对比MS BLOCK T1rho、MS HS8 T1rho及3D BLOCK T1rho序列肝脏MR图像质量及T1rho值
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摘要
目的对比分析MS BLOCK T1rho、MS HS8 T1rho及3D BLOCK T1rho序列肝脏MR图像质量及T1rho值。方法分别采用MS BLOCK T1rho(n=33)、MS HS8 T1rho(n=34)及3D BLOCK T1rho(n=22)序列对40名成年健康志愿者行腹部MR扫描,比较3种序列肝脏图像质量及T1rho值,以Pearson相关分析观察3种序列T1rho值的相关性。结果 3种序列的图像质量评分及T1rho值差异均有统计学意义(P均<0.01),其中MS HS8 T1rho图像质量评分及T1rho值均高于其他2种序列(P均<0.05)。MS BLOCK T1rho序列图像的T1rho值与MS HS8 T1rho、3D BLOCK T1rho均呈正相关(r=0.59、0.73,P均<0.05),MS HS8 T1rho的T1rho值与3D BLOCK T1rho呈正相关(r=0.72,P<0.05)。结论 MS BLOCK T1rho、MS HS8 T1rho及3D BLOCK T1rho序列均可应用于健康人肝脏MR成像,但用于诊断肝脏疾病时需设定不同的参考值范围。
Objective To compare image quality and T1rho value of liver MRI using MS BLOCK T1rho, MS HS8 T1rho and 3 D BLOCK T1rho sequences. Methods Totally 40 healthy volunteers were enrolled. MR scanning was performed using MS BLOCK T1rho(n=33), MS HS8 T1rho(n=34) and 3D BLOCK T1rho(n=22) sequences. The image quality and T1rho value were compared among these sequences. The correlation of T1rho value among three sequences were evaluated with Pearson correlation analysis. Results Statistical differences were found in image quality and T1rho value among three sequences(both P<0.01). The image quality and T1rho value of MS HS8 T1rho sequence were higher than those of the other two sequences(all P<0.05). T1rho value of MS BLOCK T1rho was positively correlated with MS HS8 T1rho and 3D BLOCK T1rho(r=0.59, 0.73, both P<0.05), and MS HS8 T1rho was positively correlated with 3D BLOCK T1rho(r=0.72, P<0.05). Conclusion MS BLOCK T1rho, MS HS8 T1rho and 3D BLOCK T1rho sequences can be used in MR imaging in healthy human. However, different references ranges should be set for diagnosis of liver diseases.
Objective To compare image quality and T1rho value of liver MRI using MS BLOCK T1rho, MS HS8 T1rho and 3 D BLOCK T1rho sequences. Methods Totally 40 healthy volunteers were enrolled. MR scanning was performed using MS BLOCK T1rho(n=33), MS HS8 T1rho(n=34) and 3D BLOCK T1rho(n=22) sequences. The image quality and T1rho value were compared among these sequences. The correlation of T1rho value among three sequences were evaluated with Pearson correlation analysis. Results Statistical differences were found in image quality and T1rho value among three sequences(both P<0.01). The image quality and T1rho value of MS HS8 T1rho sequence were higher than those of the other two sequences(all P<0.05). T1rho value of MS BLOCK T1rho was positively correlated with MS HS8 T1rho and 3D BLOCK T1rho(r=0.59, 0.73, both P<0.05), and MS HS8 T1rho was positively correlated with 3D BLOCK T1rho(r=0.72, P<0.05). Conclusion MS BLOCK T1rho, MS HS8 T1rho and 3D BLOCK T1rho sequences can be used in MR imaging in healthy human. However, different references ranges should be set for diagnosis of liver diseases.
引文
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[2] Deng M,Zhao F,Yuan J,et al.Liver T1rho MRI measurement in healthy human subjects at 3 T:A preliminary study with a two-dimensional fast-field echo sequence.Brit J Radiol,2012,85(1017):e590-e595.
[3] Allkemper T,Sagmeister F,Cicinnati V,et al.Evaluation of fibrotic liver disease with whole-liver T1rho MR imaging:A feasibility study at 1.5 T.Radiology,2014,271(2):408-415.
[4] 孟祥虹,王植,万业达.T1ρ的基本原理及临床应用新进展.中国医学影像技术,2015,31(4):626-630.
[5] Wang YX,Yuan J,Chu ES,et al.T1rho MR imaging is sensitive to evaluate liver fibrosis:An experimental study in a rat biliary duct ligation model.Radiology,2011,259(3):712-719.
[6] Zhao F,Wang YX,Yuan J,et al.MR T1rho as an imaging biomarker for monitoring liver injury progression and regression:An experimental study in rats with carbon tetrachloride intoxication.Eur Radiol,2012,22(8):1709-1716.
[7] Hu G,Zhang X,Liang W,et al.Assessment of liver fibrosis in rats by MRI with apparent diffusion coefficient and T1 relaxation time in the rotating frame.J Magn Reson Imaging,2016,43(5):1082-1089.
[8] Zhang H,Yang Q,Yu T,et al.Comparison of T2,T1rho,and diffusion metrics in assessment of liver fibrosis in rats.J Magn Reson Imaging,2017,45(3):741-750.
[9] Rauscher I,Eiber M,Ganter C,et al.Evaluation of T1rho as a potential MR biomarker for liver cirrhosis:Comparison of healthy control subjects and patients with liver cirrhosis.Eur J Radiol,2014,83(6):900-904.