山楝中杀虫活性化学成分的提取与研究
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摘要
从山楝枝叶中分离得到5个化合物,包括4个倍半萜类化合物及1个甾体化合物,经波谱解析分别鉴定为15-羟基-α-杜松醇(1),1S,4S,5S,10R-4,10-愈创木烷二醇(2),4(15)-桉叶烯-1β,6β-二醇(3),4(15)-桉叶烯-1β,6α-二醇(4),3α,16β,20,22-四羟基麦角甾-5,24(28)-二烯(5).其中,化合物1、2为首次从山楝属植物中分离得到.杀虫活性测试结果表明,化合物2、3、4对卤虫(Artemiasalina)具有良好的抑制活性,提示该类化合物在杀虫领域具有潜在的应用价值.
In this research,five natural compounds including four sesquiterpenoids and one steride are isolated from the twigs and leaves of Aphanamixis polystachya( Wall.) R. N. Parker. Their insecticidal activities are evaluated,and compounds 2,3 and 4 exhibit a good inhibitory activity on Artemiasalina that implies their potential application as an insecticide.
In this research,five natural compounds including four sesquiterpenoids and one steride are isolated from the twigs and leaves of Aphanamixis polystachya( Wall.) R. N. Parker. Their insecticidal activities are evaluated,and compounds 2,3 and 4 exhibit a good inhibitory activity on Artemiasalina that implies their potential application as an insecticide.
引文
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[9] ZHANG G W,MA X Q,SU J Y,et al. Two new bioactive sesquiterpenes from the soft coral Sinulariasp[J]. Nat Prod Res,2006,20(7):659-664.
[10] SUN Z,CHEN B,ZHANG S,et al. Four new eudesmanes from Caragana intermedia and their biological activities[J]. J Nat Prod,2004,67(12):1975-1979.
[11] KAMEL A. 7-epi-Eudesmanes from Teucrium polium[J]. J Nat Prod,1995,58(3):428-431.
[12] ZHANG H J,TAN G T,SANTARSIERO B D,et al. New sesquiterpenes from Litsea verticillata[J]. J Nat Prod,2003,66(5):609-615.
[13] TAN Q G,LI X N,CHEN H,et al. Sterols and terpenoids from Melia azedarach[J]. J Nat Prod,2010,73(4):693-697.
[2] CHEN S K,LI H,CHEN P Y. Flora of China[M]. Beijing:Science Press,1997.
[3] CHANDRASEKHARAN S,CHAKRABORTTY T. Aphanamixol,a diterpene alcohol from Aphanamixis polystachya(wall)parker[J]. J Indian Chem Soc,1968,45(3):208-212.
[4] GUPTA M,LASKAR S. Surface hydrocarbons from the leaves of Amoora rohituka W&A[J]. Biosci,Biotechnol Res Asia,2009,6(1):379-381.
[5] DAULATABAD C D,JAMKHANDI A M. A keto fatty acid from Amoora rohituka seed oil[J]. Phytochemistry,1997,46(1):155-156.
[6] JAIN S A,SRIVASTAVA S K. 8-C-Methyl-quercetin-3-O-β-D-xylopyranoside,a new flavone glycoside from the roots of Amoora rohituka[J]. J Nat Prod,1985,48(2):299-301.
[7] CHATTERJEE A,KUNDU A B. Isolation,structure,and stereochemistry of aphanamixin-a new triterpene from Aphanamixis polystachya wall and parker[J]. Tetrahedron Lett,1967,8(16):1471-1476.
[8] KUO Y H,CHEN C H,CHIEN S C,et al. Five new cadinane-type sesquiterpenes from the heartwood of Chamaecyparis obtusa var. formosana[J]. J Nat Prod,2002,65(1):25-28.
[9] ZHANG G W,MA X Q,SU J Y,et al. Two new bioactive sesquiterpenes from the soft coral Sinulariasp[J]. Nat Prod Res,2006,20(7):659-664.
[10] SUN Z,CHEN B,ZHANG S,et al. Four new eudesmanes from Caragana intermedia and their biological activities[J]. J Nat Prod,2004,67(12):1975-1979.
[11] KAMEL A. 7-epi-Eudesmanes from Teucrium polium[J]. J Nat Prod,1995,58(3):428-431.
[12] ZHANG H J,TAN G T,SANTARSIERO B D,et al. New sesquiterpenes from Litsea verticillata[J]. J Nat Prod,2003,66(5):609-615.
[13] TAN Q G,LI X N,CHEN H,et al. Sterols and terpenoids from Melia azedarach[J]. J Nat Prod,2010,73(4):693-697.