超低位去大骨瓣术联合亚低温治疗重型颅脑损伤的临床疗效
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摘要
目的探讨超低位去大骨瓣术联合亚低温治疗重型颅脑损伤的临床疗效。方法选取2010年4月~2015年4月期间收治的重度颅脑损伤患者180例,随机分为试验组、对照组A组、对照B组,三组分别采取亚低温联合超低位去大骨瓣术、超低位去骨瓣减压及常规去骨瓣,观察三组疗效。结果术后,试验组第5、10 d时搏动指数(PI)、血乳酸(Jlac)均明显低于其他两组(P<0.05),颈内静脉血样饱和度(JSO2)明显高于对照B组(P<0.05),同时,术后试验组预后明显优于其他两组(P<0.05)。结论采取超低位去大骨瓣术联合亚低温治疗重度颅脑损伤,疗效显著,值得推广。
Objective To study the curative effect of mild hypothermia therapy combined with ultra-low large craniotomy in the severe craniocerebral injury. Methods 180 patients with severe craniocerebral injury treated from April 2010 to April 2015 in our hospital were selected and equally divided into test group, control group A and control group B. Three groups respectively adopted the ultra-low large craniotomy, ultra-low decompressive craniotomy and conventional method of removing bone valve. The curative effect of three groups was observed. Results After 5 d and 10 d of surgery, PI and Jlac of test group was significantly lower than that of the other two groups(P < 0.05); JSO2 of test group was higher than that of control group B(P < 0.05); after treatment,the prognosis of test group was significantly better than that of the other two groups(P < 0.05).Conclusion The mild hypothermia therapy combined with ultra-low large craniotomy has an obvious effect in the severe craniocerebral injury. It is worthy of promotion.
Objective To study the curative effect of mild hypothermia therapy combined with ultra-low large craniotomy in the severe craniocerebral injury. Methods 180 patients with severe craniocerebral injury treated from April 2010 to April 2015 in our hospital were selected and equally divided into test group, control group A and control group B. Three groups respectively adopted the ultra-low large craniotomy, ultra-low decompressive craniotomy and conventional method of removing bone valve. The curative effect of three groups was observed. Results After 5 d and 10 d of surgery, PI and Jlac of test group was significantly lower than that of the other two groups(P < 0.05); JSO2 of test group was higher than that of control group B(P < 0.05); after treatment,the prognosis of test group was significantly better than that of the other two groups(P < 0.05).Conclusion The mild hypothermia therapy combined with ultra-low large craniotomy has an obvious effect in the severe craniocerebral injury. It is worthy of promotion.
引文
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[2]宣宏飞,芦明,董伟峰,等.超低位去大骨瓣术联合亚低温治疗重型颅脑损伤的临床研究.浙江医学,2012,34(5):361-363.
[3]赵明,杜国森,王马军,等.超低位大骨瓣开颅治疗大面积脑梗死.中华神经外科杂志,2011,27(10):1033.
[4]郑德群,汪彤彤,岳培东,等.改良外伤超低位标准大骨瓣手术应用体会.安徽医药,2010,14(11):1330-1331.