摘要
目的探究130例慢性肾脏病CKD5期患者应用腹膜透析治疗的临床疗效。方法 2017年1月—2018年1月为该次研究时段,方便选取130例该院在研究时段内收治的慢性肾脏病CKD5期患者作为研究目标,采用计算机随机分组法,将研究目标分为对照组、治疗组,每组样本均65例,血液透析治疗措施应用于对照中,腹膜透析治疗措施应用于治疗组中,分析两组治疗总有效率、 C反应蛋白水平、营养指标、临床指标。结果治疗组治疗总有效率95.4%高于对照组81.5%(χ~2=6.104,P=0.013);治疗6个月后C反应蛋白水平治疗组(13.64±3.17)mg/L低于对照组(23.44±3.51)mg/L(t=16.705,P=0.000);相较于对照组,营养指标、临床指标治疗组较优(P<0.05)。结论腹膜透析治疗措施应用于慢性肾脏病CKD5期患者中,既可改善临床指标及营养水平,又可降低C反应蛋白水平、提高治疗总有效率,临床应用效果显著,值得临床推广。
Objective To explore the clinical effect of peritoneal dialysis in 130 patients with CKD5 chronic kidney disease.Methods From January 2017 to January 2018, 130 patients with CKD5 chronic kidney disease admitted to our hospital during the study period were convenient divided into control group and treatment group by computer random grouping method.Each group had 65 samples. Hemodialysis treatment measures were applied in the control group. Peritoneal dialysis of treatment measures were applied in the treatment group. The total effective rate of treatment, C-reactive protein level, nutritional indicators, clinical indicators were analyzed. Results The total effective rate of treatment group was 95.4%, which was higher than that of the control group 81.5%(χ~2=6.104, P=0.013). After 6 months of treatment, the C-reactive protein level of the treatment group(13.64±3.17)mg/L was lower than that of the control group(23.44±3.51)mg/L(t=16.705,P=0.000). Compared with the control group, the nutritional index and clinical index in the treatment group were better(P<0.05). Conclusion The application of peritoneal dialysis in CKD5 patients with chronic kidney disease can not only improve the clinical indicators and nutritional level, but also reduce the level of C-reactive protein and improve the total effective rate of treatment. The clinical application effect is remarkable, which is worthy of clinical promotion.
引文
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