新型全自动显色生物芯片杂交仪的设计与实现
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摘要
针对目前市场上生物芯片杂交设备存在的通量低,不进液,反应温度控制不精准等问题,该文设计完成了一款高通量(一次反应24片)全自动显色生物芯片杂交反应设备。该设备使用注射泵完成试剂自动加取;通过自适应密封反应舱有效地解决了试剂泄漏;通过对温控软件的改进,提高了控温的精度和稳定性。该文介绍了新型设备的硬件系统和软件系统。经温度控制与液体输送性能试验表明,该设备实现了设计目标。
In this study,a high-flux( 24 pieces for a reaction),full-automatic color-rendering biochip hybridization equipment was designed in order to overcome the existing problems of low flux,lack of liquid inlet and inaccurate temperature control of the biochip hybridization equipment on the market. Injection pump was used in this equipment to complete automatic addition and removal of reagents,and the problem of reagent leakage was effectively solved by using adaptive sealing reaction chamber. Additionally,the accuracy and stability of temperature control were promoted by improving the temperature-controlled software. The details of the hardware system and software system of the new equipment were introduced in this paper. The design goals of the equipment were proved to be achieved through temperature control and liquid transport performance tests.
In this study,a high-flux( 24 pieces for a reaction),full-automatic color-rendering biochip hybridization equipment was designed in order to overcome the existing problems of low flux,lack of liquid inlet and inaccurate temperature control of the biochip hybridization equipment on the market. Injection pump was used in this equipment to complete automatic addition and removal of reagents,and the problem of reagent leakage was effectively solved by using adaptive sealing reaction chamber. Additionally,the accuracy and stability of temperature control were promoted by improving the temperature-controlled software. The details of the hardware system and software system of the new equipment were introduced in this paper. The design goals of the equipment were proved to be achieved through temperature control and liquid transport performance tests.
引文
[1]张文毓.生物芯片产业发展现状及展望[J].传感器世界,2007,13(10):6-10.
[2]沈亚斌,张晨东,赵涛.多通道微量注射泵控制系统的设计[J].计算机测量与控制,2014,22(10):32220-32222.
[3]林海波,王晓曦,刘奭昕.一种基于增量式数字PID算法的智能温度控制器[J].信息技术及应用,2011(3):86-89.
[4]车忠志,孙雪雁. MFC应用程序基本框架分析[J].农业网络信息,2010(9):145-147.
[2]沈亚斌,张晨东,赵涛.多通道微量注射泵控制系统的设计[J].计算机测量与控制,2014,22(10):32220-32222.
[3]林海波,王晓曦,刘奭昕.一种基于增量式数字PID算法的智能温度控制器[J].信息技术及应用,2011(3):86-89.
[4]车忠志,孙雪雁. MFC应用程序基本框架分析[J].农业网络信息,2010(9):145-147.