地黄连属植物的化学成分及生物活性研究进展
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摘要
地黄连属植物在我国民间用药较多,因富含柠檬苦素类成分而受到广泛关注。柠檬苦素类衍生物具有抗肿瘤、抗炎、抗菌、抗烟草花叶病毒、昆虫拒食等药理活性。对地黄连属植物化学成分和生物活性的研究进展进行综述,以期为该属植物的进一步研究和开发利用提供参考。
Munronia Wight has been widely used in folk of China. Due to the rich content of limonoid, this genus has always been a hot research topic. So, many researches on phytochemistry and pharmacology of this genus have been carried out over the past 20 years. In this paper, the systematic classification, chemical constituents, and pharmacological effects of plants from Munronia Wight have been summarized. It may provide the reference for the further studies of this genus.
Munronia Wight has been widely used in folk of China. Due to the rich content of limonoid, this genus has always been a hot research topic. So, many researches on phytochemistry and pharmacology of this genus have been carried out over the past 20 years. In this paper, the systematic classification, chemical constituents, and pharmacological effects of plants from Munronia Wight have been summarized. It may provide the reference for the further studies of this genus.
引文
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[16]Qi S H,Chen L,Wu D G,et al.Novel tetranortriterpenoid derivatives from Munronia henryi[J].Tetrahedron,2003,59(23):4193-4199.
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[22]章华平.一、两种杜鹃花科植物——云南金叶子和大白花杜鹃化学成分研究二、楝科植物云南地黄连化学成分研究[D].上海:中国科学院上海药物研究所,2004.
[23]韦健全,罗莹,黄健,等.地黄连提取物镇痛抗炎作用及急性毒性[J].中国实验方剂学杂志,2011,17(16):160-163.
[24]黎柳锋,曾涛,韦德卫,等.10种植物提取物对小菜蛾产卵忌避作用研究初报[J].南方农业学报,2011,42(2):155-157.
[25]韦德卫,黎柳锋,曾宪儒,等.21种植物提取物对荔枝蒂蛀虫产卵的影响[J].西南农业学报,2012,25(1):153-156.
[2]Zhang R J,Chen H F,Xing F W,et al.Munronia yinggelingensis sp.nov.(Meliaceae)from Hainan,China[J].Nord J Bot,2009,27(5):376-378.
[3]国家中医药管理局《中华本草》编委会.中华本草(第13卷)[M].上海:上海科学技术出版社,1999.
[4]马雯芳,唐玉荣,颜萍花,等.壮药矮陀陀中总生物碱含量测定条件优选及不同产地药材含量比较[J].中国药房,2016,27(4):476-478.
[5]Tan Q G,Luo X D.Meliaceous limonoids:chemistry and biological activities[J].Chem Rev,2011,111(11):7437-7522.
[6]Yan Y,Zhang J,Huang T,et al.Bioactive limonoid constituents of Munronia henryi[J].J Nat Prod,2015,78(4):811-821.
[7]Ge Y H,Zhang J X,Mu S Z,et al.Munronoids A-J,ten new limonoids from Munronia unifoliolata Oliv.[J].Tetrahedron,2012,68(2):566-572.
[8]Li X L,He Q X,Zhang F L,et al.Chemical constituents from Munronia sinica and their bioactivities[J].Nat ProdBioprospect,2012,2(2):76-80.
[9]Zhang H P,Bao G H,Wang H B,et al.Two new limonoids from Munronia henryi[J].Nat Prod Res,2004,18(5):415-418.
[10]Cai X H,Luo X D.A new tetranortriterpenoid from Munronia delavayi[J].Chin J Chem,2007,25(7):986-988.
[11]Ge Y H,Liu K X,Zhang J X,et al.The limonoids and their antitobacco mosaic virus(TMV)activities from Munronia unifoliolata Oliv.[J].J Agric Food Chem,2012,60(17):4289-4295.
[12]Lin B D,Chen H D,Liu J,et al.Mulavanins A-E:limonoids from Munronia delavayi[J].Phytochemistry,2010,71(13):1596-1601.
[13]Yan Y,Yuan C M,Di Y T,et al.Limonoids from Munronia henryi and their anti-tobacco mosaic virus activity[J].Fitoterapia,2015,107:29-35.
[14]蔡洁云.山楝的化学成分及其化学防御活性研究[D].北京:中国科学院大学,2013.
[15]Qi S H,Wu D G,Chen L,et al.Insect antifeedants from Munronia henryi:structure of munroniamide[J].J Agric Food Chem,2003,51(24):6949-6952.
[16]Qi S H,Chen L,Wu D G,et al.Novel tetranortriterpenoid derivatives from Munronia henryi[J].Tetrahedron,2003,59(23):4193-4199.
[17]Cai X H,Du Z Z,Luo X D.Tirucallane triterpenoid saponins from Munronia delavayi Franch[J].Helv ChimActa,2007,90(10):1980-1986.
[18]郭志永,黎平,陈萍,等.民族药用植物矮陀陀的化学成分研究[J].中央民族大学学报:自然科学版,2014,23(4):57-59.
[19]Cai X H,Luo X D,Zhou J,et al.A new pregnane from Munronia delavayi Franch(Meliaceae)[J].J Integr PlantBiol,2006,48(9):1126-1128.
[20]漆淑华.七种药用植物的化学成分研究[D].昆明:中国科学院昆明植物研究所,2003.
[21]Qi S H,Wu D G,Ma Y B,et al.The chemical constituents of Munronia henryi[J].J Asian Nat Prod Res,2003,5(3):215-221.
[22]章华平.一、两种杜鹃花科植物——云南金叶子和大白花杜鹃化学成分研究二、楝科植物云南地黄连化学成分研究[D].上海:中国科学院上海药物研究所,2004.
[23]韦健全,罗莹,黄健,等.地黄连提取物镇痛抗炎作用及急性毒性[J].中国实验方剂学杂志,2011,17(16):160-163.
[24]黎柳锋,曾涛,韦德卫,等.10种植物提取物对小菜蛾产卵忌避作用研究初报[J].南方农业学报,2011,42(2):155-157.
[25]韦德卫,黎柳锋,曾宪儒,等.21种植物提取物对荔枝蒂蛀虫产卵的影响[J].西南农业学报,2012,25(1):153-156.