血清肌红蛋白检验在急性心肌梗塞临床检验中的应用价值探析
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摘要
目的探究和分析血清肌红蛋白检验在急性心肌梗塞临床检验中的应用价值。方法方便选择该院自2014年1月—2015年12月收治的122例急性心肌梗塞患者作为研究对象(设为研究组),另选择同期在该院进行健康体检的122名受试人员作为参照对象(设为对照组),两组受试人员均行血清肌红蛋白检验,对比两组血清肌红蛋白、血清肌钙蛋白l水平,并在治疗后4 h、24 h、3 d时对研究组患者进行血清肌红蛋白复测,观察和对比其血清肌红蛋白、血清肌钙蛋白l水平变化情况。结果研究组患者血清肌红蛋白、血清肌钙蛋白l水平(189.6±44.5)μg/L、(0.067±0.008)μg/L均显著高于对照组(56.9±14.3)μg/L、(0.001 1±0.002)μg/L,两组对比差异有统计学意义(t=8.925,P<0.05,t=11.257,P<0.05);研究组患者治疗后4 h时,血清肌红蛋白、血清肌钙蛋白l水平明显升高,分别为(192.5±45.6)μg/L、(0.083±0.011)μg/L;治疗后24 h时,趋于正常,分别为(184.7±44.2)μg/L、(0.066±0.007)μg/L;治疗后3 d时,恢复至接近正常水平,分别为(100.3±25.8)μg/L、(0.031±0.008)μg/L。结论对急性心肌梗塞患者行血清肌红蛋白检验,不仅具有良好的诊断作用,同时其还能准确判断患者病情严重程度,从而为临床治疗提供可靠的依据。
Objective To explore and analyze the application value of serum myoglobin test in clinical examination of acute myocardial infarction. Methods A total of 122 patients with acute myocardial infarction admitted to our hospital from January 2014 to December 2015 were convenient selected as study subjects(study group), and 122 subjects who underwent health checkups in our hospital were selected as reference subjects(set as control group), the two groups of subjects were tested for serum myoglobin, and the serum myoglobin and serum troponin-1 levels were compared between the two groups,and the patients in the study group were treated at 4 h, 24 h, and 3 d after treatment. The serum myoglobin was retested,and the changes of serum myoglobin and serum troponin-1 levels were observed and compared. Results Serum myoglobin and serum troponin I levels(189.6±44.5)μg/L and(0.067±0.008)μg/L were significantly higher in the study group than in the control group(56.9 ±14.3) μg/L,(0.001 1 ±0.002)μg/L, the two groups were statistically significant(t =8.925, P <0.05 t=11.257, P<0.05); the study group patients at 4 h after treatment, serum myoglobin, serum muscle calcium level of protein l was significantly increased(192.5±45.6)μg/L,(0.083±0.011)μg/L; at 24 h after treatment, it was normal,(184.7±44.2) μg/L,(0.066± 0.007)μg/L; at 3 days after treatment, it returned to near normal levels, which were(100.3±25.8) μg/L and(0.031±0.008)μg/L, respectively. Conclusion The serum myoglobin test in patients with acute myocardial infarction not only has a good diagnostic effect, but also can accurately determine the severity of the patient's condition, thus providing a reliable basis for clinical treatment.
Objective To explore and analyze the application value of serum myoglobin test in clinical examination of acute myocardial infarction. Methods A total of 122 patients with acute myocardial infarction admitted to our hospital from January 2014 to December 2015 were convenient selected as study subjects(study group), and 122 subjects who underwent health checkups in our hospital were selected as reference subjects(set as control group), the two groups of subjects were tested for serum myoglobin, and the serum myoglobin and serum troponin-1 levels were compared between the two groups,and the patients in the study group were treated at 4 h, 24 h, and 3 d after treatment. The serum myoglobin was retested,and the changes of serum myoglobin and serum troponin-1 levels were observed and compared. Results Serum myoglobin and serum troponin I levels(189.6±44.5)μg/L and(0.067±0.008)μg/L were significantly higher in the study group than in the control group(56.9 ±14.3) μg/L,(0.001 1 ±0.002)μg/L, the two groups were statistically significant(t =8.925, P <0.05 t=11.257, P<0.05); the study group patients at 4 h after treatment, serum myoglobin, serum muscle calcium level of protein l was significantly increased(192.5±45.6)μg/L,(0.083±0.011)μg/L; at 24 h after treatment, it was normal,(184.7±44.2) μg/L,(0.066± 0.007)μg/L; at 3 days after treatment, it returned to near normal levels, which were(100.3±25.8) μg/L and(0.031±0.008)μg/L, respectively. Conclusion The serum myoglobin test in patients with acute myocardial infarction not only has a good diagnostic effect, but also can accurately determine the severity of the patient's condition, thus providing a reliable basis for clinical treatment.
引文
[1]吕海光,王环宇,李真,等.血清肌红蛋白检测在急性心肌梗死临床检验中的应用效果分析[J].中国实用医药,2018,13(31):44-45.
[2]郑玉芳.血清肌红蛋白检验在AMI患者中的临床价值[J].医学理论与实践,2016,29(15):2087-2088.
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[4]章辉.血清肌红蛋白检验在急性心肌梗死患者中的临床价值分析[J].世界最新医学信息文摘,2017,17(22):91.
[5]张丽红.血清肌钙与肌红蛋白联合检验对急性心肌梗死患者的诊断价值分析[J].中西医结合心血管病电子杂志,2016,4(33):58-59.
[6]田大斌,蒋祖辉.血清肌红蛋白、cTnI检测在急性心肌梗死的临床诊断价值及炎症因子水平[J].国际检验医学杂志,2017,38(7):953-955.
[7]尤鑫.血清肌钙与肌红蛋白联合检验对急性心肌梗死患者的诊断价值分析[J].中西医结合心血管病电子杂志,2016,4(21):71-72.
[8]赵荣超,李洁平,赵亚军.心肌标志物检测对急性心肌梗死的诊断价值[J].中国现代药物应用,2016,10(12):22-23.
[9]苗庄,刘刚.血清肌红蛋白检验对急性心肌梗死患者的临床意义探讨[J].中国继续医学教育,2016,8(15):45-46.
[10]张丽红.血清肌钙与肌红蛋白联合检验对急性心肌梗死患者的诊断价值分析[J].中西医结合心血管病电子杂志,2016,4(21):58-59.
[11]陈慧,许慧.血清肌红蛋白检验在急性心肌梗塞临床检验中的应用价值探讨[J].世界最新医学信息文摘,2018,18(88):221,223.
[2]郑玉芳.血清肌红蛋白检验在AMI患者中的临床价值[J].医学理论与实践,2016,29(15):2087-2088.
[3]赵秀清.血清肌红蛋白检验在急性心肌梗塞临床检验中的应用效果分析[J].中国医疗设备,2017,32(S1):137-138.
[4]章辉.血清肌红蛋白检验在急性心肌梗死患者中的临床价值分析[J].世界最新医学信息文摘,2017,17(22):91.
[5]张丽红.血清肌钙与肌红蛋白联合检验对急性心肌梗死患者的诊断价值分析[J].中西医结合心血管病电子杂志,2016,4(33):58-59.
[6]田大斌,蒋祖辉.血清肌红蛋白、cTnI检测在急性心肌梗死的临床诊断价值及炎症因子水平[J].国际检验医学杂志,2017,38(7):953-955.
[7]尤鑫.血清肌钙与肌红蛋白联合检验对急性心肌梗死患者的诊断价值分析[J].中西医结合心血管病电子杂志,2016,4(21):71-72.
[8]赵荣超,李洁平,赵亚军.心肌标志物检测对急性心肌梗死的诊断价值[J].中国现代药物应用,2016,10(12):22-23.
[9]苗庄,刘刚.血清肌红蛋白检验对急性心肌梗死患者的临床意义探讨[J].中国继续医学教育,2016,8(15):45-46.
[10]张丽红.血清肌钙与肌红蛋白联合检验对急性心肌梗死患者的诊断价值分析[J].中西医结合心血管病电子杂志,2016,4(21):58-59.
[11]陈慧,许慧.血清肌红蛋白检验在急性心肌梗塞临床检验中的应用价值探讨[J].世界最新医学信息文摘,2018,18(88):221,223.