2006-2016年郑州市丙型病毒性肝炎流行病学特征
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摘要
目的分析郑州市丙型病毒性肝炎(简称丙肝)流行病学特征和发病趋势。方法采用描述性流行病学方法对郑州市2006-2016年丙肝疫情数据进行分析。结果 2006-2012年郑州市丙肝报告病例数逐年增加(χ_(趋势)~2=8632.96,P<0.001),2012年报告病例数达到高峰,报告发病率高达72.10/10万;2012-2016年报告病例数及报告发病率逐年降低(χ~2趋势=711.86,P<0.001),2016年报告发病率为44.49/10万。郑州市各区2006-2016年每年均有病例报告,平均报告发病率为49.38/10万;城区2006-2016年每年报告发病率均高于周边县(市),差异有统计学意义(P<0.05);男女比波动为0.81:1～0.95:1,各年份女性报告发病率均高于男性,差异有统计学意义(P<0.05);郑州市丙肝报告病例年龄主要集中在中老年。结论郑州市属于丙肝高流行地区,应加强丙肝防治知识的宣传力度,规范医疗操作。
Objective To investigate the epidemiological characteristics and incidence trends of hepatitis C in the city of Zhengzhou. Method Descriptive research method was used to analyze the hepatitis C epidemic data from 2006 to 2016 in Zhengzhou. Results The reported cases increased year by year from 2006 to 2012( χ~2 trend=8 632.96, P<0.001), and reached a peak in 2012, with an incidence rate of 72.10/105. However, the reported cases and morbidity reduced year by year from 2012 to 2016(χ~2 trend=711.86, P<0.001). The incidence rate in 2016 was 44.49/105. Cases were reported every year in each district from 2006 to 2016. The reported average incidence rate in Zhengzhou was 49.38/105; the reported incidence rate in the urban area was higher than that in the surrounding counties from 2006 to 2016(P<0.05); fluctuations of male to female ratio was 0.81 : 1 ～0.95: 1. The reported incidence rate of females was higher than that of males in each year(P<0.05). The age of onset of hepatitis C in Zhengzhou was mainly concentrated in middle-aged and elderly people.Conclusions Zhengzhou city is a high-population area of hepatitis C. It should strengthen the propaganda of hepatitis C prevention and control knowledge and standardize medical operations.
Objective To investigate the epidemiological characteristics and incidence trends of hepatitis C in the city of Zhengzhou. Method Descriptive research method was used to analyze the hepatitis C epidemic data from 2006 to 2016 in Zhengzhou. Results The reported cases increased year by year from 2006 to 2012( χ~2 trend=8 632.96, P<0.001), and reached a peak in 2012, with an incidence rate of 72.10/105. However, the reported cases and morbidity reduced year by year from 2012 to 2016(χ~2 trend=711.86, P<0.001). The incidence rate in 2016 was 44.49/105. Cases were reported every year in each district from 2006 to 2016. The reported average incidence rate in Zhengzhou was 49.38/105; the reported incidence rate in the urban area was higher than that in the surrounding counties from 2006 to 2016(P<0.05); fluctuations of male to female ratio was 0.81 : 1 ～0.95: 1. The reported incidence rate of females was higher than that of males in each year(P<0.05). The age of onset of hepatitis C in Zhengzhou was mainly concentrated in middle-aged and elderly people.Conclusions Zhengzhou city is a high-population area of hepatitis C. It should strengthen the propaganda of hepatitis C prevention and control knowledge and standardize medical operations.
引文
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[13]赵庆龙,吕波,李美娜,等.1997-2012年吉林省丙型病毒性肝炎流行病学特征分析[J].中华疾病控制杂志,2014,18(7):594-596.
[14]陈兵,袁倩,钟璋平,等.2006-2015年深圳市宝安区丙型肝炎流行特征分析[J].医学理论与实践,2016,29(19):3417-3419.
[15]岑小莉,郭广文,甄毅燕.2004-2013年恩平市丙型病毒性肝炎流行特征及趋势分析[J].热带医学杂志,2014,14(12):1640-1642.
[16]中华人民共和国国家卫生与健康委员会.2016年全国法定传染病疫情概况[EB/OL].2017.
[2]蒋和宏,卢戎戎,罗琳,等.重庆市2004-2014年丙型病毒性肝炎流行病学分析[J].中国艾滋病性病,2017,23(1):60-62.
[3]王勇,高福,杨文钊,等.2012年中国法定传染病报告及其报告[M].北京:中国疾病预防控制中心,2013.
[4]Qin Q,Smith MK,Wang L,et al.Hepatitis C virus infection in China:an emerging public health issue[J].J Viral Hepat,2015,22(3):238-244.
[5]孙海泉,肖革新,郭莹,等.中国2008-2012年丙肝流行规律及空间聚集性分析[J].中国公共卫生,2014,30(3):286-289.
[6]李敏.中国血液制品行业分析[J].中国生物工程杂志,2016,36(9):119-125.
[7]肖达勇,李勤,唐小清,等.2007-2011年重庆市丙型病毒性肝炎流行特征分析[J].热带医学杂志,2016,16(9):1198-1200.
[8]刘源,刘富强,陈立章,等.湖南省2010-2015年丙型肝炎发病流行病学特征与短期发病趋势预测[J].中华疾病控制杂志,2017,21(2):146-150.
[9]李洁,杨文杰,王哲.河南省2004-2012年丙型肝炎流行特征分析[J].中国公共卫生,2015,31(8):1066-1068.
[10]谭超,王学燕,陈钦艳,等.2004-2015年广西丙型病毒性肝炎流行病学特征分析[J].应用预防医学,2016,22(4):321-323.
[11]刘炜炜,胡跃华,于石成,等.中国大陆地区2008-2013年丙肝发病时空聚集性及社会经济影响因素[J].中国公共卫生,2016,32(4):482-487.
[12]李凤,寇玲玲,刘继锋.2005-2015年西安市丙型肝炎流行特征分析[J].现代预防医学,2016,43(21):3862-3864,3879.
[13]赵庆龙,吕波,李美娜,等.1997-2012年吉林省丙型病毒性肝炎流行病学特征分析[J].中华疾病控制杂志,2014,18(7):594-596.
[14]陈兵,袁倩,钟璋平,等.2006-2015年深圳市宝安区丙型肝炎流行特征分析[J].医学理论与实践,2016,29(19):3417-3419.
[15]岑小莉,郭广文,甄毅燕.2004-2013年恩平市丙型病毒性肝炎流行特征及趋势分析[J].热带医学杂志,2014,14(12):1640-1642.
[16]中华人民共和国国家卫生与健康委员会.2016年全国法定传染病疫情概况[EB/OL].2017.