对偏头痛患者睡眠质量和情绪障碍的研究
摘要
目的:了解偏头痛患者的睡眠质量和情绪障碍情况。方法:偏头痛患者50例为观察组,体检者50例为对照组,采用匹茨堡睡眠量表评分评价睡眠情况,汉密尔顿焦虑量表和汉密尔顿抑郁量表评估焦虑、抑郁状态。结果:观察组中34例(68.0%)失眠,对照组19例(38.0%)失眠,观察组睡眠障碍发生率高于对照组,差异有统计学意义(P<0.01)。观察组有40例(80.0%)存在情绪障碍,其中焦虑23例,抑郁17例,有12例为焦虑并抑郁,对照组有19例(38.0%)情绪障碍,其中焦虑10例,抑郁9例,3例为焦虑并抑郁,观察组情绪障碍发生率高于对照组,差异有统计学意义(P<0.01)。结论:偏头痛患者容易发生睡眠障碍和焦虑抑郁情绪。
引文
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[10]杨权.下丘脑-垂体-肾上腺皮质轴应激反应的中枢控制[J].生理科学进展, 2000, 31(3):222-226.
[11]Peroutka SJ. Neurogenic inflammation and migraine:implications for therapeutics[J]. Mol Interv. 2005,5(5):304-311.
[2]Goadsby PJ, Holland PR, Martins-Oliveira M. et al. Pathophysiology of migraine:a disorder of sensory processing[J]. Physiol Rev,2017, 97(2):553-622.
[3]Maizels M, Aurora S, Heinricher M.Beyond neurovascular:migraine as a dysfunctional neurolimbic pain network[J]. Headache,2012, 52(10):1553-1565.
[4]Andress-Rothrock D, King W, Rothrock J. An analysis of migraine triggers in a Clinic-Based population[J]. Headache, 2010,50(8):1366-1370.
[5]Zwart JA, Dyb G, Hagen K, et al. Depression and anxiety disorders associated with headache frequency. The Nord-Trondelag Health Study[J]. Eur J Neurol, 2003, 10(2):147-152.
[6]Cortelli P, Pierangeli G. Hypothalamus and headaches[J]. Neurol Sci, 2007, 28(Suppl 2):S198-S202.
[7]Kelman L, Rains JC. Headache and sleep:examination of sleep patterns and complaints in a large clinical sample of miaraineurs[J]. Headache, 2005, 45(7):904-910.
[8]Holland P, Goadsby PJ. The hypothalamic orexinergic system:Pain and primary headaches[J]. Headache, 2007, 47(6):951-962.
[9]Jo KB, Lee YJ, Lee IG, et al. Association of pain intensity,pain-related disability, and depression with hypothalamus-pituitary-adrenal axis function in female patients with chronic temporomandibular disorders[J]. Psychoneuroendocrinology,2016, 69:106-115.
[10]杨权.下丘脑-垂体-肾上腺皮质轴应激反应的中枢控制[J].生理科学进展, 2000, 31(3):222-226.
[11]Peroutka SJ. Neurogenic inflammation and migraine:implications for therapeutics[J]. Mol Interv. 2005,5(5):304-311.