登革热病毒分子生物学特性及检测方法研究进展
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摘要
登革热病毒可以引起登革热、登革出血热和登革休克综合征,主要流行于热带、亚热带地区。近年来,登革热病毒流行范围不断扩大,严重危害人类健康。该文对登革热病毒的分子生物学特性和检测方法的研究进展进行了综述。
Dengue virus can cause dengue fever, dengue hemorrhagic fever, and dengue shock syndrome, which is mainly endemic in tropical and subtropical regions. The epidemic area of Dengue virus has been increasing in recent years, which seriously endangers human health. This paper reviews the research progress in molecular biological characteristics and detection methods of Dengue virus.
Dengue virus can cause dengue fever, dengue hemorrhagic fever, and dengue shock syndrome, which is mainly endemic in tropical and subtropical regions. The epidemic area of Dengue virus has been increasing in recent years, which seriously endangers human health. This paper reviews the research progress in molecular biological characteristics and detection methods of Dengue virus.
引文
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[16]吴忠华,罗鹏,徐琦,等.登革病毒检测技术研究进展[J].生物技术通讯,2013(5):727-731.DOI:10.3969/j.issn.1009-0002.2013.05.030.
[17]盛琳君,李昂,张福杰,等.黄热病病毒检测方法研究进展[J].中华传染病杂志,2017,35(3):190-192.DOI:10.3760/cma.j.issn.1000-6680.2017.03.018.
[18]王艳红,宝福凯,柳爱华.登革病毒感染的检测技术研究进展[J].生命科学研究,2013,17(1):78-85.DOI:10.3969/j.issn.1007-7847.2013.01.016.
[19]Thiha A,Ibrahim F.A colorimetric Enzyme-Linked immunosorbent assay(ELISA)detection platform for a Point-of-Care dengue detection system on a Lab-on-Compact-Disc[J].Sensors,2015,15(5):11431-11441.DOI:10.3390/s150511431.
[20]Rodríguez Roche R,Alvarez M,Guzmán MG,et al.Comparison of rapid centrifugation assay with conventional tissue culture method for isolation of dengue 2 virus in C6/36-HT cells[J].JClin Microbiol,2000,38(9):3508-3510.
[21]Muller DA,Depelsenaire ACI,Young PR.Clinical and laboratory diagnosis of Dengue virus infection[J].J Infect Dis,2017,215 Suppl 2:S89-95.DOI:10.1093/infdis/jiw649.
[22]Waggoner JJ,Gresh L,Mohamed-Hadley A,et al.Single-reaction multiplex reverse transcription PCR for detection of Zika,Chikungunya,and Dengue viruses[J].Emerg Infect Dis,2016,22(7):1295-1297.DOI:10.3201/eid2207.160326.
[23]Lanciotti RS,Calisher CH,Gubler DJ,et al.Rapid detection and typing of Dengue viruses from clinical samples by using reverse transcriptase-polymerase chain reaction[J].J Clin Microbiol,1992,30(3):545-551.
[24]Waggoner JJ,Abeynayake J,Balassiano I,et al.Multiplex nucleic acid amplification test for diagnosis of dengue fever,malaria,and leptospirosis[J].J Clin Microbiol,2014,52(6):2011-2018.DOI:10.1128/JCM.00341-14.
[25]Ahmed NH,Broor S.Comparison of NS1 antigen detection ELISA,real time RT-PCR and virus isolation for rapid diagnosis of dengue infection in acute phase[J].J Vector Borne Dis,2014,51(3):194-199.
[26]Simmons M,Myers T,Guevara C,et al.Development and validation of a quantitative,one-step,multiplex,real-time RT-PCR assay for the detection of dengue and Chikungunya viruses[J].J Clin Microbiol,2016,54(7):1766-1773.DOI:10.1128/JCM.00299-16.
[27]Wu SJL,Lee EM,Putvatana R,et al.Detection of dengue viral RNA using a nucleic acid sequence-based amplification assay[J].J Clin Microbiol,2001,39(8):2794-2798.DOI:10.1128/JCM.39.8.2794-2798.2001.
[28]庄坚,郭辉玉,陈火胜.非同位素标记探针检测登革病毒RNA的研究[J].中华微生物学和免疫学杂志,1994,14(6):426-429.
[2]Guzman MG,Harris E.Dengue[J].Lancet,2015,385(9966):453-465.DOI:10.1016/S0140-6736(14)60572-9.
[3]Waggoner JJ,Gresh L,Vargas MJ,et al.Viremia and clinical presentation in Nicaraguan patients infected with Zika virus,Chikungunya virus,and Dengue virus[J].Clin Infect Dis,2016,63(12):1584-1590.DOI:10.1093/cid/ciw589.
[4]Ye Z,Huang YX,Jiang P,et al.Analysis of clinical characteristic of 158 inpatients with dengue fever in Guangzhou area during the 2014 epidemic[J].Chin Cri Care Med,2015,27(4):300-305.DOI:10.3760/cma.j.issn.2095-4352.2015.04.015.
[5]Jelinek T.Dengue fever in international travelers[J].Clin Infect Dis,2000,31(1):144-147.DOI:10.1086/313889.
[6]Murrell S,Wu SC,Butler M.Review of Dengue virus and the development of a vaccine[J].Biotechnol Adv,2011,29(2):239-247.DOI:10.1016/j.biotechadv.2010.11.008.
[7]Elghonemy S,Davis WG,Brinton MA.The majority of the nucleotides in the top loop of the genomic 3′terminal stem loop structure are cis-acting in a West Nile virus infectious clone[J].Virology,2005,331(2):238-246.DOI:10.1016/j.virol.2004.11.008.
[8]Kimura-Kuroda J,Yasui K.Antigenic comparison of envelope protein E between Japanese encephalitis virus and some other flaviviruses using monoclonal antibodies[J].J Gen Virol,1986,67(Pt 12):2663-2672.
[9]Chung KM,Nybakken GE,Thompson BS,et al.Antibodies against West Nile virus nonstructural protein NS1 prevent lethal infection through Fcγreceptor-dependent and-independent mechanisms[J].J Virol,2006,80(3):1340-1351.DOI:10.1128/JVI.80.3.1340-1351.2006.
[10]Lin CW,Huang HD,Shiu SY,et al.Functional determinants of NS2B for activation of Japanese encephalitis virus NS3 protease[J].Virus Res,2007,127(1):88-94.DOI:10.1016/j.virusres.2007.03.022.
[11]Khan F,Ahmad A,Ali A,et al.Conformational hotspots of Dengue virus NS5 Rd Rp[J].Curr Bioinform,2018,13(3):310-318.DOI:10.2174/1574893612666161214124827.
[12]Miller S,Kastner S,Krijnse-Locker J,et al.The non-structural protein 4A of Dengue virus is an integral membrane protein inducing membrane alterations in a 2K-regulated manner[J].JBiol Chem,2007,282(12):8873-8882.DOI:10.1074/jbc.M609919200.
[13]Davidson AD.New insights into Flavivirus Nonstructural protein5[J].Adv Virus Res,2009,74:41-101.DOI:10.1016/S0065-3527(09)74002-3.
[14]Lin RJ,Chang BL,Yu HP,et al.Blocking of interferon-induced Jak-Stat signaling by Japanese encephalitis virus NS5 through a protein tyrosine phosphatase-mediated mechanism[J].J Virol,2006,80(12):5908-5918.DOI:10.1128/JVI.02714-05.
[15]Jarman RG,Nisalak A,Anderson KB,et al.Factors influencing Dengue virus isolation by C6/36 cell culture and mosquito inoculation of nested PCR-positive clinical samples[J].Am JTrop Med Hyg,2011,84(2):218-223.DOI:10.4269/ajtmh.2011.09-0798.
[16]吴忠华,罗鹏,徐琦,等.登革病毒检测技术研究进展[J].生物技术通讯,2013(5):727-731.DOI:10.3969/j.issn.1009-0002.2013.05.030.
[17]盛琳君,李昂,张福杰,等.黄热病病毒检测方法研究进展[J].中华传染病杂志,2017,35(3):190-192.DOI:10.3760/cma.j.issn.1000-6680.2017.03.018.
[18]王艳红,宝福凯,柳爱华.登革病毒感染的检测技术研究进展[J].生命科学研究,2013,17(1):78-85.DOI:10.3969/j.issn.1007-7847.2013.01.016.
[19]Thiha A,Ibrahim F.A colorimetric Enzyme-Linked immunosorbent assay(ELISA)detection platform for a Point-of-Care dengue detection system on a Lab-on-Compact-Disc[J].Sensors,2015,15(5):11431-11441.DOI:10.3390/s150511431.
[20]Rodríguez Roche R,Alvarez M,Guzmán MG,et al.Comparison of rapid centrifugation assay with conventional tissue culture method for isolation of dengue 2 virus in C6/36-HT cells[J].JClin Microbiol,2000,38(9):3508-3510.
[21]Muller DA,Depelsenaire ACI,Young PR.Clinical and laboratory diagnosis of Dengue virus infection[J].J Infect Dis,2017,215 Suppl 2:S89-95.DOI:10.1093/infdis/jiw649.
[22]Waggoner JJ,Gresh L,Mohamed-Hadley A,et al.Single-reaction multiplex reverse transcription PCR for detection of Zika,Chikungunya,and Dengue viruses[J].Emerg Infect Dis,2016,22(7):1295-1297.DOI:10.3201/eid2207.160326.
[23]Lanciotti RS,Calisher CH,Gubler DJ,et al.Rapid detection and typing of Dengue viruses from clinical samples by using reverse transcriptase-polymerase chain reaction[J].J Clin Microbiol,1992,30(3):545-551.
[24]Waggoner JJ,Abeynayake J,Balassiano I,et al.Multiplex nucleic acid amplification test for diagnosis of dengue fever,malaria,and leptospirosis[J].J Clin Microbiol,2014,52(6):2011-2018.DOI:10.1128/JCM.00341-14.
[25]Ahmed NH,Broor S.Comparison of NS1 antigen detection ELISA,real time RT-PCR and virus isolation for rapid diagnosis of dengue infection in acute phase[J].J Vector Borne Dis,2014,51(3):194-199.
[26]Simmons M,Myers T,Guevara C,et al.Development and validation of a quantitative,one-step,multiplex,real-time RT-PCR assay for the detection of dengue and Chikungunya viruses[J].J Clin Microbiol,2016,54(7):1766-1773.DOI:10.1128/JCM.00299-16.
[27]Wu SJL,Lee EM,Putvatana R,et al.Detection of dengue viral RNA using a nucleic acid sequence-based amplification assay[J].J Clin Microbiol,2001,39(8):2794-2798.DOI:10.1128/JCM.39.8.2794-2798.2001.
[28]庄坚,郭辉玉,陈火胜.非同位素标记探针检测登革病毒RNA的研究[J].中华微生物学和免疫学杂志,1994,14(6):426-429.