摘要
冠状动脉慢性完全闭塞(Chronic Total Occlusion,CTO)病变指冠脉血管完全闭塞且闭塞时间大于3个月。CTO开通获益情况取决于靶血管支配的区域是否有存活心肌和存活心肌的面积。目前大的医疗中心评估存活心肌的方法有心脏磁共振成像(cardiacmagneticresonance,CMR)、正电子发射计算机断层扫描(PET)等,而相对小的基层医院则只有超声心动图(UCG)等评估方法。本文将对存活心肌的检测方法及各方法间的相关性作一综述。
引文
[1]Montalescot G,Sechtem U,Achenbach S,et al.2013 ESC guidelines on the management of stable coronary artery disease:the Task Force on the management of stable coronary artery disease of the European Society of Cardiology[J].Eur Heart J,2013,34(38):2949-3003.
[2]Stone GW,Kandzari DE,Mehran R,et al.Percutaneous recanalization of chronically occluded coronary arteries:a consensus document:part I[J].Circulation,2005,112(15):2364-2372.
[3]Yamamoto E,Natsuaki M,Morimoto T,et al.Long-term outcomes after percutaneous coronary intervention for chronic total occlusion(from the CREDO-Kyoto registry cohort-2)[J].Am J Cardiol,2013,112(6):767-774.
[4]Jeroudi OM,Alomar ME,Michael TT,et al.Prevalence and management of coronary chronic total occlusions in a tertiary Veterans Affairs hospital[J].Catheter Cardiovasc Interv,2014,84(4):637-643.
[5]Fefer P,Knudtson ML,Cheema AN,et al.Current perspectives on coronary chronic total occlusions:the Canadian Multicenter Chronic Total Occlusions Registry[J].J Am Coll Cardiol,2012,59(11):991-997.
[6]Retraction note:Meta-analysis of the effect of percutaneous coronary intervention on chronic total coronary occlusions[J].J Cardiothorac Surg,2015,10:43.
[7]AndréR,Dumonteil N,Lhermusier T,et al.In-hospital and long-term outcomes after percutaneous coronary intervention for chronic total occlusion in elderly patients:A consecutive,prospective,single-centre study[J].Arch Cardiovasc Dis,2016,109(1):13-21.
[8]Bucciarelli-Ducci C,Auger D,Di MC,et al.CMR Guidance for Recanalization of Coronary Chronic Total Occlusion[J].JACC Cardiovasc Imaging,2016,9(5):547-556.
[9]Baks T,van Geuns RJ,Duncker DJ,et al.Prediction of left ventricular function after drug-eluting stent implantation for chronic total coronary occlusions[J].J Am Coll Cardiol,2006,47(4):721-725.
[10]Beleslin B,Ostojic M,Djordjevic-Dikic A,et al.The value of fractional and coronary flow reserve in predicting myocardial recovery in patients with previous myocardial infarction[J].Eur Heart J,2008,29(21):2617-2624.
[11]Ferda J,Hromádka M,Baxa J.Imaging of the myocardium using(18)F-FDG-PET/MRI[J].Eur J Radiol,2016,85(10):1900-1908.
[12]Kloner RA,Przyklenk K,Patel B.Altered myocardial states.The stunned and hibernating myocardium[J].Am J Med,1989,86(1A):14-22.
[13]Gbur CJ.Stunned vs hibernating myocardium[J].JAMA,1990,264(4):455-456.
[14]Schulz R,Heusch G.Characterization of hibernating and stunned myocardium[J].Herz,1994,19(4):189-203.
[15]Slezak J,Tribulova N,Okruhlicova L,et al.Hibernating myocardium:pathophysiology,diagnosis,and treatment[J].Can J PhysiolPharmacol,2009,87(4):252-265.
[16]Cremer P,Hachamovitch R,Tamarappoo B.Clinical decision making with myocardial perfusion imaging in patients with known or suspected coronary artery disease[J].Semin Nucl Med,2014,44(4):320-329.
[17]Fuchs TA,Ghadri JR,Stehli J,et al.Hypodense regions in unenhanced CT identify nonviable myocardium:validation versus 18FFDG PET[J].Eur J Nucl Med Mol Imaging,2012,39(12):1920-1926.
[18]Bonow RO,Dilsizian V,Cuocolo A,et al.Identification of viable myocardium in patients with chronic coronary artery disease and left ventricular dysfunction.Comparison of thallium scintigraphy with reinjection and PET imaging with 18F-fluorodeoxyglucose[J].Circulation,1991,83(1):26-37.
[19]Segall G.Assessment of myocardial viability by positron emission tomography[J].Nucl Med Commun,2002,23(4):323-330.
[20]D'Egidio G,Nichol G,Williams KA,et al.Increasing benefit from revascularization is associated with increasing amounts of myocardial hibernation:a substudy of the PARR-2 trial[J].JACC Cardiovasc Imaging,2009,2(9):1060-1068.
[21]Beanlands RS,Nichol G,Huszti E,et al.F-18-fluorodeoxyglucose positron emission tomography imaging-assisted management of patients with severe left ventricular dysfunction and suspected coronary disease:a randomized,controlled trial(PARR-2)[J].J Am Coll Cardiol,2007,50(20):2002-2012.
[22]Ling LF,Marwick TH,Flores DR,et al.Identification of therapeutic benefit from revascularization in patients with left ventricular systolic dysfunction:inducible ischemia versus hibernating myocardium[J].Circ Cardiovasc Imaging,2013,6(3):363-372.
[23]Glaveckaite S,Valeviciene N,Laucevicius A,et al.Cardiovascular magnetic resonance imaging for detection of myocardial viability in chronic ischemic left ventricular dysfunction[J].Medicina(Kaunas),2009,45(8):585-599.
[24]Karamitsos TD,Dall'Armellina E,Choudhury RP,et al.Ischemic heart disease:comprehensive evaluation by cardiovascular magnetic resonance[J].Am Heart J,2011,162(1):16-30.
[25]Allman KC.Noninvasive assessment myocardial viability:current status and future directions[J].J Nucl Cardiol,2013,20(4):618-637.
[26]Partington SL,Kwong RY,Dorbala S.Multimodality imaging in the assessment of myocardial viability[J].Heart Fail Rev,2011,16(4):381-395.
[27]Baer FM,Voth E,LaRosée K,et al.Comparison of dobutamine transesophageal echocardiography and dobutamine magnetic resonance imaging for detection of residual myocardial viability[J].Am J Cardiol,1996,78(4):415-419.
[28]Baer FM,Theissen P,Schneider CA,et al.Dobutamine magnetic resonance imaging predicts contractile recovery of chronically dysfunctional myocardium after successful revascularization[J].J Am Coll Cardiol,1998,31(5):1040-1048.
[29]Schmidt M,Voth E,Schneider CA,et al.F-18-FDG uptake is a reliable predictory of functional recovery of akinetic but viable infarct regions as defined by magnetic resonance imaging before and after revascularization[J].MagnReson Imaging,2004,22(2):229-236.
[30]Nacif MS,Rochitte CE.Cardiovascular Computed Tomography and Magnetic Resonance:History and Growing Impact in Brazil and in the World[J].Arq Bras Cardiol,2014,103(5):362-367.
[31]Gai ND,Rochitte C,Nacif MS,et al.Optimized three-dimensional sodium imaging of the human heart on a clinical 3T scanner[J].MagnReson Med,2015,73(2):623-632.
[32]Mc Namara MT,Tscholakoff D,Revel D,et al.Differentiation of reversible and irreversible myocardial injury by MR imaging with and without gadolinium-DTPA[J].Radiology,1986,158(3):765-769.
[33]Kim RJ,Fieno DS,Parrish TB,et al.Relationship of MRI delayed contrast enhancement to irreversible injury,infarct age,and contractile function[J].Circulation,1999,100(19):1992-2002.
[34]Simonetti OP,Kim RJ,Fieno DS,et al.An improved MR imaging technique for the visualization of myocardial infarction[J].Radiology,2001,218(1):215-223.
[35]Rehwald WG,Kim RJ,Simonetti OP,et al.Theory of high-speed MR imaging of the human heart with the selective line acquisition mode[J].Radiology,2001,220(2):540-547.
[36]Schwitter J,Arai AE.Assessment of cardiac ischaemia and viability:role of cardiovascular magnetic resonance[J].Eur Heart J,2011,32(7):799-809.
[37]Romero J,Xue X,Gonzalez W,et al.CMR imaging assessing viability in patients with chronic ventricular dysfunction due to coronary artery disease:a meta-analysis of prospective trials[J].JACC Cardiovasc Imaging,2012,5(5):494-508.
[38]Baer FM,Voth E,Deutsch HJ,et al.Assessment of viable myocardium by dobutamine transesophageal echocardiography and comparison with fluorine-18 fluorodeoxyglucose positron emission tomography[J].J Am Coll Cardiol,1994,24(2):343-353.
[39]Mulvagh SL.Advances in myocardial contrast echocardiography and the role of adenosine stress[J].Am J Cardiol,2004,94(2A):12D-17D.
[40]Mulvagh SL.Myocardial perfusion by contrast echocardiography:diagnosis of coronary artery disease using contrast-enhanced stress echocardiography and assessment of coronary anatomy and flow reserve[J].Coron Artery Dis,2000,11(3):243-251.
[41]Swinburn JM,Lahiri A,Senior R.Intravenous myocardial contrast echocardiography predicts recovery of dysynergic myocardium early after acute myocardial infarction[J].J Am Coll Cardiol,2001,38(1):19-25.
[42]Korosoglou G,Hansen A,Hoffend J,et al.Comparison of real-time myocardial contrast echocardiography for the assessment of myocardial viability with fluorodeoxyglucose-18 positron emission tomography and dobutamine stress echocardiography[J].Am J Cardiol,2004,94(5):570-576.
[43]Elhendy A,O'Leary EL,Xie F,et al.Comparative accuracy of realtime myocardial contrast perfusion imaging and wall motion analysis during dobutamine stress echocardiography for the diagnosis of coronary artery disease[J].J Am Coll Cardiol,2004,44(11):2185-2191.
[44]Masugata H,Lafitte S,Peters B,et al.Comparison of real-time and intermittent triggered myocardial contrast echocardiography for quantification of coronary stenosis severity and transmural perfusion gradient[J].Circulation,2001,104(13):1550-1556.