加减安魂汤治疗血虚痰阻型慢性失眠
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摘要
目的观察加减安魂汤对心血亏虚、痰饮内阻型慢性失眠患者的睡眠质量和临床症状的改善情况。方法将120例心血亏虚、痰饮内阻型慢性失眠患者随机分为治疗组(60例)和对照组(60例)。治疗组采用加减安魂汤(龙眼肉,半夏,当归,茯苓,生龙牡)口服治疗,对照组采用百乐眠胶囊口服治疗,疗程均为2周。治疗前后均采用匹茨堡睡眠质量指数量表(PSQI)和中医证候积分量表进行评分。结果治疗后治疗组和对照组的PSQI评分分别为(6.23±2.11)和(8.23±2.50),2组比较差异有统计学意义(P<0.05);治疗后治疗组和对照组的中医证候积分分别为(18.75±10.95)和(22.75±11.12),2组比较差异有统计学意义(P<0.05);2组临床有效率比较差异有统计学意义(P<0.05)。结论考虑到加减安魂汤可明显改善心血亏虚、痰饮内阻型慢性失眠患者的睡眠质量及临床症状,心血亏虚合并痰饮内阻可能为此类疾病的基本病机。
Objective To investigate the efficacy of the Anhun decoction on blood efficiency and retention of phlegm and fluid resistance chronic insomnia patients.Methods 120 blood efficiency and retention of phlegm and fluid resistance chronic insomnia patients were randomly divided into the trial group(60) and the control group(60),the trial group was treated by Anhun decoction while the control group by Bailemian capsule.The course of the treatment were both 2 weeks.Before and after treatment both group filled out Pittsburg Sleep Quality Index(PSQI) and TCM syndrome scale.Results After treatment the values of PSQI were(6.23±2.11) and(8.23±2.50)(P<0.05) in the trial group and control group respectively,and the values of TCM syndrome were(18.75±10.95) and(22.75±11.12)(P<0.05).The clinical effective rate of the two groups was statistically significant(P<0.05).Conclusion Anhun decoction can remarkably improve the sleep quality and symptoms of blood efficiency and retention of phlegm and fluid resistance insomnia patients.Blood efficiency combined with phlegm obstruction may be the basic pathogenesis of this disease.
Objective To investigate the efficacy of the Anhun decoction on blood efficiency and retention of phlegm and fluid resistance chronic insomnia patients.Methods 120 blood efficiency and retention of phlegm and fluid resistance chronic insomnia patients were randomly divided into the trial group(60) and the control group(60),the trial group was treated by Anhun decoction while the control group by Bailemian capsule.The course of the treatment were both 2 weeks.Before and after treatment both group filled out Pittsburg Sleep Quality Index(PSQI) and TCM syndrome scale.Results After treatment the values of PSQI were(6.23±2.11) and(8.23±2.50)(P<0.05) in the trial group and control group respectively,and the values of TCM syndrome were(18.75±10.95) and(22.75±11.12)(P<0.05).The clinical effective rate of the two groups was statistically significant(P<0.05).Conclusion Anhun decoction can remarkably improve the sleep quality and symptoms of blood efficiency and retention of phlegm and fluid resistance insomnia patients.Blood efficiency combined with phlegm obstruction may be the basic pathogenesis of this disease.
引文
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[18]贾秋颖.中医药治疗老年性失眠24例疗效观察[J].长春中医药大学学报,2009,25(6):871.
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[2]李艳,徐碧云,肖芳,等.加味逍遥散对心理应激性失眠患者睡眠的影响[J].中国中西医结合杂志,2009,29(3):208-211.
[3]中华医学会精神病学分会.中国精神障碍分类与诊断标准[J].中国精神科杂志,2001,34(3):184-188.
[4]郑筱萸.中药新药临床研究指导原则[M].北京:中国医药科技出版社,2002:380-383.
[5]王平,孔明望.疏肝解郁论治失眠[J].湖北中医杂志,2001,23(10):17-18.
[6]张万廷,杨宏宇.天王补心丹加味治疗阴血亏虚型失眠66例[J].河南中医学院学报,2006,21(2):57.
[7]李景.失眠证从脾胃论治[J].中国中医基础医学杂志,2002,8(1):28.
[8]叶人,袁拯忠,何金彩,等.补肾填精法治疗老年失眠症的临床观察[J].中医药学刊,2006,24(10):1923-1924.
[9]蔡向红,陈利国.不寐从火论治的机理[J].中国中医基础医学杂志,1997,3(4):15-17.
[10]李建辉.顽固性不寐可从痰论治[J].甘肃中医,2000,13(12):17-18.
[11]赵学勤.自拟清痰安魂汤治疗胆热郁滞型不寐证200例[J].北京中医,2005,24(4):227.
[12]舒进田,石建太.活血化瘀法治疗不寐小议[J].陕西中医,2009,30(4):511.
[13]马学玉.不寐从瘀论治体会[J].陕西中医,2001,22(2):127.
[14]尚世龙,李志平,王中男.加味交泰汤治疗心肾不交型失眠30例[J].长春中医药大学学报,2013,29(6):1054-1055.
[15]刘鹏,韩永和.健脾安神推拿法治疗心脾两虚失眠30例[J].吉林中医药,2007,27(6):43.
[16]韦婉.温胆汤加减治疗痰瘀阻滞型更年期失眠[J].吉林中医药,2013,33(7):675-677.
[17]丁维超.针刺神门、三阴交穴为主治疗失眠84例[J].吉林中医药,2016,36(10):46.
[18]贾秋颖.中医药治疗老年性失眠24例疗效观察[J].长春中医药大学学报,2009,25(6):871.
[19]张锡纯.屡试屡效方[M].北京:学苑出版社,2007:46.