核磁共振联合超声在胎儿中枢神经系统畸形诊断中的应用研究
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摘要
目的:探讨核磁共振联合超声在胎儿中枢神经系统畸形诊断中的应用价值。方法:回顾分析重庆市万州区妇幼保健院2016年7月—2018年6月收治的胎儿中枢神经系统畸形患儿合计30例,所有胎儿均接受核磁共振联合超声诊断,比较2中诊断方式的临床疗效。结果:超声检查与核磁共振检查时特异性无明显变化(P> 0.05);联合检测准确性与敏感性均显著优于单纯的超声检测与核磁共振检测,差异有统计学价值(P <0.05)。结论:在临床医学中,核磁共振联合超声在胎儿中枢神经系统畸形诊断中的应用价值价值极佳,有良好的临床诊断价值。
Objective To explore the value of nuclear magnetic resonance combined with ultrasound in the diagnosis of fetal central nervous system malformation.Methods A total of 30 children with fetal central nervous system malformation treated in the maternal and child health care hospital of Wanzhou District of Chongqing city from July 2016 to June 2018 were reviewed and analyzed.All fetuses were diagnosed with MRI combined with ultrasound,and the clinical efficacy of the two diagnostic methods was compared.Results There was no significant change in specificity between ultrasonography and MRI(P>0.05).The accuracy and sensitivity of combined detection were significantly better than those of pure ultrasound and nuclear magnetic resonance imaging.The difference was statistically significant(P<0.05).Conclusion In clinical medicine,the value of nuclear magnetic resonance combined with ultrasound in the diagnosis of fetal central nervous system malformation is of great value and has good clinical diagnostic value.
Objective To explore the value of nuclear magnetic resonance combined with ultrasound in the diagnosis of fetal central nervous system malformation.Methods A total of 30 children with fetal central nervous system malformation treated in the maternal and child health care hospital of Wanzhou District of Chongqing city from July 2016 to June 2018 were reviewed and analyzed.All fetuses were diagnosed with MRI combined with ultrasound,and the clinical efficacy of the two diagnostic methods was compared.Results There was no significant change in specificity between ultrasonography and MRI(P>0.05).The accuracy and sensitivity of combined detection were significantly better than those of pure ultrasound and nuclear magnetic resonance imaging.The difference was statistically significant(P<0.05).Conclusion In clinical medicine,the value of nuclear magnetic resonance combined with ultrasound in the diagnosis of fetal central nervous system malformation is of great value and has good clinical diagnostic value.
引文
[1]张锋,丁中,陈京喆,等.二维超声联合四维超声在胎儿畸形诊断中的应用[N].蚌埠医学院学报,2016,41(1):96-98.
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[13]林莲恩,黎新艳,姚慧,等.胎儿骨骼系统畸形的产前超声诊断分析[J].中国妇幼保健,2016,31(3):620-622.
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[2]胡剑,王相玉,何媛,等.超声及MRI诊断胎儿中枢神经系统畸形灵敏度、特异度比较[J].现代仪器与医疗,2016,22(4):4-5.
[3]张晓斌,张海燕,胡振芳,等.磁共振成像在中晚孕胎儿中枢神经系统畸形中的诊断价值分析[J].四川医学,2017,38(10):1201-1204.
[4]师晓娟,张鑫,张昕,等.超声结构筛查在胎儿中枢神经系统畸形的鉴别诊断中的应用研究[J].河北医学,2017(12):2021-2024.
[5]陶斯翠,李建蓉,梁辉,等.超声与MRI在疑似高危胎儿中枢神经系统异常筛查中应用研究[J].中国CT和MRI杂志,2017,15(4):14-16.
[6]王茜,曹爱红,张涛,等.产前超声联合磁共振对胎儿发育畸形的对比研究[J].世界最新医学信息文摘,2017(25):12-14.
[7]彭勇进,王静茹,黄崇闲,等.超声联合MRI对胎儿中枢神经系统发育异常的诊断价值[J].深圳中西医结合杂志,2016(23):54-55.
[8]段亚萍.早期超声诊断在11~14孕周胎儿神经系统畸形中的价值研究[J].临床医学研究与实践,2016,1(19):141-143.
[9]霍晓恺,刘泰石,解耀锃.早孕期超声筛查在胎儿结构畸形诊断中的应用[J].中国妇幼健康研究,2016,27(9):1071-1073.
[10]李彦,黄文起,林光耀.二维联合三维超声在产前早孕晚期胎儿心脏畸形诊断中的应用研究[J].医学影像学杂志,2017,27(9):1676-1678.
[11]张旭辉,陈晓荣,张珊珊,等.超声与MRI对胎儿神经系统发育异常的诊断分析[J].磁共振成像,2016,7(7):487-490.
[12]陈艺菲.磁共振成像诊断产前先天性畸形的临床效果[J].中国妇幼保健,2017,32(8):1791-1793.
[13]林莲恩,黎新艳,姚慧,等.胎儿骨骼系统畸形的产前超声诊断分析[J].中国妇幼保健,2016,31(3):620-622.
[14]BALDOLIC,RIGHINIA,PARAZZINIC,et al.Demon stration of acute is chemic lesions in the fetal bra in by diffusion magnetic resonance imang[J].Ann Neur,2012,52(2):243-246.
[15]FULFOR D J,VADEYARSH,DODAMPAHALASH,et a1.Fetal brain act vity in response to a visual stimulus[J].Hum Bra in Mapp,2013,20(4):239-245.
[16]冯蓓.四维超声检查在胎儿泌尿生殖系统畸形诊断中的应用价值[J].中华全科医学,2017(6):1019-1021.