子痫前期胎儿主动脉峡部血流指数与胎儿不良围产结局关系的临床研究
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摘要
目的探讨胎儿AoI-IFI及其他多普勒血流参数与胎儿不良围产结局的关系及意义。方法将PE孕妇与正常孕妇按孕周1∶1配对,采用散点图分析二者胎儿的AoI-IFI、AoI-PSV、CPR值的分布。采用卡方检验评估AoI-IFI、CPR、UA多普勒参数对胎儿不良围产结局的诊断价值。将胎儿血流多普勒参数与围产结局联合,通过诊断试验,对各参数的灵敏度、特异度进行比较。结果 (1)PE孕妇胎儿AoI-IFI、AoI-PSV、CPR低于正常孕妇胎儿,差异具有统计学意义(P<0.05)。(2)AoI-IFI与CPR、UA相比诊断价值更大,差异具有统计学意义(P<0.05)。(3)AoI-IFI对于预测胎儿围产结局不良的灵敏度最高。结论胎儿AoI-IFI与其他指标相比对IUGR诊断价值更大,预测胎儿围产结局不良的灵敏度最高。
Objective To explore the relationship between fetal AoI-IFI and other doppler blood flow parameters with fetal adverse perinatal outcomes.Methods Match preeclampsia pregnant women and normal pregnant women at1∶1 paired by gestational week.The AoI-IFI,AoI-PSV and CPR of normal and preeclampsia fetuses were analyzed by scatter plot.Chi-square test was used to evaluate the diagnostic value of doppler blood flow parameters in fetal adverse perinatal outcomes.The fetal blood flow doppler parameters were combined with the fetal perinatal outcome.The sensitivity and specificity of the parameters were analyzed and compared by diagnostic test.Results(1)Preeclampsia′s AoI-IFI,AoI-PSV,CPR are lower than the normal fetus,and the difference is statistically significant(P<0.05).(2)Fetal AoI-IFI is more valuable than CPR and UA,and the difference is statistically significant(P<0.05).(3)Fetal AoI-IFI has the highest sensitivity in the predictive of fetal perinatal maloutcome.Conclusions Compared with other parameters,fetal AoI-IFI has the greatest diagnostic value.Fetal AoI-IFI has the highest sensitivity in the predictive of fetal perinatal outcome.
Objective To explore the relationship between fetal AoI-IFI and other doppler blood flow parameters with fetal adverse perinatal outcomes.Methods Match preeclampsia pregnant women and normal pregnant women at1∶1 paired by gestational week.The AoI-IFI,AoI-PSV and CPR of normal and preeclampsia fetuses were analyzed by scatter plot.Chi-square test was used to evaluate the diagnostic value of doppler blood flow parameters in fetal adverse perinatal outcomes.The fetal blood flow doppler parameters were combined with the fetal perinatal outcome.The sensitivity and specificity of the parameters were analyzed and compared by diagnostic test.Results(1)Preeclampsia′s AoI-IFI,AoI-PSV,CPR are lower than the normal fetus,and the difference is statistically significant(P<0.05).(2)Fetal AoI-IFI is more valuable than CPR and UA,and the difference is statistically significant(P<0.05).(3)Fetal AoI-IFI has the highest sensitivity in the predictive of fetal perinatal maloutcome.Conclusions Compared with other parameters,fetal AoI-IFI has the greatest diagnostic value.Fetal AoI-IFI has the highest sensitivity in the predictive of fetal perinatal outcome.
引文
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[2]中华医学会急诊学分会儿科学组.新生儿危重病例评分法(草案)[J].中国实用儿科杂志,2001,16(11):694-695.
[3]刘彩娥,吉旭姣,薛亚丽,等.超声检测妊娠期高血压疾病患者胎儿主动脉峡部收缩指数的意义[J].中国超声医学杂志,2018,34(7):641-644.
[4] TYNAN D,ALPHONSE J,HENRY A,et al.The Aortic Isthmus:A Significant yet Underexplored Watershed of the Fetal Circulation[J].Fetal Diagnosis&Therapy,2016,40(2):81-93.