血瘀型子宫腺肌症痛经的临床观察[J].湖北中医杂志,2016,38(6):16-18.
[13]刘智衡.宣郁通经汤治疗痛经的疗效观察[J]实用中医药杂志,2016,32(11):1064-1065.
[14]张立新.中西医联合治疗子宫腺肌症痛经评价[J].光明中医,2017,32(11):1640-1641.
[15]曾艺文,刘耀岽.乌梅汤合宣郁通经汤加减治疗子宫腺肌症痛经的临床观察[J].中医药导报,2018,22(5):79-81.