MRI与三维超声在产前胎儿畸形筛查中的应用
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摘要
目的 MRI与三维超声在产前胎儿畸形筛查中的应用。方法选择2016年1月到2018年1月到医院进行产检孕妇90例,所有孕妇均进行三维超声及MRI检测。比较三维超声及MRI检出效能,统计两种检测方式对不同部位畸形胎儿检出率,统计两种检测方式对不同类型畸形胎儿检出率。结果三维超声诊断胎儿畸形准确率86.67%、灵敏度89.16%、特异度57.14%,MRI诊断胎儿畸形准确率92.22%、灵敏度93.98%、特异度71.43%;随访结果显示共有131处畸形,MRI在颅面部、腹部处畸形、神经系统畸形、泌尿系统畸形检出率高于三维超声检测,差异有统计学意义(P<0.05)。结论 MRI在产前胎儿畸形筛查中检出率更高。
Objective To explore the application of MRI and three-dimensional ultrasound in the screening of prenatal fetal malformation. Methods A total of 90 cases of pregnant women who admitted to the hospital for production inspection from January 2016 to January 2018 were enrolled. All pregnant patients were given three-dimensional ultrasound and MRI. The detection efficiency of three-dimensional ultrasound and MRI were compared, and the detection rates of two detection methods for malformed fetuses in different parts were counted, and the detection rates of different types of malformed fetuses were counted. Results The accuracy rate, sensitivity and specificity in the diagnosis of fetal malformation were 86.67%, 89.16% and 57.14% by three-dimensional ultrasound,and were 92.22%, 93.98% and 71.43% by MRI. The follow-up results showed that there were 131 malformations, and the detection rates of MRI in craniofacial malformation and abdomen malformation were higher than those of three-dimensional ultrasound(P<0.05). The detection rates of MRI in the nervous system malformation and urinary system malformation were higher than those of three-dimensional ultrasound(P<0.05).Conclusion MRI has a high detection rate in prenatal fetal malformation screening.
Objective To explore the application of MRI and three-dimensional ultrasound in the screening of prenatal fetal malformation. Methods A total of 90 cases of pregnant women who admitted to the hospital for production inspection from January 2016 to January 2018 were enrolled. All pregnant patients were given three-dimensional ultrasound and MRI. The detection efficiency of three-dimensional ultrasound and MRI were compared, and the detection rates of two detection methods for malformed fetuses in different parts were counted, and the detection rates of different types of malformed fetuses were counted. Results The accuracy rate, sensitivity and specificity in the diagnosis of fetal malformation were 86.67%, 89.16% and 57.14% by three-dimensional ultrasound,and were 92.22%, 93.98% and 71.43% by MRI. The follow-up results showed that there were 131 malformations, and the detection rates of MRI in craniofacial malformation and abdomen malformation were higher than those of three-dimensional ultrasound(P<0.05). The detection rates of MRI in the nervous system malformation and urinary system malformation were higher than those of three-dimensional ultrasound(P<0.05).Conclusion MRI has a high detection rate in prenatal fetal malformation screening.
引文
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[11]龙璨,周启昌,曹丹鸣,等琪.应用三维超声测量正常胎儿与先天性心脏病胎儿全脑容积的研究[J].中国循证儿科杂志,2014,9(4):278-282.
[12]魏秋菊,蔡爱露,王晓光,等.产前三维超声诊断胎儿椎体形成障碍[J].中国超声医学杂志,2014,30(6):548-554.
[13]周怡,张超学,赵晟,等.三维超声表面成像技术在胎儿肢体畸形筛查中的相关研究[J].安徽医科大学学报,2014,49(12):1805-1807.
[14]李旭,胡克非,尹传高,等.MRI在诊断胎儿主动脉弓畸形中的价值[J].中华放射学杂志,2015(9):694-697.
[15]王云花.超声与MRI在产前诊断胎儿畸形中的价值[J].中国CT和MRI杂志,2018,16(4):125-127,142.
[2]徐嘉悦,牟雨婵,张菊英.四川省农村地区产前检查现状及影响因素分析[J].现代预防医学,2017,44(10):1803-1806.
[3]Hamdi A,Rebhi F,Achour A,et al.Prenatal diagnosis of fetal malformations in a maternity Level 3:about 100cases[J].Geburtshilfe Und Frauenheilkunde,2016,76(5):P50.
[4]Bernaschek G,Stuempflen I,Deutinger J.The influence of the experience of the investigator on the rate of sonographic diagnosis of fetal malformations in Vienna[J].Prenatal Diagnosis,2015,16(9):807-811.
[5]Platt L D,Barth R A,Pugash D.Current Controversies in Prenatal Diagnosis 3:Fetal MRI should be performed in all prenatally detected fetuses with a major structural abnormality[J].Prenatal Diagnosis,2018,38(3):166-172.
[6]张晓敏,郭小春.彩色多普勒超声在产前胎儿畸形筛查中的应用价值[J].中国现代医学杂志,2017,27(3):112-115.
[7]罗德清,陈欣林,朱霞,等.产前超声和MRI在诊断胎儿畸形中的应用[J].中国医学影像技术,2016,32(4):586-590.
[8]陈雨骤,沈理,顾娟,等.崇明地区产前系统超声筛查胎儿畸形8 1 3 0例临床分析[J].中国超声医学杂志,2016,32(1):46-48.
[9]张少丹,陈薇.MRI与常规超声诊断胎儿常见畸形的随机多中心对比分析[J].中国CT和MRI杂志,2015,13(9):113-115.
[10]赵白信.研究产前超声筛查对妊娠中期胎儿复杂性心脏畸形的诊断价值[J].罕少疾病杂志,2017,24(6):18-19.
[11]龙璨,周启昌,曹丹鸣,等琪.应用三维超声测量正常胎儿与先天性心脏病胎儿全脑容积的研究[J].中国循证儿科杂志,2014,9(4):278-282.
[12]魏秋菊,蔡爱露,王晓光,等.产前三维超声诊断胎儿椎体形成障碍[J].中国超声医学杂志,2014,30(6):548-554.
[13]周怡,张超学,赵晟,等.三维超声表面成像技术在胎儿肢体畸形筛查中的相关研究[J].安徽医科大学学报,2014,49(12):1805-1807.
[14]李旭,胡克非,尹传高,等.MRI在诊断胎儿主动脉弓畸形中的价值[J].中华放射学杂志,2015(9):694-697.
[15]王云花.超声与MRI在产前诊断胎儿畸形中的价值[J].中国CT和MRI杂志,2018,16(4):125-127,142.