针灸联合激光治疗对骨质疏松患者后腰背痛的影响
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摘要
目的:探究针灸联合激光治疗改善骨质疏松患者后腰背痛的效果。方法:将59例患者随机分为观察组30例、对照组29例,2组均给予常规治疗,对照组同时给予针灸治疗,观察组在对照组治疗的基础上加用激光治疗,2组均连续治疗28天。观察2组治疗前后视觉模拟评分(VAS)、骨密度及血清基质金属蛋白酶2(MMP-2)和血清I型前胶原氨基端前肽(PINP)水平的变化情况。结果:VAS评分2组均随着治疗时间的增多而降低,差异有统计学意义(P<0.05);治疗后相同时间点2组比较,差异有统计学意义(P<0.05)。骨密度及血清MMP-2、PINP水平治疗前后2组组内比较,差异有统计学意义(P<0.05);治疗后2组组间比较差异也有统计学意义(P<0.05)。结论:针灸联合激光治疗在改善骨质疏松患者后腰背痛方面具有积极意义。
Objective:To discuss the effects of acupuncture and laser therapy in improving back pain of the patients with osteoporosis. Methods: All 59 patients were randomized into the observation group(30 cases) and the control group( 29 cases), both groups accepted routine therapy, the control group were treated by acupuncture, the observation group accepted laser on the foundation of acupuncture, both groups were treated for 28 days consecutively. The changes of VAS, bone density, MMP-2 and PINP of both groups were observed before and after treating. Results: VAS of both groups decreased as therapeutic time increased, and the difference had statistical meaning(P<0.05); the difference had statistical meaning in the comparisons of the same time after treating between both groups(P<0.05). The difference showed statistical meaning in the comparisons of bone density, the levels of MMP-2 and PINP within two groups before and after treating(P<0.05); the difference was statistically significant in the comparison between both groups after treating( P < 0.05). Conclusion: Acupuncture and laser therapy are meaningful in improving back pain of the patients with osteoporosis.
Objective:To discuss the effects of acupuncture and laser therapy in improving back pain of the patients with osteoporosis. Methods: All 59 patients were randomized into the observation group(30 cases) and the control group( 29 cases), both groups accepted routine therapy, the control group were treated by acupuncture, the observation group accepted laser on the foundation of acupuncture, both groups were treated for 28 days consecutively. The changes of VAS, bone density, MMP-2 and PINP of both groups were observed before and after treating. Results: VAS of both groups decreased as therapeutic time increased, and the difference had statistical meaning(P<0.05); the difference had statistical meaning in the comparisons of the same time after treating between both groups(P<0.05). The difference showed statistical meaning in the comparisons of bone density, the levels of MMP-2 and PINP within two groups before and after treating(P<0.05); the difference was statistically significant in the comparison between both groups after treating( P < 0.05). Conclusion: Acupuncture and laser therapy are meaningful in improving back pain of the patients with osteoporosis.
引文
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[10]唐颂军,宋力轶,朱文峰,等.骨转换标志物PINP和β-CTX的测定在预测骨质疏松性骨折中的价值[J].实用临床医药杂志,2015,19(21):17-19.
[11]禇青波.骨质疏松患者血清MMP相关指标及骨胶原指标的变化研究[J].陕西医学杂志,2017,46(5):619-620.
[12] Gordon C,Harvey P R,Mazumdar S,et al.290.Long-Term outcome of treatment with mycophenolate mofetil for lupus nephritis[J].Rheumatology,2015,54(suppl 1):162-163.
[13] Moon PD,Kim MH,Oh HA,et al.Cysteine induces longitudinal bone growth in mice by upregulating IGF-I[J].International Journal of Molecular Medicine,2015,36(2):571-580.
[14]李金艳,陈颖,唐艳丽,等.针灸治疗骨质疏松症效应机制研究进展[J].中国骨质疏松杂志,2014,20(3):315-321.
[15]乔思雨,赵英侠.针灸治疗绝经后骨质疏松症的实验研究进展[J].中国骨质疏松杂志,2015,21(10):1258-1262.
[16]Cheng Z,Wang J,Zheng Q,et al.Anterolateral radical debridement and interbody bone grafting combined with transpedicle fixation in the treatment of thoracolumbar spinal tuberculosis[J].Medicine,2015,94(14):721-740.
[17]覃飞,张馨蕾,阮洋,等.低强度激光和有氧运动对大鼠围绝经期骨结构和骨代谢的影响[J].体育学刊,2013,20(6):126-131.
[18]侯海斌,史盛梅.低强度激光治疗联合有氧运动治疗骨质疏松的临床研究[J].中国骨质疏松杂志,2015,21(8):938-940.
[2]乔芳,常静.骨质疏松流行病学调查分析[J].中国实用医药,2012,7(30):271-272.
[3]张智海,刘忠厚,李娜,等.中国人骨质疏松症诊断标准专家共识(第三稿·2014版)[J].中国骨质疏松杂志,2014,20(9):1007-1010.
[4]郭永兰.VAS评分在腰椎间盘突出症术后护理中应用[J].交通医学,2014,28(4):403-404.
[5]胥少汀,葛宝丰.实用骨科学[M].北京:人民军医出版社,2005:178.
[6]李非,李红专,叶丙霖.原发性骨质疏松症的中医药研究现状[J].西部中医药,2016,29(3):136-139.
[7] Dydykina P,Petrova E,Dydykina I,et al.AB0383 the influence of denosumab on bone mineral density,structural damage in patients with osteoporosis and rheumatoid arthritis[J].Annals of the Rheumatic Diseases,2015,74(Suppl 2):1021-1037.
[8]Karagülle M,Karde S,Dii R,et al.Spa therapy for elderly:a retrospective study of 239 older patients with osteoarthritis[J].International Journal of Biometeorology,2016,60(10):1-11.
[9]王亚春,孙绍骞,王锐,等.雌激素和骨标志物与绝经后妇女骨质疏松的关系[J].中国妇幼保健,2015,30(27):4675-4676.
[10]唐颂军,宋力轶,朱文峰,等.骨转换标志物PINP和β-CTX的测定在预测骨质疏松性骨折中的价值[J].实用临床医药杂志,2015,19(21):17-19.
[11]禇青波.骨质疏松患者血清MMP相关指标及骨胶原指标的变化研究[J].陕西医学杂志,2017,46(5):619-620.
[12] Gordon C,Harvey P R,Mazumdar S,et al.290.Long-Term outcome of treatment with mycophenolate mofetil for lupus nephritis[J].Rheumatology,2015,54(suppl 1):162-163.
[13] Moon PD,Kim MH,Oh HA,et al.Cysteine induces longitudinal bone growth in mice by upregulating IGF-I[J].International Journal of Molecular Medicine,2015,36(2):571-580.
[14]李金艳,陈颖,唐艳丽,等.针灸治疗骨质疏松症效应机制研究进展[J].中国骨质疏松杂志,2014,20(3):315-321.
[15]乔思雨,赵英侠.针灸治疗绝经后骨质疏松症的实验研究进展[J].中国骨质疏松杂志,2015,21(10):1258-1262.
[16]Cheng Z,Wang J,Zheng Q,et al.Anterolateral radical debridement and interbody bone grafting combined with transpedicle fixation in the treatment of thoracolumbar spinal tuberculosis[J].Medicine,2015,94(14):721-740.
[17]覃飞,张馨蕾,阮洋,等.低强度激光和有氧运动对大鼠围绝经期骨结构和骨代谢的影响[J].体育学刊,2013,20(6):126-131.
[18]侯海斌,史盛梅.低强度激光治疗联合有氧运动治疗骨质疏松的临床研究[J].中国骨质疏松杂志,2015,21(8):938-940.