WHO(2017)头颈部肿瘤(下咽、喉、气管及咽旁间隙肿瘤)分类解读
摘要
<正>下咽、喉、气管及咽旁间隙解剖学上相连,功能上相辅,一旦发生肿瘤则可彼此相损。国际癌症研究机构(IARC)2017年2月发行的第4版《WHO头颈部肿瘤分类》~([1])(简称新版)与WHO(2005)分类~([2])(简称旧版)相比,重点介绍了黏膜前驱病变;将恶性上皮性肿瘤最常见的、经典的组织学类型命名为普通型鳞状细胞癌(conventional squamous cell
引文
[1]El-Naggar A K,Chan J K C,Grandis J R,et al.WHO classification of tumors of head and neck tumours[M].4th ed.Lyon:IARCPress,2017:77-104.
[2]Barnes L,Eveson J W,Reichart P,et al.WHO pathology and genetics classification of tumors of head and neck tumours[M].3rd ed.Lyon:IARC Press,2005:107-162.
[3]Gale N,Blagus R,El-Mofty S K,et al.Evaluation of a new grading system for laryngeal squamous intraepithelial lesions---a proposed unified classification[J].Histopathology,2014,65(4):456-464.
[4]Gale N,Gnepp D R,Poljak M,et al.Laryngeal squamous intraepithelial lesions:an updated review on etiology,classification,molecular changes,and treatment[J].Adv Anat Pathol,2016,23(2):84-91.
[5]Gale N,Poljak M,Zidar N.Update from the 4th edition of the World Health Organization classification of head and neck tumours:what is new in the 2017 who blue book for tumours of the hypopharynx,larynx,trachea and parapharyngeal space[J].Head Neck Pathol,2017,11(1):23-32.
[6]Hunt J L,Ferlito A,Hellquist H,et al.Differential diagnosis in neuroendocrine neoplasms of the larynx[J].Adv Anat Pathol,2017,24(3):161-168.
[7]Agaimy A,Weichert W.Grading of head and neck neoplasms[J].Pathologe,2016,37(4):285-292.
[8]Sarioglu S,Acara C,Akman F C,et al.Tumor budding as a prognostic marker in laryngeal carcinoma[J].Pathol Res Pract,2010,206(2):88-92.
[9]Hori Y,Kubota A,Yokose T,et al.Predictive significance of tumor depth and budding for late lymph node metastases in patients with clinical N0 early oral tongue carcinoma[J].Head Neck Pathol,2017,11(4):477-486.
[10]Hellquist H,Cardesa A,Gale N,et al.Criteria for grading in the ljubljana classification of epithelial hyperplastic laryngeal lesions.A study by members of the working group on epithelial hyperplastic laryngeal lesions of the european society of pathology[J].Histopathology,1999,34(3):226-233.
[11]Gale N,Gnepp D R,Poljak M,et al.Laryngeal squamous intraepithelial lesions:an updated review on etiology,classification,molecular changes,and treatment[J].Adv Anat Pathol,2016,23(2):84-91.
[12]López F,Williams M D,Cardesa A,et al.How phenotype guides management of non-conventional squamous cell carcinomas of the larynx?[J].Eur Arch Otorhinolaryngol,2017,274(7):2709-2726.
[13]Thompson L D.Laryngeal dysplasia,squamous cell carcinoma,and variants[J].Surg Pathol Clin,2017,10(1):15-33.
[14]Riener M O,Hoegel J,Iro H,et al.IMP3 and p16 expression in squamous cell carcinoma of the head and neck:a comparative immunohistochemical analysis[J].Oncol Lett,2017,14(2):1665-1670.
[15]Sánchez Barrueco A,González Galán F,Lora Pablos D,et al.HPV in larynx squamous cell carcinoma:new serotypes and survival study within 10-year follow-up[J].Otolaryngol Head Neck Surg,2017,156(4):677-682.
[16]Dunn A,Broadfoot B G,Hunt J,et al.Metastatic laryngeal large cell neuroendocrine carcinoma:a rare case of presentation and extreme tumor burden[5].J Cutan Pathol,2018,45(3):229-233.
[17]Thompson E D,Stelow E B,Mills S E,et al.Large cell neuroendocrine carcinoma of the head and neck:a clinicopathologic series of 10 cases with an emphasis on HPV status[J].Am J Surg Pathol,2016,40(4):471-478.
[18]Fletcher C D M,Bridge J A,Hogendoorn P,et al.World Health Organization classification of tumours of soft tissue and bone[M].4th ed.Lyon:IARC Press,2013:264-268.
[19]Chin O Y,Dubal P M,Sheikh A B,et al.Laryngeal chondrosarcoma:a systematic review of 592 cases[J].Laryngoscope,2017,127(2):430-439.
[2]Barnes L,Eveson J W,Reichart P,et al.WHO pathology and genetics classification of tumors of head and neck tumours[M].3rd ed.Lyon:IARC Press,2005:107-162.
[3]Gale N,Blagus R,El-Mofty S K,et al.Evaluation of a new grading system for laryngeal squamous intraepithelial lesions---a proposed unified classification[J].Histopathology,2014,65(4):456-464.
[4]Gale N,Gnepp D R,Poljak M,et al.Laryngeal squamous intraepithelial lesions:an updated review on etiology,classification,molecular changes,and treatment[J].Adv Anat Pathol,2016,23(2):84-91.
[5]Gale N,Poljak M,Zidar N.Update from the 4th edition of the World Health Organization classification of head and neck tumours:what is new in the 2017 who blue book for tumours of the hypopharynx,larynx,trachea and parapharyngeal space[J].Head Neck Pathol,2017,11(1):23-32.
[6]Hunt J L,Ferlito A,Hellquist H,et al.Differential diagnosis in neuroendocrine neoplasms of the larynx[J].Adv Anat Pathol,2017,24(3):161-168.
[7]Agaimy A,Weichert W.Grading of head and neck neoplasms[J].Pathologe,2016,37(4):285-292.
[8]Sarioglu S,Acara C,Akman F C,et al.Tumor budding as a prognostic marker in laryngeal carcinoma[J].Pathol Res Pract,2010,206(2):88-92.
[9]Hori Y,Kubota A,Yokose T,et al.Predictive significance of tumor depth and budding for late lymph node metastases in patients with clinical N0 early oral tongue carcinoma[J].Head Neck Pathol,2017,11(4):477-486.
[10]Hellquist H,Cardesa A,Gale N,et al.Criteria for grading in the ljubljana classification of epithelial hyperplastic laryngeal lesions.A study by members of the working group on epithelial hyperplastic laryngeal lesions of the european society of pathology[J].Histopathology,1999,34(3):226-233.
[11]Gale N,Gnepp D R,Poljak M,et al.Laryngeal squamous intraepithelial lesions:an updated review on etiology,classification,molecular changes,and treatment[J].Adv Anat Pathol,2016,23(2):84-91.
[12]López F,Williams M D,Cardesa A,et al.How phenotype guides management of non-conventional squamous cell carcinomas of the larynx?[J].Eur Arch Otorhinolaryngol,2017,274(7):2709-2726.
[13]Thompson L D.Laryngeal dysplasia,squamous cell carcinoma,and variants[J].Surg Pathol Clin,2017,10(1):15-33.
[14]Riener M O,Hoegel J,Iro H,et al.IMP3 and p16 expression in squamous cell carcinoma of the head and neck:a comparative immunohistochemical analysis[J].Oncol Lett,2017,14(2):1665-1670.
[15]Sánchez Barrueco A,González Galán F,Lora Pablos D,et al.HPV in larynx squamous cell carcinoma:new serotypes and survival study within 10-year follow-up[J].Otolaryngol Head Neck Surg,2017,156(4):677-682.
[16]Dunn A,Broadfoot B G,Hunt J,et al.Metastatic laryngeal large cell neuroendocrine carcinoma:a rare case of presentation and extreme tumor burden[5].J Cutan Pathol,2018,45(3):229-233.
[17]Thompson E D,Stelow E B,Mills S E,et al.Large cell neuroendocrine carcinoma of the head and neck:a clinicopathologic series of 10 cases with an emphasis on HPV status[J].Am J Surg Pathol,2016,40(4):471-478.
[18]Fletcher C D M,Bridge J A,Hogendoorn P,et al.World Health Organization classification of tumours of soft tissue and bone[M].4th ed.Lyon:IARC Press,2013:264-268.
[19]Chin O Y,Dubal P M,Sheikh A B,et al.Laryngeal chondrosarcoma:a systematic review of 592 cases[J].Laryngoscope,2017,127(2):430-439.