多西环素与保妇康栓联合治疗宫颈支原体感染的临床疗效观察
|
摘要
目的探讨多西环素联合保妇康栓在宫颈支原体感染患者中的临床治疗效果。方法选取2015年4月—2016年4月收治的80例宫颈支原体感染患者,采用随机对照方法分为对照组和实验组,对照组采用多西环素治疗,实验组在对照组基础上联合保妇康栓治疗,比较两组疗效。结果实验组治疗总有效率为95%,显著高于对照组(85%)(P<0.05);实验组治疗后复发率为5%,显著低于对照组(17.5%)(P<0.05);实验组宫颈管外口黏膜充血消失时间、糜烂创面恢复时间以及平均住院时间显著短于对照组(P<0.05);实验组用药后不良反应发生率为7.5%,显著低于对照组的17.5%(P<0.05)。结论宫颈支原体感染患者在多西环素治疗基础上联合保妇康栓治疗效果理想,能够提高临床疗效,降低复发率,且药物不良反应发生率低,值得推广应用。
Objective To study the the clinical treatment effect of doxycycline joint baofukang suppository in patients with cervical mycoplasma infection. Methods From April 2015 to April 2016 hospital diagnosis and treatment of 80 patients with cervical mycoplasma infection data analysis,using randomized controlled method divided the patients into control group and experimental group,control group treated with doxycycline,the experimental group on the basis of the control group was given baofukang suppository treatment,compared curative effect of two groups. Results Treatment group total effective rate was 95%,significantly higher than that of the control group(85%)(P < 0. 05); Experimental group after treatment the recurrence rate was 5%,significantly lower than that of the control group(17. 5%)(P <0. 05); Experimental cervical tube mouth mucosal hyperemia disappear time,erosion wound recovery time and the average hospitalization time,significantly shorter than that of the control group(P < 0. 05); The experimental group after 3cases of adverse drug reactions,the incidence of adverse reactions was 7. 5%,significantly lower than that of the control group(7 cases with adverse reactions,the incidence of adverse reactions was 17. 5%)(P < 0. 05). Conclusion The patients with cervical mycoplasma infection on the basis of doxycycline treatment combined baofukang treating effect is ideal,can improve the clinical curative effect,reduce recurrence rate,and low incidence of adverse drug reactions,is worthy of popularization and application.
Objective To study the the clinical treatment effect of doxycycline joint baofukang suppository in patients with cervical mycoplasma infection. Methods From April 2015 to April 2016 hospital diagnosis and treatment of 80 patients with cervical mycoplasma infection data analysis,using randomized controlled method divided the patients into control group and experimental group,control group treated with doxycycline,the experimental group on the basis of the control group was given baofukang suppository treatment,compared curative effect of two groups. Results Treatment group total effective rate was 95%,significantly higher than that of the control group(85%)(P < 0. 05); Experimental group after treatment the recurrence rate was 5%,significantly lower than that of the control group(17. 5%)(P <0. 05); Experimental cervical tube mouth mucosal hyperemia disappear time,erosion wound recovery time and the average hospitalization time,significantly shorter than that of the control group(P < 0. 05); The experimental group after 3cases of adverse drug reactions,the incidence of adverse reactions was 7. 5%,significantly lower than that of the control group(7 cases with adverse reactions,the incidence of adverse reactions was 17. 5%)(P < 0. 05). Conclusion The patients with cervical mycoplasma infection on the basis of doxycycline treatment combined baofukang treating effect is ideal,can improve the clinical curative effect,reduce recurrence rate,and low incidence of adverse drug reactions,is worthy of popularization and application.
引文
[1]郑少冰.联合应用壳聚糖宫颈抗菌膜和多西环素治疗非淋菌性宫颈炎的疗效观察[J].深圳中西医结合杂志,2014,24(4):107-108.
[2]黄平洁.LEEP刀联合保妇康栓治疗慢性宫颈炎98例疗效观察[J].临床合理用药杂志,2011,1(5):244.
[3]黄新可,张羡,罗新,等.女性下生殖道沙眼衣原体及解脲支原体感染与输卵管妊娠的相关性[J].中国实用妇科与产科杂志,2012,28(8):628-630.
[4]王勇,祝晓莹,袁红瑛,等.生殖道支原体和衣原体感染对生育的影响及对18种抗菌药的耐药性[J].中国临床药理学杂志,2013,29(6):460-462.
[5]殷秀荣,李丽玮.不孕与生殖道支原体沙眼衣原体感染及药敏分析[J].中国妇幼保健,2010,25(8):1120-1121.
[6]潘华,曹晓玲,彭玉兰,等.多西环素与克拉霉素在治疗生殖道支原体感染的对比临床研究[J].北方药学,2016,13(9):62-63.
[7]覃健,陈道意.保妇康栓联合阿奇霉素对支原体宫颈炎的疗效分析[J].中国医学创新,2012,9(17):40-41.
[2]黄平洁.LEEP刀联合保妇康栓治疗慢性宫颈炎98例疗效观察[J].临床合理用药杂志,2011,1(5):244.
[3]黄新可,张羡,罗新,等.女性下生殖道沙眼衣原体及解脲支原体感染与输卵管妊娠的相关性[J].中国实用妇科与产科杂志,2012,28(8):628-630.
[4]王勇,祝晓莹,袁红瑛,等.生殖道支原体和衣原体感染对生育的影响及对18种抗菌药的耐药性[J].中国临床药理学杂志,2013,29(6):460-462.
[5]殷秀荣,李丽玮.不孕与生殖道支原体沙眼衣原体感染及药敏分析[J].中国妇幼保健,2010,25(8):1120-1121.
[6]潘华,曹晓玲,彭玉兰,等.多西环素与克拉霉素在治疗生殖道支原体感染的对比临床研究[J].北方药学,2016,13(9):62-63.
[7]覃健,陈道意.保妇康栓联合阿奇霉素对支原体宫颈炎的疗效分析[J].中国医学创新,2012,9(17):40-41.