前列腺脓肿病例报道并文献复习
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  • 英文篇名:Prostate Abscess:Case Report and Review of the Literature
  • 作者:李显永 ; 赵晖 ; 官润云 ; 顾鹏 ; 陈跃龙
  • 英文作者:LI Xianyong;ZHAO Hui;GUAN Runyun;GU Peng;CHEN Yuelong;Department of Urology,the First Affiliated Hospital of Kunming Medical University;
  • 关键词:前列腺脓肿 ; 病例报告 ; 症状和体征 ; 治疗
  • 英文关键词:Prostatic abscess;;Case reports;;Symptoms & signs;;Therapy
  • 中文刊名:QKYX
  • 英文刊名:Chinese General Practice
  • 机构:昆明医科大学第一附属医院泌尿外科;
  • 出版日期:2018-12-17
  • 出版单位:中国全科医学
  • 年:2018
  • 期:v.21;No.591
  • 基金:云南省科技计划项目(2017FE467(-042))
  • 语种:中文;
  • 页:QKYX201836028
  • 页数:6
  • CN:36
  • ISSN:13-1222/R
  • 分类号:124-129
摘要
目的探讨前列腺脓肿(PA)临床特征,为临床治疗提供参考。方法选取2005年1月—2017年10月昆明医科大学第一附属医院收治的4例PA患者,在PubMed以"prostate abscess OR prostatic abscess"为标题或关键词检索2007年11月—2017年11月相关文献并进行PA的临床特征分析。结果 4例患者中有糖尿病病史2例,导尿史1例,前列腺增生1例;1例直肠指检触及波动感;2例患者脓液细菌培养为大肠埃希菌;均经手术治疗后痊愈。文献共纳入379例PA患者,其中糖尿病(28.0%)、尿道侵入性操作(12.9%)、免疫抑制(7.1%)是PA的主要易感因素;发热(59.6%)、尿路刺激征(36.7%)、疼痛(33.5%)为主要临床表现;大肠埃希菌(26.4%)、肺炎克雷伯杆菌(13.5%)、金黄色葡萄球菌(7.1%)为常见致病菌;多数患者需手术治疗。结论 PA早期症状无特异性,诊断困难,对疑似病例应及时行经直肠B超、CT或磁共振成像(MRI)明确诊断,治疗主要以敏感抗生素、经直肠PA穿刺引流术和经尿道PA去顶引流术为主。
        Objective To explore the clinical features of prostate abscesses(PA) and provide reference for clinical treatments.Methods Four PA patients admitted to the First Affiliated Hospital of Kunming Medical University from January 2005 to October 2017 were selected to investigate the clinical features of PA.Using the PubMed database with the title or keyword "prostate abscess OR prostatic abscess" from November 2007 to November 2017.Then,we analyzed the clinical features of PA.Results Among the 4 patients,2 had a history of diabetes,1 had a history of catheterization,1 had a history of benign prostatic hyperplasia,1 had a sense of volatility following a digital rectal examination,and 2 had bacterial cultures of pus positive for Escherichia.coli.All of the patients recovered after surgery.A total of 379 PA patients were included in the literature search.Among the patients,diabetes(28.0%),urethral tract invasion(12.9%),and immunosuppression(7.1%) were the predominant susceptibility factors for PA.Fever(59.6%),urinary tract irritation(36.7%),and pain(33.5%) were the main symptoms.E.coli(26.4%),Klebsiella pneumonia(13.5%),and Staphylococcus aureus(7.1%) were common pathogens.Most of the patients required surgical intervention.Conclusion The early symptoms of PA are not specific and are difficult to diagnose.Suspected cases of PA should be promptly diagnosed using transrectal ultrasound,CT,or MRI.The treatment of PA is mainly based on sensitive antibiotics,transrectal puncture and drainage of the PA,and urethral drainage to the top of the PA.
引文
[1]GRANADOS E A,RILEY G,SALVADOR J,et al.Prostatic abscess:diagnosis and treatment[J].J Urol,1992,148(1):80-82.
    [2]OLIVEIRA P,ANDRADE J A,PORTO H C,et al.Diagnosis and treatment of prostatic abscess[J].Int Braz J Urol,2003,29(1):30-34.
    [3]JANG K,LEE D H,LEE S H,et al.Treatment of prostatic abscess:case collection and comparison of treatment methods[J].Korean J Urol,2012,53(12):860-864.DOI:10.4111/kju.2012.53.12.860.
    [4]CHOUDHRY M,PELLINO G,SIMILLIS C,et al.Prostatic abscesses.A case report and review of the literature on current treatment approaches[J].Cent European J Urol,2017,70(1):118-122.DOI:10.5173/ceju.2016.934.
    [5]EOM J H,YOON J H,LEE S W,et al.Tuberculous prostatic abscess with prostatorectal fistula after intravesical bacillus calmetteguérin immunotherapy[J].Clin Endosc,2016,49(5):488-491.DOI:10.5946/ce.2015.145.
    [6]ELSHAL A M,ABDELHALIM A,BARAKAT T S,et al.Prostatic abscess:objective assessment of the treatment approach in the absence of guidelines[J].Arab J Urol,2014,12(4):262-268.DOI:10.1016/j.aju.2014.09.002.
    [7]TIWARI P,PAL D K,TRIPATHI A,et al.Prostatic abscess:diagnosis and management in the modern antibiotic era[J].Saudi J Kidney Dis Transpl,2011,22(2):298-301.
    [8]LEE C H,KU J Y,PARK Y J,et al.Evaluation of holmium laser for transurethral deroofing of severe and multiloculated prostatic abscesses[J].Korean J Urol,2015,56(2):150-156.DOI:10.4111/kju.2015.56.2.150.
    [9]PURKAIT B,KUMAR M,SOKHAL A K,et al.Outcome analysis of transrectal ultrasonography guided aspiration versus transurethral resection of prostatic abscess:10 years'experience from a tertiary care hospital[J].Arab J Urol,2017,15(3):254-259.DOI:10.1016/j.aju.2017.05.001.
    [10]EL-SHAZLY M,EL-ENZY N,EL-ENZY K,et al.Transurethral drainage of prostatic abscess:points of technique[J].Nephrourol Mon,2012,4(2):458-461.DOI:10.5812/numonthly.3690.
    [11]NOGUCHI W,INOUE Y,FUKUSHIMA M.A case of prostatic abscess with malignant lymphoma involving the prostate[J].Case Rep Urol,2014,2014:965823.DOI:10.1155/2014/965823.
    [12]KUMAR S,KASHYAPI B D,BAPAT S S.A rare presentation of tuberculous prostatic abscess in young patient[J].Int J Surg Case Rep,2015,10:80-82.DOI:10.1016/j.ijscr.2015.03.028.
    [13]KIM J H,YANG W J,KIM T H.Klebsiella pneumonia-induced prostate abscess:how to work it up?[J].Can Urol Assoc J,2014,8(11/12):E841-844.DOI:10.5489/cuaj.2155.
    [14]DUBOS M,BARRAUD O,FEDOU A L,et al.Prostatic abscesses and severe sepsis due to methicillin-susceptible staphylococcus aureus producing panton-valentine leukocidin[J].BMC Infect Dis,2014,14:466.DOI:10.1186/1471-2334-14-466.
    [15]ZHENG X,WANG X,ZHOU J,et al.Diagnosis and treatment of community-associated methicillin-resistant staphylococcus aureus prostatic abscess involving the seminal vesicle:a case report[J].Exp Ther Med,2015,9(3):835-838.DOI:10.3892/etm.2014.2147.
    [16]FLORES D M,MURRAY K S,GRIEBLING T L,et al.Transrectal ultrasound guided needle aspiration of a prostatic abscess:salvage treatment after failed transurethral resection[J].Urol Case Rep,2015,3(4):101-102.DOI:10.1016/j.eucr.2015.03.006.
    [17]JANA T,MACHICADO J D,DAVOGUSTTO G E,et al.Methicillin-resistant staphylococcus aureus prostatic abscess in a liver transplant recipient[J].Case Rep Transplant,2014,2014:854824.DOI:10.1155/2014/854824.
    [18]ELWAGDY S,ABDELKHALEK M,EL-KHESHEN A,et al.Role of transrectal sectional sonography(TRSS)in management of prostatic abscesses[J].Urol Ann,2015,7(3):334-338.DOI:10.4103/0974-7796.158505.
    [19]KINDO A J,RAMALAKSHMI S,GIRI S,et al.A fatal case of prostatic abscess in a post-renal transplant recipient caused by cladophialophora carrionii[J].Saudi J Kidney Dis Transpl,2013,24(1):76-79.
    [20]PORFYRIS O,KALOMOIRIS P.Prostatic abscess:case report and review of the literature[J].Arch Ital Urol Androl,2013,85(3):154-156.DOI:10.4081/aiua.2013.3.154.
    [21]LIAO C Y,YANG Y S,YEH Y C,et al.Invasive liver abscess syndrome predisposed by klebsiella pneumoniae related prostate abscess in a nondiabetic patient:a case report[J].BMC Res Notes,2016,9:395.DOI:10.1186/s13104-016-2188-y.
    [22]DESHPANDE A,HALEBLIAN G,RAPOSE A.Prostate abscess:MRSA spreading its influence into Gram-negative territory:case report and literature review[J].BMJ Case Rep,2013,2013:bcr2013009057.DOI:10.1136/bcr-2013-009057.
    [23]HSU L N,CHIANG P H,KANG C H.Emphysematous prostatic abscess:rare case and systematic review[J].J Formos Med Assoc,2015,114(3):292-293.DOI:10.1016/j.jfma.2013.07.002.
    [24]STAFFORD P,PRYBYS K M.Pyocystis and prostate abscess in a hemodialysis patient in the emergency department[J].West J Emerg Med,2014,15(6):655-658.DOI:10.5811/westjem.2014.5.22317.
    [25]DATTILO W R,SHIBER J.Prostatitis or prostatic abscess[J].J Emerg Med,2013,44(1):e121-122.DOI:10.1016/j.jemermed.2012.02.031.
    [26]DELL'ATTI L.Prostatic abscess after transrectal ultrasound-guided prostate biopsy.Case report[J].G Chir,2013,34(9/10):260-262.
    [27]JOHNSON M G,CAPLAN-SHAW C E,MCMACKEN M.Tuberculous prostate abscesses in an immunocompetent patient:a dramatic presentation of disseminated tuberculosis[J].Germs,2014,4(2):41-45.DOI:10.11599/germs.2014.1054.
    [28]MCALLISTER S C,BENERI C.Prostate abscess in an adolescent with AIDS[J].Glob Pediatr Health,2015,2:2333794X15582260.DOI:10.1177/2333794X15582260.
    [29]NABOUSH A,ABOU YASSINE A,YASMIN M,et al.Community-acquired methicillin-resistant staphylococcus aureus prostatic abscess presenting as acute urinary retention:a case report and review of the literature[J].Case Rep Infect Dis,2013,2013:761793.DOI:10.1155/2013/761793.
    [30]FABIANI A,FILOSA A,MAURELLI V,et al.Diagnostic and therapeutic utility of transrectal ultrasound in urological office prostatic abscess management:a short report from a single urologic center[J].Arch Ital Urol Androl,2014,86(4):344-348.DOI:10.4081/aiua.2014.4.344.
    [31]LACHANT D J,APOSTOLAKOS M,PIETROPAOLIA.Methicillin resistant staphylococcus aureus prostatic abscess with bacteremia[J].Case Rep Infect Dis,2013,2013:613961.DOI:10.1155/2013/613961.
    [32]JONEJA U,SHORT W R,ROBERTS A L.Disseminated tuberculosis with prostatic abscesses in an immunocompromised patient--a case report and review of literature[J].IDCases,2016,5:15-20.DOI:10.1016/j.idcr.2016.06.002.
    [33]CAVALLI Z,ADER F,CHIDIAC C,et al.Asymptomatic prostatic tuberculous abscess in an immunocompetent 54-year-old man with peritoneal tuberculosis[J].BMJ Case Rep,2015,2015(5726):1296-1298.DOI:10.1136/bcr-2015-212342.
    [34]GOYAL N K,GOEL A,SANKHWAR S,et al.Transurethral resection of prostate abscess:is it different from conventional transurethral resection for benign prostatic hyperplasia?[J].ISRN Urol,2013,2013:109505.DOI:10.1155/2013/109505.
    [35]KADOYA Y,KENZAKA T.Prostatic abscess in a patient with ST-elevation myocardial infarction:a case report[J].BMCCardiovasc Disord,2016,16:48.DOI:10.1186/s12872-016-0228-0.
    [36]DOO S W,KIM J H,YANG W J,et al.A case of tuberculous prostatitis with abscess[J].World J Mens Health,2012,30(2):138-140.DOI:10.5534/wjmh.2012.30.2.138.
    [37]TOLOSA-ALVAREZ A B,ROMERO-REQUENA J M,MERCHAN-CUENDA M.Prostatic abscess:clinical case and a literature review[J].Semergen,2016,42(4):280-282.DOI:10.1016/j.semerg.2015.06.013.
    [38]ANSARI PIRSARAEI P,TABSH K,LENTZ J.Rare dysuria:prostatic abscess due to disseminated coccidioidomycosis[J].Urol Case Rep,2016,9:12-14.DOI:10.1016/j.eucr.2016.07.008.
    [39]WEN S C,JUAN Y S,WANG C J,et al.Emphysematous prostatic abscess:case series study and review[J].Int JInfect Dis,2012,16(5):e344-349.DOI:10.1016/j.ijid.2012.01.002.
    [40]AGOCHUKWU N Q,RASTINEHAD A R,RICHTER L A,et al.Prostatic abscess in a pediatric patient with chronic granulomatous disease:report of a unique case and review of the literature[J].J Pediatr Surg,2012,47(2):400-403.DOI:10.1016/j.jpedsurg.2011.11.003.
    [41]SCOREY H,DANIEL S.Nocardia farcinica bacteraemia presenting as a prostate abscess[J].IDCases,2016,5:24-26.DOI:10.1016/j.idcr.2016.06.001.
    [42]ZARZYCKI G,BAR K,DTUGOSZ M,et al.Minimally invasive treatment of prostatic abscess-percutaneous transvesical drainage[J].Cent European J Urol,2012,65(4):224-226.DOI:10.5173/ceju.2012.04.art10.
    [43]PARK S C,LEE J W,RIM J S.Prostatic abscess caused by community-acquired methicillin-resistant Staphylococcus aureus[J].Int J Uro,2011,18(7):536-538.DOI:10.1111/j.1442-2042.2011.02774.x.
    [44]SUSANíBAR NAPURíL F,SIMóN RODRíGUEZ C,LóPEZMARTíN L,et al.Prostatic abscess:diagnosis and treatment of an infrequent urological entity[J].Arch Esp Urol,2011,64(1):62-66.
    [45]FLANNERY M T,HUMPHREY D.Case report of a prostatic abscess with a review of the literature[J].Case Rep Med,2012,2012:430657.DOI:10.1155/2012/430657.
    [46]RUíZ PLAZAS X,ALONSO RODRíGUEZ D,FERNáNDEZBARRANCO L,et al.Rectoprostatic fistula:unusual presentation of a prostatic abscess[J].Arch Esp Urol,2011,64(1):59-61.
    [47]ROBERTS M J,PARAMBI A,BARRETT L,et al.Multifocal abscesses due to multiresistant escherichia coli after transrectal ultrasound-guided prostate biopsy[J].Med J Aust,2013,198(5):282-284.
    [48]LIU J W,LIN T C,CHANG Y T,et al.Prostatic abscess of klebsiella pneumonia complicating septic pulmonary emboli and meningitis:a case report and brief review[J].Asian Pac J Trop Med,2017,10(1):98-100.DOI:10.1016/j.apjtm.2016.11.014.
    [49]MERCHANT C,VILLANUEVA D D,LALANI I,et al.PBP-2 negative methicillin resistant staphylococcus schleiferi bacteremia from a prostate abscess:an unusual occurrence[J].Case Rep Infect Dis,2016,2016:8979656.DOI:10.1155/2016/8979656.
    [50]TAN G,LI J,CHEN L,et al.Prostatic melioidosis rarely reported in China:two cases report and literatures review[J].Int J Clin Exp Med,2015,8(11):21830-21832.
    [51]GILMORE P E,BAIRD A D,JAVLE P M.Prostate abscess:a rare complication of brachytherapy for prostate cancer[J].Ann R Coll Surg Engl,2009,91(4):W12-14.DOI:10.1308/147870809X400985.
    [52]VANDEVELDE A,STEPANOVIC B.On a boat:a case in australia of endophthalmitis and pyogenic liver,prostatic,and lung abscesses in a previously well patient due to klebsiella pneumoniae[J].Case Rep Infect Dis,2014,2014:137248.DOI:10.1155/2014/137248.
    [53]NG T H,HOW S H,AMRAN A R,et al.Melioidotic prostatic abscess in Pahang[J].Singapore Med J,2009,50(4):385-389.
    [54]RADERMECKER D,MICHAUX I,LOUAGIE Y,et al.Prostatic abscess associated with Bacteroides fragilis mediastinitis after heart surgery[J].Interact Cardiovasc Thorac Surg,2010,10(4):659-660.DOI:10.1510/icvts.2009.225102.
    [55]BASIRI A,JAVAHERFOROOSHZADEH A.Percutaneous drainage for treatment of prostate abscess[J].Urol J,2010,7(4):278-280.
    [56]GARG P K,HADKE N S.Prostato-ano-cutaneous fistula:unusual complication of prostatic abscess[J].ANZ J Surg,2008,78(11):1032-1033.DOI:10.1111/j.1445-2197.2008.04727.x.
    [57]HESSTVEDT L,WILHELMSEN M,MENGSHOEL A T,et al.Two Norwegian patients with melioidosis presenting with bacteraemia and splenic and prostatic abscesses[J].J Travel Med,2011,18(6):418-421.DOI:10.1111/j.1708-8305.2011.00550.x.
    [58]PURI R,JAIN P,SUD R,et al.EUS-guided drainage of an isolated primary tubercular prostatic abscess[J].Gastrointest Endosc,2010,71(2):425-428.DOI:10.1016/j.gie.2009.07.032.
    [59]NAOUAR S,ATI N,BRAIEK S,et al.Spontaneous rupture into the peritoneal cavity:unusual presentation of prostatic abscess[J].Int J Surg Case Rep,2017,32:73-75.DOI:10.1016/j.ijscr.2017.02.006.
    [60]JUAN Y S,HUANG C H,CHANG K,et al.Emphysematous prostatic abscess due to candidiasis:a case report[J].Kaohsiung J Med Sci,2008,24(2):99-102.DOI:10.1016/S1607-551X(08)70104-9.
    [61]SALEH A,KIBEIDA A,AMIN E,et al.Prostatic abscess after stapled hemorrhoidopexy caused by esbl extended spectrum beta lactamase producing klebsiella pneumoniae:an additional challenge to postoperative sepsis[J].Case Rep Surg,2017,2017:4154016.DOI:10.1155/2017/4154016.
    [62]LEE P,ONG T,DAYANGKU NORLIDA A.Tuberculous prostatic abscess in an immunocompromised patient[J].Malays Fam Physician,2010,5(3):145-147.
    [63]CARROLL D E,MARR I,HUANG G K L,et al.Staphylococcus aureus prostatic abscess:a clinical case report and a review of the literature[J].BMC Infect Dis,2017,17(1):509.DOI:10.1186/s12879-017-2605-4.
    [64]DOCEKAL J,HALL J,REESE B,et al.A rare presentation of community acquired methicillin resistant staphylococcus aureus[J].Case Rep Infect Dis,2013,2013:543762.DOI:10.1155/2013/543762.
    [65]BHAVSAR M M,DEVARAJAN T V,NEMBI P S,et al.Metastatic endogenous endophthalmitis:a rare presentation with methicillin-resistant staphylococcus aureus prostatic abscess[J].Indian J Crit Care Med,2017,21(3):172-175.DOI:10.4103/ijccm.IJCCM_375_16.
    [66]GANDHI N M,LIN J,SCHAEFFER E.Nonspecific presentation of a multiloculated prostatic abscess after transurethral prostatic biopsy for elevated prostate-specific antigen level[J].Urol Case Rep,2014,2(6):194-196.DOI:10.1016/j.eucr.2014.08.005.
    [67]JIN K W,KIM E,KIM H,et al.Klebsiella endophthalmitis as reti na l vas cul i t i s with pro sta tic abs ces s[J].Optom Vis Sci,2015,92(7):e158-160.DOI:10.1097/OPX.0000000000000617.
    [68]EL HARRECH Y,CHAFIKI J,JANANE A,et al.US-guided transrectal drainage of prostatic abscesses[J].J Radiol,2010,91(2):227-229.
    [69]VERMA A,SINGH A,KISHORE K,et al.A rare presentation of disseminated tuberculosis:prostatic abscess[J].Indian J Tuberc,2017,64(4):330-333.DOI:10.1016/j.ijtb.2016.10.006.
    [70]ABREU D,ARROYO C,SUAREZ R,et al.Communityacquired methicillin resistant staphylococcus aureus:a new aetiological agent of prostatic abscess[J].BMJ Case Rep,2011.DOI:10.1136/bcr.10.2010.3463.
    [71]FOSTER C E,HULTEN K G,JANZEN N K,et al.Pediatric prostatic abscess caused by Methicillin-susceptible Staphylococcus aureus[J].Pediatr Infect Dis J,2017,36(4):426-427.DOI:10.1097/INF.0000000000001458.
    [72]MASON B M,HAKIMI A A,CLERKIN K J,et al.Successful percutaneous transperineal drainage of a large prostatic abscess[J].Urology,2010,76(6):1369-1370.DOI:10.1016/j.urology.2009.12.067.
    [73]VYAS J B,GANPULE S A,GANPULE A P,et al.Transrectal ultrasound-guided aspiration in the management of prostatic abscess:a single-center experience[J].Indian J Radiol Imaging,2013,23(3):253-257.DOI:10.4103/0971-3026.120262.
    [74]ARAVANTINOS E,KALOGERAS N,ZYGOULAKIS N,et al.Ultrasound-guided transrectal placement of a drainage tube as therapeutic management of patients with prostatic abscess[J].J E n d o u r o l,2 0 0 8,2 2(8):1 7 5 1-1 7 5 4.D O I:10.1089/end.2008.0265.
    [75]WU I,JONES J S.Intraprostatic abscess as a complication of salvage cryotherapy[J].Urology,2010,76(4):848.DOI:10.1016/j.urology.2009.09.063.
    [76]SHEAHAN G,VEGA VEGA A.Dramatic complications of prostatis:a prostatic abscess and scrotal abscess[J].ANZ JSurg,2013,83(11):889-890.DOI:10.1111/ans.12221.
    [77]GOYAL N K,GOEL A,SANKHWAR S,et al.Transurethral resection of prostate abscess:is it different from conventional transurethral resection for benign prostatic hyperplasia?[J].ISRN Urol,2013,2013:109505.
    [78]LIANG K,GUO W.Prostatic abscess caused by Mycobacterium tuberculosis and Escherichia coli in a patient with acquired immunodeficiency syndrome[J].Am J Med Sci,2015,350(2):153-154.DOI:10.1155/2013/109505.
    [79]KRISHNAMOHAN P,SCHANINGER T,BADDOUR L M,et al.Community-acquired methicillin-resistant Staphylococcus aureus prostatic abscesses[J].Am J Med Sci,2013,346(4):341-344.DOI:10.1097/MAJ.0b013e318294f53a.
    [80]VITHIYA G,RAJENDRAN T,MARIAPPAN,et al.Tubercular prostate abscess in an immunocompetent patient[J].Indian J Tuberc,2015,62(2):110-113.DOI:10.1016/j.ijtb.2015.04.011.
    [81]COLLINS S M,CORREA H,ORTENBERG J.Prostatic abscess in the newborn:an unrecognized source of urosepsis[J].Urology,2001,57(3):554.
    [82]LEE D S,CHOE H S,KIM H Y,et al.Acute bacterial prostatitis and abscess formation[J].BMC Urol,2016,16(1):38.DOI:10.1186/s12894-016-0153-7.
    [83]TRAPNELL J,ROBERTS M.Prostatic abscess[J].Br J Surg,1970,57(8):565-569.
    [84]WIERSINGA W J,VAN DER POLL T,WHITE N J,et al.Melioidosis:insights into the pathogenicity of Burkholderia pseudomallei[J].Nat Rev Microbiol,2006,4(4):272-282.DOI:10.1038/nrmicro1385.
    [85]那彦群,叶章群,孙颖浩,等.中国泌尿外科疾病诊断治疗指南手册[M].北京:人民卫生出版社,2014:442.

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