丁苯酞软胶囊联合早期运动训练对急性脑梗死治疗效果及血清IL-10和TNF-α含量的影响
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摘要
目的:探讨在急性脑梗死的治疗上,早期运动训练、丁苯酞软胶囊联合应用的临床价值。方法:将我院收治的急性脑梗死患者(共82例)依照住院日期的单双号随机分成2组(例数相等),2组均接受常规治疗,与此同时,参照组接受早期运动训练,测验组在参照组的基础上另添用丁苯酞软胶囊,对2组患者的治疗成效予以评价。结果:测验组治疗后的肿瘤坏死因子-α(TNF-α)含量显著低于参照组,白介素-10(IL-10)含量显著高于参照组,差异具有统计学意义(P<0.05);测验组治疗后的Barthel指数显著高于参照组,NIHSS评分显著低于参照组,差异具有统计学意义(P<0.05)。结论:在急性脑梗死的治疗上,早期运动训练、丁苯酞软胶囊联合应用的效果突出。
Objective: To explore the clinical value of early exercise training and butyphthalide soft capsule in the treatment of acute cerebral infarction. Methods: Eighty-two patients with acute cerebral infarction were randomly divided into two groups according to the single and even number of patients in our hospital. The two groups received routine treatment, while the control group received early exercise training. In the test group, butyphthalide soft capsule was added to the reference group to evaluate the therapeutic effect of the two groups. Results: The content of TNF-α in the test group was significantly lower than that in the control group, and the content of IL-10 in the test group was significantly higher than that in the control group. The difference was statistically significant. The Barthel index of the test group was significantly higher than that of the control group, and the NIHSS score of the test group was significantly lower than that of the control group(P<0.05). Conclusion: In the treatment of acute cerebral infarction, the effect of early exercise training and butyphthalide soft capsule is obvious.
Objective: To explore the clinical value of early exercise training and butyphthalide soft capsule in the treatment of acute cerebral infarction. Methods: Eighty-two patients with acute cerebral infarction were randomly divided into two groups according to the single and even number of patients in our hospital. The two groups received routine treatment, while the control group received early exercise training. In the test group, butyphthalide soft capsule was added to the reference group to evaluate the therapeutic effect of the two groups. Results: The content of TNF-α in the test group was significantly lower than that in the control group, and the content of IL-10 in the test group was significantly higher than that in the control group. The difference was statistically significant. The Barthel index of the test group was significantly higher than that of the control group, and the NIHSS score of the test group was significantly lower than that of the control group(P<0.05). Conclusion: In the treatment of acute cerebral infarction, the effect of early exercise training and butyphthalide soft capsule is obvious.
引文
[1]左邦祺.低频电刺激结合早期康复训练治疗急性脑梗死的临床分析[J].当代医学,2018,24(9):43-45.
[2]袁井军,陈丽英.丁苯酞软胶囊对急性脑梗死患者的临床效果及血清C-反应蛋白的影响[J].医学理论与实践,2015,28(11):1408-1410.
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[4]赵巧娟.早期运动训练联合护理干预对急性脑梗死偏瘫患者肌力及神经功能的影响[J].河南医学研究,2017,26(15):2843-2844.
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[6]赵巧娟.早期运动训练联合护理干预对急性脑梗死偏瘫患者肌力及神经功能的影响[J].河南医学研究,2017,26(15):2843-2844.
[7]陈馨,刘新红.早期康复训练在急性脑梗死偏瘫患者护理中的应用[J].新疆医学,2017,47(9):1076-1078
[8]娄宇枫.早期康复锻炼对急性脑梗塞偏瘫患者肢体运动功能的影响评价[J].医学信息,2016,29(7):277-277.
[9]朱祖建.丁苯酞软胶囊联合早期运动训练对急性脑梗死治疗效果及血清IL-10和TNF-α含量的影响[J].福建医药杂志,2017,39(6):85-88.
[10]许向荣.早期康复训练对急性脑梗死患者肢体运动功能的影响[J].实用临床医药杂志,2016,20(14):14-16.
[11]尹楠,陈华,段瑞生.法舒地尔联合丁苯酞软胶囊治疗急性脑梗死的效果及对血清MMP-2、MMP-9水平的影响[J].河北医科大学学报,2018,39(12):1376-1379.
[12]牛慧艳,张占强,王海,等.丁苯酞软胶囊联合阿托伐他汀钙对急性脑梗死患者血清IL-6、IL-8和动脉粥样硬化斑块的影响[J].现代中西医结合杂志,2017,26(27):2968-2971.
[2]袁井军,陈丽英.丁苯酞软胶囊对急性脑梗死患者的临床效果及血清C-反应蛋白的影响[J].医学理论与实践,2015,28(11):1408-1410.
[3]姚涛,胡丹,湛彦强.依达拉奉联合丁苯酞软胶囊对早期急性脑梗死血清神经元特异性烯醇化酶、一氧化氮和超氧化物歧化酶水平的影响[J].神经损伤与功能重建,2017,12(2):111-113.
[4]赵巧娟.早期运动训练联合护理干预对急性脑梗死偏瘫患者肌力及神经功能的影响[J].河南医学研究,2017,26(15):2843-2844.
[5]梁权,樊启财,陈双杰.早期康复训练对急性脑梗死偏瘫患者运动功能和PCs、SDF-1α水平的影响[J].河北医药,2017,39(5):720-722.
[6]赵巧娟.早期运动训练联合护理干预对急性脑梗死偏瘫患者肌力及神经功能的影响[J].河南医学研究,2017,26(15):2843-2844.
[7]陈馨,刘新红.早期康复训练在急性脑梗死偏瘫患者护理中的应用[J].新疆医学,2017,47(9):1076-1078
[8]娄宇枫.早期康复锻炼对急性脑梗塞偏瘫患者肢体运动功能的影响评价[J].医学信息,2016,29(7):277-277.
[9]朱祖建.丁苯酞软胶囊联合早期运动训练对急性脑梗死治疗效果及血清IL-10和TNF-α含量的影响[J].福建医药杂志,2017,39(6):85-88.
[10]许向荣.早期康复训练对急性脑梗死患者肢体运动功能的影响[J].实用临床医药杂志,2016,20(14):14-16.
[11]尹楠,陈华,段瑞生.法舒地尔联合丁苯酞软胶囊治疗急性脑梗死的效果及对血清MMP-2、MMP-9水平的影响[J].河北医科大学学报,2018,39(12):1376-1379.
[12]牛慧艳,张占强,王海,等.丁苯酞软胶囊联合阿托伐他汀钙对急性脑梗死患者血清IL-6、IL-8和动脉粥样硬化斑块的影响[J].现代中西医结合杂志,2017,26(27):2968-2971.